BocNH-PEG7-OH
- Product Name
- BocNH-PEG7-OH
- CAS No.
- 1292268-13-3
- Chemical Name
- BocNH-PEG7-OH
- Synonyms
- tert-Butyl (20-hydroxy-3,6,9,12,15,18-hexaoxaicosyl)carbamate;NHBoc-PEG7-OH;BocNH-PEG7-OH;BocNH-PEG7-alcohol;t-Boc-Amido-PEG7-Alcohol;N-Boc-PEG7-alcohol N-Boc-;t-boc-N-amido-PEG7-alcohol;20-(Boc-amino)-3,6,9,12,15,18-hexaoxa-1-icosanol;t-butyl20-hydroxy-3,6,9,12,15,18-hexaoxaicosylcarbamate;5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester
- CBNumber
- CB53340579
- Molecular Formula
- C19H39NO9
- Formula Weight
- 425.51
- MOL File
- 1292268-13-3.mol
BocNH-PEG7-OH Property
- Boiling point:
- 521.1±50.0 °C(Predicted)
- Density
- 1.090±0.06 g/cm3(Predicted)
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 12.23±0.46(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- BP-23546
- Product name
- N-Boc-PEG7-alcohol
- Purity
- 98%
- Packaging
- 500mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- AS104083
- Product name
- BocNH-PEG7-OH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $615
- Updated
- 2021/12/16
- Product number
- 432407
- Product name
- BocNH-PEG7-OH
- Purity
- min.95%
- Packaging
- 1g
- Price
- $350
- Updated
- 2021/12/16
- Product number
- 432407
- Product name
- BocNH-PEG7-OH
- Purity
- min.95%
- Packaging
- 250mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- B-0973
- Product name
- BocNH-PEG7-OH
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $192.5
- Updated
- 2021/12/16
BocNH-PEG7-OH Chemical Properties,Usage,Production
Description
N-Boc-PEG7-alcohol is a PEG linker containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Biological Activity
N-Boc-PEG7-alcohol is a PROTAC bridge that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. Also it is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).
in vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
Cleavable
| PEGs
| Alkyl/ether
|
BocNH-PEG7-OH Preparation Products And Raw materials
Raw materials
Preparation Products
BocNH-PEG7-OH Suppliers
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View Lastest Price from BocNH-PEG7-OH manufacturers
- Product
- NHBoc-PEG7-OH 1292268-13-3
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-25