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HC≡C-CH2-PEG6-SH

Product Name
HC≡C-CH2-PEG6-SH
CAS No.
1422540-91-7
Chemical Name
HC≡C-CH2-PEG6-SH
Synonyms
HC≡C-CH2-PEG6-SH;Propargyl-PEG6-SH;3,6,9,12,15,18-hexaoxahenicos-20-yne-1-thiol;3,6,9,12,15,18-Hexaoxaheneicos-20-yne-1-thiol
CBNumber
CB53309419
Molecular Formula
C15H28O6S
Formula Weight
336.44
MOL File
1422540-91-7.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

purepeg
Product number
437906
Product name
HC≡C-CH2-PEG6-SH
Purity
min.95%
Packaging
1g
Price
$444
Updated
2021/12/16
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HC≡C-CH2-PEG6-SH Chemical Properties,Usage,Production

Biological Activity

Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

HC≡C-CH2-PEG6-SH Preparation Products And Raw materials

Raw materials

Preparation Products

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1422540-91-7, HC≡C-CH2-PEG6-SHRelated Search:


  • HC≡C-CH2-PEG6-SH
  • Propargyl-PEG6-SH
  • 3,6,9,12,15,18-Hexaoxaheneicos-20-yne-1-thiol
  • 3,6,9,12,15,18-hexaoxahenicos-20-yne-1-thiol
  • 1422540-91-7
  • C15H28O6S
  • peg