Ripretinib

Product Name: Ripretinib
CAS No.: 1442472-39-0
Chemical Name: Ripretinib
Synonyms: KIT/PDGFR INHIBITOR(DCC-2618);Ripretinib (DCC-2618);Ripretinib;DCC-2618 HCl;13C6]-Ripretinib;KIT/PDGFR inhibitor;Ripretinib USP/EP/BP;Ripretinib Impurity 3;Oliceridine Impurity 17;KIT/PDGFR inhibitor(DCC2618)
CBNumber: CB53365156
Molecular Formula: C24H21BrFN5O2
Formula Weight: 510.36
MOL File: 1442472-39-0.mol

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Ripretinib Property

Boiling point:: 568.6±50.0 °C(Predicted)
Density: 1.544±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:25.0(Max Conc. mg/mL);49.0(Max Conc. mM)
form: A solid
pka: 12.15±0.70(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0044835
Product name: Ripretinib
Purity: 98.90%
Packaging: 5mg
Price: $210
Updated: 2021/12/16

ChemScene

Product number: CS-0044835
Product name: Ripretinib
Purity: 98.90%
Packaging: 10mg
Price: $310
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573361
Product name: Ripretinib (DCC-2618)
Purity: >98%
Packaging: 100mg
Price: $986
Updated: 2021/12/16

ChemScene

Product number: CS-0044835
Product name: Ripretinib
Purity: 98.90%
Packaging: 50mg
Price: $1100
Updated: 2021/12/16

ChemScene

Product number: CS-0044835
Product name: Ripretinib
Purity: 98.90%
Packaging: 100mg
Price: $1850
Updated: 2021/12/16

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Ripretinib Chemical Properties,Usage,Production

Uses

Ripretinib is used in the treatment of gastrointestinal stromal tumors (GISTs).

brand name

Qinlock

General Description

Class: receptor tyrosine kinase; Treatment: GIST; Other name: DCC-2618; Elimination half-life = 15 h; Protein binding = 98.8%

Biological Activity

Ripretinib is a highly effective inhibitor of both wild-type KIT and PDGFRA, with IC50 values around 3 nM. It also targets a wide range of KIT and PDGFRA mutants in GIST. Additionally, it inhibits various tumor-driving kinases such as PDGFRβ, TIE2, VEGFR2, and BRAF.

target

Primary targets: PDGFRA, KIT

Ripretinib Preparation Products And Raw materials

Raw materials

Preparation Products

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Ripretinib Suppliers

China 106 India 1 United States 6 Global 113

Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

Tel: +86-027-59232304 15387063101
Email: 2881924050@qq.com
Country: China
ProdList: 9951
Advantage: 58

Chunchuang (Wuhan) Technology Co., Ltd

Tel: 15342225168
Email: yutianchun2007@126.com
Country: China
ProdList: 10002
Advantage: 58

WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.

Tel: 17702719238 17702719238
Email: sales@sun-shinechem.com
Country: China
ProdList: 976
Advantage: 64

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Shanghai XingMo Biotechnology Co., Ltd.

Tel: 13524779951
Fax: QQ: 2075692521
Email: 2075692521@qq.com
Country: China
ProdList: 310
Advantage: 55

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4512
Advantage: 55

Shanghai Biolang biotechnology Co.,Ltd

Tel: 17764003753
Fax: 13669031409
Email: 2326587775@qq.com
Country: China
ProdList: 188
Advantage: 55

Shanghai Biolang biotechnology Co.,Ltd

Tel: 17764003753
Fax: 13669031409
Email: 2326587775@qq.com
Country: China
ProdList: 188
Advantage: 55

Twochem Co.Ltd

Tel: 021-021-58111628 15800915896
Fax: QQ 3285589261
Email: sales@twochem.com
Country: China
ProdList: 304
Advantage: 55

ATK CHEMICAL COMPANY LIMITED

Tel: 3429815786 13301662590
Fax: +86-21-51619052
Email: Mandy@ATKchemical.com
Country: China
ProdList: 8026
Advantage: 55

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View Lastest Price from Ripretinib manufacturers

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Product: Ripretinib 1442472-39-0
Price: US $0.00/g
Min. Order: 1g
Purity: More Than 99%
Supply Ability: 100kg/Month
Release date: 2024-07-19

Dideu Industries Group Limited

Product: Ripretinib 1442472-39-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-17

Career Henan Chemical Co

Product: KIT/PDGFR inhibitor(DCC2618) 1442472-39-0
Price: US $6.68/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-10

1442472-39-0, RipretinibRelated Search:

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KIT/PDGFR inhibitor(DCC2618)

KIT/PDGFR INHIBITOR(DCC-2618)

Ripretinib

Ripretinib (DCC-2618)

DCC-2618; DCC 2618; DCC2618; RIPRETINIB;

DCC-2618;KIT/PDGFR INHIBITOR

KIT/PDGFR inhibitor

N-[4-Bromo-5-[1-ethyl-1,2-dihydro-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-N'-phenylurea

Urea, N-[4-bromo-5-[1-ethyl-1,2-dihydro-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-N'-phenyl-

1-(4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl)-3-phenylurea

Ripretinib USP/EP/BP

DCC-2618 HCl

13C6]-Ripretinib

Ripretinib Impurity 3

Oliceridine Impurity 17

1442472-39-0

C24H21BrFN5O2

API