ChemicalBook > CAS DataBase List > BocNH-PEG7-OH

BocNH-PEG7-OH

Product Name
BocNH-PEG7-OH
CAS No.
1292268-13-3
Chemical Name
BocNH-PEG7-OH
Synonyms
tert-Butyl (20-hydroxy-3,6,9,12,15,18-hexaoxaicosyl)carbamate;NHBoc-PEG7-OH;BocNH-PEG7-OH;BocNH-PEG7-alcohol;N-Boc-PEG7-alcohol N-Boc-;t-boc-N-amido-PEG7-alcohol;20-(Boc-amino)-3,6,9,12,15,18-hexaoxa-1-icosanol;t-butyl20-hydroxy-3,6,9,12,15,18-hexaoxaicosylcarbamate;5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester;BocNH-PEG7-OH/5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester
CBNumber
CB53340579
Molecular Formula
C19H39NO9
Formula Weight
425.51
MOL File
1292268-13-3.mol
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BocNH-PEG7-OH Property

Boiling point:
521.1±50.0 °C(Predicted)
Density 
1.090±0.06 g/cm3(Predicted)
solubility 
Soluble in Water, DMSO, DCM, DMF
pka
12.23±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23546
Product name
N-Boc-PEG7-alcohol
Purity
98%
Packaging
500mg
Price
$280
Updated
2021/12/16
Activate Scientific
Product number
AS104083
Product name
BocNH-PEG7-OH
Purity
95+%
Packaging
1g
Price
$615
Updated
2021/12/16
purepeg
Product number
432407
Product name
BocNH-PEG7-OH
Purity
min.95%
Packaging
1g
Price
$350
Updated
2021/12/16
purepeg
Product number
432407
Product name
BocNH-PEG7-OH
Purity
min.95%
Packaging
250mg
Price
$185
Updated
2021/12/16
Acrotein
Product number
B-0973
Product name
BocNH-PEG7-OH
Purity
97%
Packaging
0.25g
Price
$192.5
Updated
2021/12/16
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BocNH-PEG7-OH Chemical Properties,Usage,Production

Description

N-Boc-PEG7-alcohol is a PEG linker containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Biological Activity

N-Boc-PEG7-alcohol is a PROTAC bridge that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. Also it is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).

in vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

PEGs

Alkyl/ether

BocNH-PEG7-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BocNH-PEG7-OH Suppliers

Guangzhou Hongyuan Chemical Co.,Ltd
Tel
15817493340
Email
981810490@qq.com
Country
China
ProdList
405
Advantage
58
PharmaBlock Sciences (Nanjing),Inc.
Tel
400-0255188 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9900
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9452
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5877
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12357
Advantage
58
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1246
Advantage
55
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12308
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28821
Advantage
58
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View Lastest Price from BocNH-PEG7-OH manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
NHBoc-PEG7-OH 1292268-13-3
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-25

1292268-13-3, BocNH-PEG7-OHRelated Search:


  • BocNH-PEG7-OH
  • NHBoc-PEG7-OH
  • 5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester
  • t-boc-N-amido-PEG7-alcohol
  • t-butyl20-hydroxy-3,6,9,12,15,18-hexaoxaicosylcarbamate
  • tert-Butyl (20-hydroxy-3,6,9,12,15,18-hexaoxaicosyl)carbamate
  • 20-(Boc-amino)-3,6,9,12,15,18-hexaoxa-1-icosanol
  • BocNH-PEG7-OH/5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester
  • BocNH-PEG7-alcohol
  • N-Boc-PEG7-alcohol N-Boc-
  • tert-butyl N-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
  • 1292268-13-3
  • C19H39NO9
  • peg