ChemicalBook > CAS DataBase List > ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate
ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate
- Product Name
- ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate
- CAS No.
- 300803-69-4
- Chemical Name
- ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate
- Synonyms
- STOML3 inhibitor OB-1;ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate;3-Benzofurancarboxylic acid, 5-[(1-methyl-4-nitro-1H-imidazol-5-yl)oxy]-2-phenyl-, ethyl ester
- CBNumber
- CB53577722
- Molecular Formula
- C21H17N3O6
- Formula Weight
- 407.38
- MOL File
- 300803-69-4.mol
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ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- A solid
- color
- White to off-white
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N-Bromosuccinimide Price
DC Chemicals
- Product number
- 002953
- Product name
- STOML3inhibitorOB-1
- Packaging
- 004
- Price
- $1100
- Updated
- 2021/12/16
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ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate Chemical Properties,Usage,Production
Biological Activity
OB-1 is an inhibitor of the oligomerization of Stomatin-like protein-3 (STOML3), which is a modulator of the mechanosensitive ion channel Piezo2. STOML3 requires oligomerization for its role as an endogenous regulator of the sensitivity of mechanosensitive Piezo ion channels in sensory neurons. By inhibiting this activity, OB-1 has been shown to reduce touch-evoked pain behavior in two mouse models of neuropathic pain.
storage
Store at RT
ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate Suppliers
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