Phe-Met-Arg-Phe amide trifluoroacetate

Product Name: Phe-Met-Arg-Phe amide trifluoroacetate
CAS No.: 159237-99-7
Chemical Name: Phe-Met-Arg-Phe amide trifluoroacetate
Synonyms: Phe-Met-Arg-Phe amide trifluoroacetate;PHE-MET-ARG-PHE AMIDE TRIFLUOROACETATE?, >98%;Phe-Met-Arg-Phe amide trifluoroacetate,Phe-Met-Arg-Phe-NH2 trifluoroacetate,FMRF-NH2 trifluoroacetate?, >98%
CBNumber: CB53356170
Molecular Formula: C31H43F3N8O6S
Formula Weight: 712.79
MOL File: 159237-99-7.mol

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Phe-Met-Arg-Phe amide trifluoroacetate Property

storage temp.: Store at -20°C
form: Solid
color: White to off-white
Water Solubility: Water : ≥ 50 mg/mL (60.47 mM)
Sequence: H-Phe-Met-Arg-Phe-NH2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-7708
Product name: Phe-Met-Arg-Pheamidetrifluoroacetate
Purity: ≥98.0%
Packaging: 5mg
Price: $96
Updated: 2021/12/16

ChemScene

Product number: CS-7708
Product name: Phe-Met-Arg-Pheamidetrifluoroacetate
Purity: ≥98.0%
Packaging: 10mg
Price: $144
Updated: 2021/12/16

ChemScene

Product number: CS-7708
Product name: Phe-Met-Arg-Pheamidetrifluoroacetate
Purity: ≥98.0%
Packaging: 25mg
Price: $228
Updated: 2021/12/16

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Phe-Met-Arg-Phe amide trifluoroacetate Chemical Properties,Usage,Production

Uses

Phe-Met-Arg-Phe amide trifluoroacetate is an activator of K+ current, with ED50 of 23 nM in the peptidergic caudodorsal neurons.

in vivo

Phe-Met-Arg-Phe amide (FMRFamide) stimulates growth hormone secretion in conscious OVX rats. The presence of Phe-Met-Arg-Phe amide-like immunoreactivity in neuronal elements in the hypothalamus suggested a role for this in the hypothalamic control of the anterior pituitary function. The injection of 200 ng (313.8 picomoles) of FMRFamide (in 2 uL) produces a significantly increased plasma GH 15 min after injection. The GH-increasing effect of 400-800 ng (627-1255 picomoles) of FMRFamide is already developed after 5 min and lasted up to 30 min^[3].

References

[1] Kits KS, et al. Phe-Met-Arg-Phe-amide activates a novel voltage-dependent K+ current through a lipoxygenasepathway in molluscan neurones. J Gen Physiol. 1997 Nov;110(5):611-28. DOI:10.1085/jgp.110.5.611
[2] Sorenson RL, et al. Phe-met-arg-phe-amide (FMRF-NH2) inhibits insulin and somatostatin secretion and anti-FMRF-NH2 sera detects pancreatic polypeptide cells in the rat islet. Peptides. 1984 Jul-Aug;5(4):777-82. DOI:10.1016/0196-9781(84)90021-4
[3] Ottlecz A, et al. Phe-Met-Arg-Phe-amide (FMRFamide) stimulated growth hormone secretion in conscious OVX rats. Neuropeptides. 1987 Feb-Mar;9(2):161-7. DOI:10.1016/0143-4179(87)90054-0

Phe-Met-Arg-Phe amide trifluoroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Phe-Met-Arg-Phe amide trifluoroacetate Suppliers

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159237-99-7, Phe-Met-Arg-Phe amide trifluoroacetateRelated Search:

Phe-Met-Arg-Phe amide trifluoroacetate

Phe-Met-Arg-Phe amide trifluoroacetate,Phe-Met-Arg-Phe-NH2 trifluoroacetate,FMRF-NH2 trifluoroacetate?, >98%

PHE-MET-ARG-PHE AMIDE TRIFLUOROACETATE?, >98%

159237-99-7