ChemicalBook > CAS DataBase List > Ac-Gly-BoroPro

Ac-Gly-BoroPro

Product Name
Ac-Gly-BoroPro
CAS No.
886992-99-0
Chemical Name
Ac-Gly-BoroPro
Synonyms
Ac-Gly-BoroPro;Ac-Gly-BoroPro?, >98%;AcGlyBoroPro,Ac Gly BoroPro;Boronic acid, B-[(2S)-1-[2-(acetylamino)acetyl]-2-pyrrolidinyl]-
CBNumber
CB53339599
Molecular Formula
C8H15BN2O4
Formula Weight
214.03
MOL File
886992-99-0.mol
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Ac-Gly-BoroPro Property

Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C,unstable in solution, ready to use.
solubility 
DMSO : ≥ 50 mg/mL (233.61 mM)
form 
Solid
pka
9.72±0.20(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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Ac-Gly-BoroPro Chemical Properties,Usage,Production

Biological Activity

Ac-Gly-BoroPro is a selective FAP inhibitor with a Ki value of 23 nM.

in vitro

FAP has been implicated in cancer; however, its specific role remains elusive because inhibitors that distinguish FAP from other prolyl peptidases like dipeptidyl peptidase-4 (DPP-4) have not been developed. Ac-Gly-BoroPro selectively inhibits FAP relative to other prolyl peptidases. FAP reacts readily with submicromolar concentrations of Ac-Gly-BoroPro, reaching steady state inhibition levels rapidly (K i =23±3 nM).

target

Ki: 23 nM (FAP)

Ac-Gly-BoroPro Preparation Products And Raw materials

Raw materials

Preparation Products

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Ac-Gly-BoroPro Suppliers

CHINA 17 United States 4 USA 1 Global 22
Beijing xinyanhui pharmaceutical research and development co., LTD
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13969155946
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1461866103@qq.com
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China
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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sales@chemegen.com
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Shanghai Zeye Biotechnology Co., Ltd.
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021-61998551 13122364865
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Nanchang Tianzhen Biotechnology Co., Ltd
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13173652190
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pomy@tanzhenbio.com
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Ontores Biotech
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0571-88760729 18072970094
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supports@ontorespeptide.com
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Nanjing Shizhou Biology Technology Co.,Ltd
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025-85560043 13675144456
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025-85563444
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 15801484223;
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psaitong@jm-bio.com
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TargetMol Chemicals Inc.
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Shanghai Maclean Biochemical Technology Co., LTD
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021-50706066 15221275939
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shenlinxing@macklin.cn
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Jilin Chinese Academy of Sciences-yanshen Technology
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+undefined18143011203
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info@chemextension.com
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Wuxi Laifusi Biological Experimental Equipment Co., Ltd.
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Guangzhou Weijia Technology Co., Ltd.
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Jiangxi Jianglan Pure Biological Reagent Co., Ltd.
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Shanghai Qiming Biological Technology Co., Ltd.
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Shanghai Wowu Biological Technology Co., Ltd.
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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886992-99-0, Ac-Gly-BoroProRelated Search:


  • Ac-Gly-BoroPro
  • Ac-Gly-BoroPro?, >98%
  • Boronic acid, B-[(2S)-1-[2-(acetylamino)acetyl]-2-pyrrolidinyl]-
  • AcGlyBoroPro,Ac Gly BoroPro
  • 886992-99-0