ChemicalBook > CAS DataBase List > 3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE

3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE

Product Name: 3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE
CAS No.: 16789-84-7
Chemical Name: 3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE
Synonyms: AKOS BC-1820;ASISCHEM R25237;3-BROMO-5-NITROSALICYLALDEHYDE;3-Bromo-5-nitrosalicylaldehyde >3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE;2-Hydroxy-3-bromo-5-nitrobenzaldehyde;Benzaldehyde, 3-bromo-2-hydroxy-5-nitro-;3-BROMO-2-HYDROXY-5-NITROBENZENECARBALDEHYDE
CBNumber: CB5333037
Molecular Formula: C7H4BrNO4
Formula Weight: 246.01
MOL File: 16789-84-7.mol

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3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE Property

Melting point:: 146-149 °C
Boiling point:: 299.6±40.0 °C(Predicted)
Density: 1.928±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder to crystal
pka: 3.38±0.44(Predicted)
color: Light orange to Yellow to Green
Sensitive: Air Sensitive
BRN: 1213613
InChI: InChI=1S/C7H4BrNO4/c8-6-2-5(9(12)13)1-4(3-10)7(6)11/h1-3,11H
InChIKey: BESBCGANGAEHPM-UHFFFAOYSA-N
SMILES: C(=O)C1=CC([N+]([O-])=O)=CC(Br)=C1O
CAS DataBase Reference: 16789-84-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22
Safety Statements: 36/37
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
HazardClass: IRRITANT
PackingGroup: III
HS Code: 2913000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 652784
Product name: 3-Bromo-5-nitrosalicylaldehyde
Purity: 97%
Packaging: 1g
Price: $102
Updated: 2023/06/20

Sigma-Aldrich

Product number: 652784
Product name: 3-Bromo-5-nitrosalicylaldehyde
Purity: 97%
Packaging: 5g
Price: $303
Updated: 2023/06/20

TCI Chemical

Product number: B3198
Product name: 3-Bromo-5-nitrosalicylaldehyde
Purity: >95.0%(GC)(T)
Packaging: 1g
Price: $52
Updated: 2025/07/31

TCI Chemical

Product number: B3198
Product name: 3-Bromo-5-nitrosalicylaldehyde
Purity: >95.0%(GC)(T)
Packaging: 5g
Price: $192
Updated: 2025/07/31

TRC

Product number: B677933
Product name: 3-Bromo-2-hydroxy-5-nitrobenzaldehyde
Packaging: 25mg
Price: $45
Updated: 2021/12/16

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3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE Chemical Properties,Usage,Production

Synthesis Reference(s)

The Journal of Organic Chemistry, 72, p. 5867, 2007 DOI: 10.1021/jo070477u

Synthesis

97-51-8

16789-84-7

General procedure for the synthesis of 3-bromo-2-hydroxy-5-nitrobenzaldehyde from 5-nitrosalicylaldehyde: 2-hydroxy-5-nitrobenzaldehyde (2.0 g, 12 mmol) and dichloromethane (30 mL) were added to a 100 mL two-necked flask, followed by the addition of bromine (2.24 g, 14 mmol) dropwise. The reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the reaction was quenched with saturated aqueous sodium thiosulfate (100 mL) and the mixture was transferred to a separatory funnel for layering. The aqueous phase was extracted with ethyl acetate (100 mL × 2). The organic phases were combined, washed with saturated brine (80 mL × 2), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: ethyl acetate/petroleum ether, v/v = 1/20) to afford 3-bromo-2-hydroxy-5-nitrobenzaldehyde as a yellow solid (2.89 g, 98% yield). Mass spectrum (ES-API, cation mode) m/z: 246.9 [M + 2]+.

References

[1] Organic Letters, 2011, vol. 13, # 1, p. 26 - 29
[2] Tetrahedron Letters, 2005, vol. 46, # 51, p. 8959 - 8963
[3] Patent: WO2017/36404, 2017, A1. Location in patent: Page/Page column 115
[4] Journal of Organic Chemistry, 2007, vol. 72, # 15, p. 5867 - 5869
[5] Patent: CN108623615, 2018, A. Location in patent: Paragraph 0332; 0547; 0548; 0549

3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE Suppliers

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View Lastest Price from 3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE manufacturers

Career Henan Chemical Co

Product: 3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE 16789-84-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,100kg
Release date: 2019-07-04

16789-84-7, 3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDERelated Search:

3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE 5-Nitrosalicylaldehyde RARECHEM AL BE 0950 3-BROMO-2-HYDROXY-4-METHYL-5-NITRO-BENZALDEHYDE 3-BROMO-4-HYDROXY-5-NITROBENZALDEHYDE 5-BROMO-2-HYDROXY-3-NITROBENZALDEHYDE 5-bromo-2-hydroxy-3-nitrobenzaldehyde [4-(4-bromoanilino)-6-(3,5-dimethyl-1H-pyrazol-1-yl)-1,3,5-triazin-2-yl]hydrazone 3-bromo-2-hydroxy-5-nitrobenzaldehyde (4,6-diphenyl-2-pyrimidinyl)hydrazone 3-bromo-2-hydroxy-5-nitrobenzaldehyde (2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazone 3-BROMO-2,6-DIMETHOXY-5-NITROBENZOIC ACID RARECHEM AL BF 0950 3-BROMO-2-HYDROXY-4,6-DIMETHYL-5-NITRO-BENZALDEHYDE 3-BROMO-2,6-DIMETHOXY-5-NITROBENZAMIDE N-(3-BROMO-2,6-DIMETHOXY-5-NITROBENZOYL)-N'-(2,3,4,5,6-PENTAFLUOROPHENYL)UREA RARECHEM AL BO 2199 3-bromo-2-hydroxy-5-nitrobenzaldehyde (4-(dibutylamino)-6-{4-nitroanilino}-1,3,5-triazin-2-yl)hydrazone 5-bromo-2-hydroxy-3-nitrobenzaldehyde [4-(benzylamino)-6-(dimethylamino)-1,3,5-triazin-2-yl]hydrazone 5-bromo-2-hydroxy-3-nitrobenzaldehyde [4-anilino-6-(3,5-dimethyl-1H-pyrazol-1-yl)-1,3,5-triazin-2-yl]hydrazone

ASISCHEM R25237

3-BROMO-5-NITROSALICYLALDEHYDE

2-Hydroxy-3-bromo-5-nitrobenzaldehyde

3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE

3-BROMO-2-HYDROXY-5-NITROBENZENECARBALDEHYDE

AKOS BC-1820

3-Bromo-5-nitrosalicylaldehyde &gt

Benzaldehyde, 3-bromo-2-hydroxy-5-nitro-

16789-84-7

Aromatic Aldehydes & Derivatives (substituted)

C7Organic Building Blocks

Aldehydes

Carbonyl Compounds

Nitro Compounds

Nitrogen Compounds