RAS INHIBITORY PEPTIDE

Product Name: RAS INHIBITORY PEPTIDE
CAS No.: 159088-48-9
Chemical Name: RAS INHIBITORY PEPTIDE
Synonyms: VPPPVPPRRR-NH2;RAS INHIBITORY PEPTIDE;Sos SH3 domain inhibitor;Sos SH3 domain inhibitor inhibitor;VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG;HSOS (1149-1158) N10 SH3 BINDING DOMAIN;H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH;L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-
CBNumber: CB5356014
Molecular Formula: C53H91N19O11
Formula Weight: 1170.41
MOL File: 159088-48-9.mol

More

Less

RAS INHIBITORY PEPTIDE Property

Density: 1.52±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: Miscible; PBS (pH 7.2): 10 mg/ml
form: A crystalline solid
pka: 3.31±0.10(Predicted)

More

Less

Safety

WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 17474
Product name: Ras Inhibitory Peptide
Purity: ≥95%
Packaging: 500μg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 17474
Product name: Ras Inhibitory Peptide
Purity: ≥95%
Packaging: 1mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 17474
Product name: Ras Inhibitory Peptide
Purity: ≥95%
Packaging: 5mg
Price: $502
Updated: 2024/03/01

Cayman Chemical

Product number: 17474
Product name: Ras Inhibitory Peptide
Purity: ≥95%
Packaging: 10mg
Price: $869
Updated: 2024/03/01

Usbiological

Product number: R1198-40
Product name: Ras Inhibitory Peptide
Packaging: 1mg
Price: $531
Updated: 2021/12/16

More

Less

RAS INHIBITORY PEPTIDE Chemical Properties,Usage,Production

Description

Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction that is essential for Ras activation by receptor tyrosine kinases, including epidermal growth factor receptor.

RAS INHIBITORY PEPTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

RAS INHIBITORY PEPTIDE Suppliers

China 32 Germany 1 Japan 1 Switzerland 2 United Kingdom 1 United States 9 USA 1 Global 47

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel
Country: China
ProdList: 42982
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Fax: 0571-87213919
Email: eric@peptidego.com
Country: China
ProdList: 6347
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6870
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19105
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

Hangzhou Go Top Peptide Biotech

Tel: 0571-88211921 13355716090
Email: Sales@gotopbio.com
Country: China
ProdList: 2831
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8141
Advantage: 58

Shaoxing Junyu Biotechnology Co., LTD

Tel: 0571-88211921 15572296305
Email: sales4@gotopbio.com
Country: China
ProdList: 5144
Advantage: 58

159088-48-9, RAS INHIBITORY PEPTIDERelated Search:

H-ORN-ORN-ORN-OH ACOH RAS INHIBITORY PEPTIDE

RAS INHIBITORY PEPTIDE

VPPPVPPRRR-NH2

VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG

H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH

HSOS (1149-1158) N10 SH3 BINDING DOMAIN

Sos SH3 domain inhibitor

L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-

Sos SH3 domain inhibitor inhibitor

159088-48-9

C53H91N19O11

BioChemical

Cell Signaling and Neuroscience

Cell Biology

Reagents

G Protein Function

G Proteins and Cyclic Nucleotides