2-(Bromomethyl)-5-(trifluoromethyl)furan

Product Name: 2-(Bromomethyl)-5-(trifluoromethyl)furan
CAS No.: 17515-77-4
Chemical Name: 2-(Bromomethyl)-5-(trifluoromethyl)furan
Synonyms: 2-(BROMOMETHYL)-5-(TRIFLUOROMETHYL)FURAN;2-(Bromomethyl)-5-(trifluoromethyl)furane;Furan,2-(broMoMethyl)-5-(trifluoroMethyl)-;2-(Bromomethyl)-5-(trifluoromethyl)furan97%;2-(Bromomethyl)-5-(trifluoromethyl)furan 97%
CBNumber: CB5355572
Molecular Formula: C6H4BrF3O
Formula Weight: 228.99
MOL File: 17515-77-4.mol

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2-(Bromomethyl)-5-(trifluoromethyl)furan Property

Boiling point:: 38 °C
Density: 1.693±0.06 g/cm3(Predicted)
refractive index: 1.45
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
form: Oil
color: Clear Colourless
InChI: InChI=1S/C6H4BrF3O/c7-3-4-1-2-5(11-4)6(8,9)10/h1-2H,3H2
InChIKey: YNHVBNGRNNVEMD-UHFFFAOYSA-N
SMILES: O1C(C(F)(F)F)=CC=C1CBr

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Safety

Hazard Codes: C
Risk Statements: 34-36/37/38-43
Safety Statements: 26-36/37/39-45-36/37
RIDADR: 1760
Hazard Note: Corrosive
HazardClass: 8
PackingGroup: Ⅲ
HS Code: 2932190090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B5800
Product name: 2-(Bromomethyl)-5-(trifluoromethyl)furan
Purity: >97.0%(GC)
Packaging: 200mg
Price: $39
Updated: 2025/07/31

TCI Chemical

Product number: B5800
Product name: 2-(Bromomethyl)-5-(trifluoromethyl)furan
Purity: >97.0%(GC)
Packaging: 1g
Price: $156
Updated: 2025/07/31

TRC

Product number: B687925
Product name: 2-(Bromomethyl)-5-(trifluoromethyl)furan
Packaging: 250mg
Price: $80
Updated: 2021/12/16

TRC

Product number: B687925
Product name: 2-(Bromomethyl)-5-(trifluoromethyl)furan
Packaging: 25g
Price: $895
Updated: 2021/12/16

Apolloscientific

Product number: PC2459
Product name: 2-(Bromomethyl)-5-(trifluoromethyl)furan
Purity: 95%
Packaging: 1g
Price: $32
Updated: 2021/12/16

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2-(Bromomethyl)-5-(trifluoromethyl)furan Chemical Properties,Usage,Production

Uses

2-(Bromomethyl)-5-(trifluoromethyl)furan is an intermediate used to prepare tertiary sulfonamides as liver X receptor antagonists. It is also used to synthesize hydantoin based inhibitors of MMP13 with potential use in osteoarthritis.

Synthesis

17515-75-2

17515-77-4

The general procedure for the synthesis of 2-bromomethyl-5-trifluoromethylfuran from 5-methyl-2-trifluoromethylfuran was as follows: to a solution of 2-methyl-5-(trifluoromethyl)furan (4 g, 26.6 mmol) in chloroform (60 mL) was added sequentially N-bromosuccinimide (5.2 g, 29.3 mmol) and 2,2'-azobis(isobutyronitrile) (220 mg 1.33 mmol). The reaction mixture was heated to reflux for 15 minutes. After completion of the reaction, the reaction solution was cooled, poured into water (200 mL) and extracted with chloroform. The organic phases were combined, washed sequentially with water and saturated saline and dried over anhydrous magnesium sulfate. The solvent was concentrated under reduced pressure to give 2-(bromomethyl)-5-(trifluoromethyl)furan (4.79 g, 78% yield). Infrared spectrum of the product (KBr pressed sheet) νmax/cm-1 : 1738, 1688, 1599, 1559. 1H-NMR (CDCl3) δ: 4.46 (2H, s), 6.45 (1H, d, J = 3.8 Hz), 6.75 (1H, d, J = 3.8 Hz).

References

[1] Patent: EP1362846, 2003, A1. Location in patent: Page/Page column 125

2-(Bromomethyl)-5-(trifluoromethyl)furan Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(Bromomethyl)-5-(trifluoromethyl)furan Suppliers

Americas 1 Belgium 1 China 142 Europe 1 Germany 3 India 3 Japan 1 United Kingdom 2 United States 11 Global 165

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View Lastest Price from 2-(Bromomethyl)-5-(trifluoromethyl)furan manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 2-(Bromomethyl)-5-(trifluoromethyl)furan 17515-77-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-14

Career Henan Chemical Co

Product: 2-(Bromomethyl)-5-(trifluoromethyl)furan 17515-77-4
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2018-08-15

Career Henan Chemical Co

Product: 2-(Bromomethyl)-5-(trifluoromethyl)furan 17515-77-4
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KG
Release date: 2018-08-15

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2-(BROMOMETHYL)-5-(TRIFLUOROMETHYL)FURAN

2-(Bromomethyl)-5-(trifluoromethyl)furan 97%

2-(Bromomethyl)-5-(trifluoromethyl)furan97%

2-(Bromomethyl)-5-(trifluoromethyl)furane

Furan,2-(broMoMethyl)-5-(trifluoroMethyl)-

17515-77-4

C6H4BrF3O

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