METHYL 3-(ACETYLAMINO)-2-THIOPHENECARBOXYLATE
- Product Name
- METHYL 3-(ACETYLAMINO)-2-THIOPHENECARBOXYLATE
- CAS No.
- 22288-79-5
- Chemical Name
- METHYL 3-(ACETYLAMINO)-2-THIOPHENECARBOXYLATE
- Synonyms
- methyl 3-acetamidothiophene-2-carboxylate;METHYL 3-(ACETYLAMINO)-2-THIOPHENECARBOXYLATE;3-AcetylaMino-thiophene-2-carboxylic acid Methyl ester;2-Thiophenecarboxylic acid, 3-(acetylamino)-, methyl ester
- CBNumber
- CB5358412
- Molecular Formula
- C8H9NO3S
- Formula Weight
- 199.23
- MOL File
- 22288-79-5.mol
METHYL 3-(ACETYLAMINO)-2-THIOPHENECARBOXYLATE Property
- Melting point:
- 94-95°C
- Boiling point:
- 399.9±27.0 °C(Predicted)
- Density
- 1.329±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 14.35±0.70(Predicted)
- Appearance
- White to off-white Crystal
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M293238
- Product name
- Methyl3-Acetamidothiophene-2-carboxylate
- Packaging
- 500mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 1279AB
- Product name
- Methyl3-acetamidothiophene-2-carboxylate
- Packaging
- 1g
- Price
- $113
- Updated
- 2021/12/16
- Product number
- 045025
- Product name
- Methyl 3-(acetylamino)-2-thiophenecarboxylate
- Purity
- >95%
- Packaging
- 500mg
- Price
- $181
- Updated
- 2021/12/16
- Product number
- 045025
- Product name
- Methyl 3-(acetylamino)-2-thiophenecarboxylate
- Purity
- >95%
- Packaging
- 1g
- Price
- $228
- Updated
- 2021/12/16
- Product number
- 045025
- Product name
- Methyl 3-(acetylamino)-2-thiophenecarboxylate
- Purity
- >95%
- Packaging
- 5g
- Price
- $524
- Updated
- 2021/12/16
METHYL 3-(ACETYLAMINO)-2-THIOPHENECARBOXYLATE Chemical Properties,Usage,Production
Synthesis
22288-78-4
75-36-5
22288-79-5
Methyl 3-amino-2-thiophenecarboxylate (3.14 g, 20.0 mmol) was dissolved in pyridine (20 mL) and acetyl chloride (1.5 mL, 21 mmol) was added slowly and dropwise under ice bath cooling conditions. The reaction mixture was stirred at room temperature for 3 hours, then cooled again in an ice bath and supplemented with acetyl chloride (0.3 mL, 4 mmol). Stirring was continued at room temperature for 1.5 h. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure. The resulting solid product was suspended and washed with water to give the final methyl 3-acetylaminothiophene-2-carboxylate (3.80 g, 19.1 mmol, 96% yield).
References
[1] Patent: JP2018/95564, 2018, A. Location in patent: Paragraph 0097-0099
[2] European Journal of Medicinal Chemistry, 2014, vol. 85, p. 215 - 227
[3] Patent: US2008/4325, 2008, A1. Location in patent: Page/Page column 18
[4] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 1, p. 9 - 12
METHYL 3-(ACETYLAMINO)-2-THIOPHENECARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL 3-(ACETYLAMINO)-2-THIOPHENECARBOXYLATE Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11032
- Advantage
- 64
- Tel
- 0531-81313138 13066006660
- Fax
- QQ: 3366077777
- chibapharm@foxmail.com
- Country
- China
- ProdList
- 3953
- Advantage
- 55
- Tel
- 86-21-34053660
- Fax
- 86-21-34053661
- sale@labgogo.com
- Country
- China
- ProdList
- 9865
- Advantage
- 52
- Tel
- 18652989687
- Fax
- +86-25-52131256
- sales@norris-pharm.com
- Country
- China
- ProdList
- 8878
- Advantage
- 55
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9341
- Advantage
- 55
- Tel
- 86(512)5235 8471 17715136450
- Fax
- 86(512)5235 6881
- sales@shiyabiopharm.com
- Country
- China
- ProdList
- 4169
- Advantage
- 58
- Tel
- +1(858) 699-3322
- Fax
- +1(858) 876-1948
- marketing@accelachem.com
- Country
- United States
- ProdList
- 6024
- Advantage
- 65