Aprepitant Impurity 9

Product Name: Aprepitant Impurity 9
CAS No.: 219821-37-1
Chemical Name: Aprepitant Impurity 9
Synonyms: Aprepitant Impurity 9;Aprepitant Impurity 47;Fosaprepitant Impurity U;Aprepitant Open-Ring Methyl Ester Impurity;Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity;Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate;methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate;2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester;Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester
CBNumber: CB53358992
Molecular Formula: C24H25F7N4O4
Formula Weight: 566.47
MOL File: 219821-37-1.mol

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Aprepitant Impurity 9 Property

Density: 1.43±0.1 g/cm3(Predicted)
solubility: soluble in Chloroform, Dichloromethane, Methanol
form: Solid
pka: 7.86±0.43(Predicted)
color: Pale-Yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: D297840
Product name: N-(Destriazolonomethyl)N-(Methylcarboxyacetamidohydrazono)Aprepitant
Packaging: 10mg
Price: $1010
Updated: 2021/12/16

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Aprepitant Impurity 9 Chemical Properties,Usage,Production

Uses

N-(Destriazolonomethyl), N-(Methylcarboxyacetamidohydrazono) Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.

Aprepitant Impurity 9 Preparation Products And Raw materials

Raw materials

Preparation Products

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Aprepitant Impurity 9 Suppliers

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219821-37-1, Aprepitant Impurity 9Related Search:

Aprepitant-M3 Metabolite 4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE Aprepitant Aprepitant Impurity 6 Fosaprepitant Impurity 6 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one Aprepitant (S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one Aprepitant Impurity 17 (2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Fosaprepitant Benzyl Ester [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine (2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Defluoro Aprepitant Aprepitant Impurity A Enantiomer 5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one Aprepitant Impurity 11 HCl Aprepitant Impurity 2

Aprepitant Impurity 9

Aprepitant Open-Ring Methyl Ester Impurity

2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester

Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity

Aprepitant Impurity 47

Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate

Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester

methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate

Fosaprepitant Impurity U

219821-37-1

C24H25F7N4O4