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RAS INHIBITORY PEPTIDE

Product Name
RAS INHIBITORY PEPTIDE
CAS No.
159088-48-9
Chemical Name
RAS INHIBITORY PEPTIDE
Synonyms
VPPPVPPRRR-NH2;RAS INHIBITORY PEPTIDE;Sos SH3 domain inhibitor;Sos SH3 domain inhibitor inhibitor;VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG;HSOS (1149-1158) N10 SH3 BINDING DOMAIN;H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH;L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-
CBNumber
CB5356014
Molecular Formula
C53H91N19O11
Formula Weight
1170.41
MOL File
159088-48-9.mol
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RAS INHIBITORY PEPTIDE Property

Density 
1.52±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: Miscible; PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
pka
3.31±0.10(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17474
Product name
Ras Inhibitory Peptide
Purity
≥95%
Packaging
500μg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
17474
Product name
Ras Inhibitory Peptide
Purity
≥95%
Packaging
1mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
17474
Product name
Ras Inhibitory Peptide
Purity
≥95%
Packaging
5mg
Price
$502
Updated
2024/03/01
Cayman Chemical
Product number
17474
Product name
Ras Inhibitory Peptide
Purity
≥95%
Packaging
10mg
Price
$869
Updated
2024/03/01
Usbiological
Product number
R1198-40
Product name
Ras Inhibitory Peptide
Packaging
1mg
Price
$531
Updated
2021/12/16
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RAS INHIBITORY PEPTIDE Chemical Properties,Usage,Production

Description

Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction that is essential for Ras activation by receptor tyrosine kinases, including epidermal growth factor receptor.

RAS INHIBITORY PEPTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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RAS INHIBITORY PEPTIDE Suppliers

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303 +86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4844
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Fax
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
6756
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32080
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
0571-88211921 13355716090
Email
Sales@gotopbio.com
Country
China
ProdList
2858
Advantage
58

159088-48-9, RAS INHIBITORY PEPTIDERelated Search:


  • RAS INHIBITORY PEPTIDE
  • VPPPVPPRRR-NH2
  • VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG
  • H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH
  • HSOS (1149-1158) N10 SH3 BINDING DOMAIN
  • Sos SH3 domain inhibitor
  • L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-
  • Sos SH3 domain inhibitor inhibitor
  • 159088-48-9
  • C53H91N19O11
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Reagents
  • G Protein Function
  • G Proteins and Cyclic Nucleotides