NH-(PEG3-azide)2
- Product Name
- NH-(PEG3-azide)2
- CAS No.
- 1258939-39-7
- Chemical Name
- NH-(PEG3-azide)2
- Synonyms
- NH-(PEG3-azide)2;NH-bis(PEG3-azide);HN-(PEG3-CH2CH2N3)2;HN-(PEG3-CH2CH2N3)2/Ethanamine,2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-
- CBNumber
- CB53363970
- Molecular Formula
- C16H33N7O6
- Formula Weight
- 419.47652
- MOL File
- 1258939-39-7.mol
NH-(PEG3-azide)2 Property
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-23312
- Product name
- NH-bis(PEG3-azide)
- Purity
- 98%
- Packaging
- 500mg
- Price
- $1470
- Updated
- 2021/12/16
NH-(PEG3-azide)2 Chemical Properties,Usage,Production
Description
NH-bis(PEG3-azide) is a click chemistry PEG reagent containing an amino group with two azide groups. The amino group can react with carboxylic acids, activated NHS esters. The azide groups enable Click Chemistry with alkyne such as DBCO, BCN or propargyl reagents.
Uses
NH-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH-bis(PEG3-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
NH-(PEG3-azide)2 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from NH-(PEG3-azide)2 manufacturers
- Product
- NH-bis(PEG3-azide) 1258939-39-7
- Price
- US $2.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-08-06
- Product
- NH-bis(PEG3-azide) 1258939-39-7
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >95.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-28