Parbendazole
- Product Name
- Parbendazole
- CAS No.
- 14255-87-9
- Chemical Name
- Parbendazole
- Synonyms
- pbdz;verminum;skf29044;helmatac;PARBENDAZOLE;Parbendazole (200 mg);Parbendazole (1498706);C15892000 Parbendazole;Parbendazole in Methanol;Parbendazole, 10 mM in DMSO
- CBNumber
- CB5336957
- Molecular Formula
- C13H17N3O2
- Formula Weight
- 247.29
- MOL File
- 14255-87-9.mol
Parbendazole Property
- Melting point:
- 255-257°C
- Boiling point:
- 390.33°C (rough estimate)
- Density
- 1.1214 (rough estimate)
- refractive index
- 1.5700 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 11.66±0.10(Predicted)
- color
- White to Off-White
- Water Solubility
- <0.1 g/100 mL at 18 ºC
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C13H17N3O2/c1-3-4-5-9-6-7-10-11(8-9)15-12(14-10)16-13(17)18-2/h6-8H,3-5H2,1-2H3,(H2,14,15,16,17)
- InChIKey
- YRWLZFXJFBZBEY-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)NC1NC2=CC(CCCC)=CC=C2N=1
- EPA Substance Registry System
- Parbendazole (14255-87-9)
N-Bromosuccinimide Price
- Product number
- 32438
- Product name
- Parbendazole
- Purity
- VETRANAL
- Packaging
- 25mg
- Price
- $120
- Updated
- 2025/07/31
- Product number
- 1498706
- Product name
- Parbendazole
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $432
- Updated
- 2025/07/31
- Product number
- P193260
- Product name
- Parbendazole
- Packaging
- 1g
- Price
- $1320
- Updated
- 2021/12/16
- Product number
- OR305450
- Product name
- Methyl(5-butyl-1H-benzimidazol-2-yl)carbamate
- Purity
- 98%
- Packaging
- 250mg
- Price
- $235
- Updated
- 2021/12/16
- Product number
- G990
- Product name
- Parbendazole
- Packaging
- 100mg
- Price
- $254
- Updated
- 2021/12/16
Parbendazole Chemical Properties,Usage,Production
Chemical Properties
solid
Uses
Antiparasitic
Uses
Parbendazole is a benzimidazole carbamate and a potent inhibitor of microtubule assembly and functions.
Definition
ChEBI: N-(6-butyl-1H-benzimidazol-2-yl)carbamic acid methyl ester is a carbamate ester and a member of benzimidazoles.
General Description
Crystals or fine white powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Parbendazole is a carbamate ester-amine. Amines behave as chemical bases. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition Parbendazole emits toxic fumes.
Fire Hazard
Flash point data for Parbendazole are not available; however, Parbendazole is probably combustible.
Synthesis
Including acetylation, nitration, hydrolysis, reduction, ring-forming five reaction steps, p-n-butyl aniline as raw material, first acetylation with acetic anhydride, and then nitration with nitric acid, the product was poured into the ice-water mixture, precipitated solids, pumping filtration, the filter cake washed with water to neutral, drying to get 4-n-butyl-2-nitro acetanilide; and then the dried product was hydrolyzed with potassium hydroxide solution, then adjusted the pH to 6-7 by using 4mol/L~5mol / L hydrochloric acid to adjust the pH to 6 ~ 7, and then concentrated under reduced pressure, the residue will be extracted with ether, collect the organic phase, concentrate to get 4-n-butyl-2-nitroaniline; will be produced 4-n-butyl-2-nitroaniline methanol as a solvent, add palladium carbon as a catalyst, filtration, filtrate concentration to get 4-n-butyl-o-phenylenediamine, and then methanol as a solvent, acetic acid as an amine salt-forming agent, and methyl cyanocarbamate as a ring-closing agent. Then methanol was used as solvent, acetic acid as amine salting agent and methyl cyanocarbamate as ring-closing agent to produce 5-n-butyl-2-benzimidazolecarbamic acid methyl ester (Parbendazole).
Parbendazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Parbendazole manufacturers
- Product
- Parbendazole 14255-87-9
- Price
- US $55.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1 ton
- Release date
- 2021-12-21
- Product
- Parbendazole 14255-87-9
- Price
- US $13.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 20tons
- Release date
- 2021-12-31
- Product
- Parbendazole 14255-87-9
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-02