PD 158780
- Product Name
- PD 158780
- Chemical Name
- PD 158780
- Synonyms
- PD 158780;4-[(3-BROMOPHENYL)AMINO]-6-(METHYLAMINO)-PYRIDO[3,4-D]PYRIDIMINE
- CBNumber
- CB5326060
- Molecular Formula
- C14H12BrN5
- Formula Weight
- 330.18
- MOL File
- Mol file
More
Less
PD 158780 Property
- storage temp.
- -20°C
More
Less
N-Bromosuccinimide Price
Tocris
- Product number
- 2615
- Product name
- PD 158780
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $212
- Updated
- 2021/12/16
Tocris
- Product number
- 2615
- Product name
- PD 158780
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $891
- Updated
- 2021/12/16
Usbiological
- Product number
- 256184
- Product name
- PD 158780
- Packaging
- 10mg
- Price
- $466
- Updated
- 2021/12/16
More
Less
PD 158780 Chemical Properties,Usage,Production
Uses
PD 158780 is a potent tyrosine kinase inhibitor of the epidermal growth factor receptor and has been shown to delay substantial growth of tumors in vivo tumor models.
Enzyme inhibitor
This photosensitive pyridopyrimidine (FW = 330.19 g/mol), known systematically as 4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4- d]pyridimine, inhibits EPGFR (epidermal growth factor receptor) proteintyrosine kinase (IC50 = 8 pM). In addition, PD 158780 inhibits heregulinstimulated autophosphorylation in SK-BR-3 (IC50 = 49 nM) and MDA-MB- 453 (IC50 = 52 nM) breast carcinomas.
PD 158780 Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
PD 158780 Suppliers
- Tel
- --
- Fax
- --
- info-tech@nacalai.co.jp
- Country
- Japan
- ProdList
- 6046
- Advantage
- 75
- Tel
- --
- Fax
- --
- reag-info@gms.kanto.co.jp
- Country
- Japan
- ProdList
- 6756
- Advantage
- 74
PD 158780Related Search:
PD168393
4-(4-FLUOROPHENYL)-2-(4-NITROPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE
PD153035 HCl
N-[2-[[4-(DIETHYLAMINO)BUTYL]AMINO-6-(3,5-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDIN-7-YL]-N'-(1,1-DIMETHYLETHYL)UREA
PD 166866