HUMAN IGFBP-4
Description Source Background- Product Name
- HUMAN IGFBP-4
- Chemical Name
- HUMAN IGFBP-4
- Synonyms
- IGFBP-4;RAT IGFBP-4;HUMAN IGFBP-4;IGFBP-4 HUMAN;Recombinant Human IGFBP-4/IGFBP4 Protein, His Tag;HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 4;INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-4 HUMAN;HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN IBP-4;HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN HT29-IGF-BP;HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN COLON CANCER CELL GROWTH INHIBITOR
- CBNumber
- CB5338108
- Formula Weight
- 0
- MOL File
- Mol file
HUMAN IGFBP-4 Property
- storage temp.
- −20°C
- form
- lyophilized powder
N-Bromosuccinimide Price
- Product number
- 383377
- Product name
- IGFBP-4
- Packaging
- 96Tests
- Price
- $729
- Updated
- 2021/12/16
- Product number
- 383375
- Product name
- IGFBP-4
- Packaging
- 96Tests
- Price
- $729
- Updated
- 2021/12/16
HUMAN IGFBP-4 Chemical Properties,Usage,Production
Description
IGFBP-4 Human Recombinant amino acids Asp22- Glu258, produced in HEK293 cells and fused with a polyhistidine tag at the C-terminus. IGFBP4 predicted Mw is 27kDa and on SDS-PAGE appears as a 32kDa band under denaturing conditions.
IGFBP4 is purified by proprietary chromatographic techniques.
Source
HEK293 cells
Background
Insulin-like growth factor-binding protein 4 (IGFBP-4) belongs to the insulin-like growth factor binding protein (IGFBP) family. IGFBP4 includes an IGFBP domain and a thyroglobulin type-I domain. IGFBP4 binds both insulin-like growth factors (IGFs) I and II. IGFBP-4 circulates in the plasma in both glycosylated and non-glycosylated forms. IGFBPs can either inhibit or enhance the biological activities of IGF, or act in an IGF independent manner. IGFBP-4 is exceptional since it consistently inhibits several cancer cells in vivo and in vitro, suggesting that it may function as an apoptotic factor. IGFBP4 is produced by all colon cancer cells. Binding of IGFBP-4 prolongs the half-life of the IGFs and changes their interaction with cell surface receptors.
HUMAN IGFBP-4 Preparation Products And Raw materials
Raw materials
Preparation Products
HUMAN IGFBP-4 Suppliers
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