Sodium (S)-lactate

Product Name: Sodium (S)-lactate
CAS No.: 867-56-1
Chemical Name: Sodium (S)-lactate
Synonyms: SODIUM L-LACTATE;Sodium (S)-2-hydroxypropanoate;SODIUM L-LACTATE SOLUTION;L-Sodium;Sodium (S);PURASAL(R)S;SodiuM Lactate(60%);L-SODIUM LACTATE;SodiuM L-LaCLate
CBNumber: CB5359015
Molecular Formula: C3H7NaO3
Formula Weight: 114.08
MOL File: 867-56-1.mol

More

Less

Sodium (S)-lactate Property

Melting point:: 163-165 °C (lit.)
Boiling point:: 115℃[at 101 325 Pa]
Density: 1.33
refractive index: 1,422-1,425
storage temp.: 2-8°C
solubility: Aqueous Base (Sparingly), Water (Sparingly)
form: Powder
color: White to yellow
Odor: Odorless
biological source: synthetic (chemical)
optical activity: [α]20/D 12.5±0.5°, c = 1% in H2O
Water Solubility: soluble
Sensitive: Hygroscopic
BRN: 4567087
Stability:: Hygroscopic
LogP: -1.52 at 20℃
CAS DataBase Reference: 867-56-1(CAS DataBase Reference)
EPA Substance Registry System: Propanoic acid, 2-hydroxy-, monosodium salt, (2S)- (867-56-1)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 24/25-36-26
WGK Germany: 1
F: 3-10
TSCA: Yes
HS Code: 29181100

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 71718
Product name: Sodium L-lactate
Purity: ≥99.0% (NT)
Packaging: 1kg
Price: $3569.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1614308
Product name: Sodium lactate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $467
Updated: 2025/07/31

Sigma-Aldrich

Product number: L7022
Product name: Sodium L-lactate
Purity: ~98%
Packaging: 5g
Price: $102
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHR1113
Product name: Sodium L-lactate
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 1g
Price: $105
Updated: 2025/07/31

Sigma-Aldrich

Product number: L7022
Product name: Sodium L-lactate
Purity: ~98%
Packaging: 10g
Price: $149
Updated: 2025/07/31

More

Less

Sodium (S)-lactate Chemical Properties,Usage,Production

Chemical Properties

clear viscous liquid

Uses

Sodium L-lactate is used as a food additive, preservative, acidity regulator and bulking agent. It finds application in shampoo and liquid soaps and other related products. It acts as an effective humectant and moisturizer. It is used in the treatment of arrhythmias.

General Description

Sodium L-lactate is an alkalinizing compound, currently being researched for its efficacy in the treatment of acidosis.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

L-lactate is produced from pyruvate by the enzyme lactate dehydrogenase. Lactate production occurs during anaerobic glycolysis or in proliferatively active cells.

Synthesis

923031-01-0

923031-02-1

2216-51-5

867-56-1

61597-98-6

The general procedure for the synthesis of L-menthol, sodium L-lactate and (S)-(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 2-hydroxypropionate from compound (CAS:923031-01-0) and compound (CAS:923031-02-1) is as follows: 1. Preparation of L-lactic acid L-menthyl ester (ML) by esterification reaction: - In a three-necked flask equipped with a Barrett trap, reflux condenser, thermocouple, heating jacket and magnetic stirrer, L-menthol (1440 g), L-(+)-lactic acid (2880 g, an aqueous solution of 88% lactic acid from Purac, HS-88 grade) and heptane (720 g) were added. - The mixture was stirred and refluxed and the resulting water was periodically drained from the trap. - After 32 hours, the reaction was stopped when 854 mL of the aqueous phase was collected and the temperature of the mixture rose to 128 °C. The reaction was stopped by a gas chromatograph. - After cooling to room temperature, the reaction mixture was analyzed by gas-liquid chromatography (GC), which showed the presence of 5.4% unreacted menthol, 67.7% ML, 0.6% propanedioate, 24.6% L-lactoyl-L-lactide (MLL), and 4-butyl L-lactoyl-L-lactoyl-L-lactic acid (MLLL). 2. Controlled hydrolysis: - Dilute the esterified product with water (4230 g) and heptane (960 g). - A 50% aqueous sodium hydroxide solution (809 g) was added dropwise over 30 minutes while stirring and cooling (cold water bath), keeping the temperature not exceeding 30 °C and pH not exceeding 12.9. - After the dropwise addition, stirring was continued for 20 min. the GC analysis showed almost complete conversion of MLL to ML. - The organic layer was separated and washed with 1.5% aqueous lactic acid (1000 g) and azeotroped to remove water. - The solvent (heptane) was evaporated and the residue was fractionated under vacuum to give three fractions: fraction 1 (100 g, 94.5% menthol and 2.0% ML), fraction 2 (111 g, 46.8% menthol and 51.8% ML), and fraction 3 (1860 g, 99.5% pure ML). - The overall yield of ML was 91% based on the initial menthol, and the yield of purified ML was 98% based on the reacted menthol. 3. Sulfuric acid-catalyzed esterification and controlled hydrolysis: - The esterification reaction was carried out using L-menthol (1000 g), L-(+)-lactic acid (1000 g), heptane (500 g) and concentrated sulfuric acid (6 g). - After 2 hours, 300mL of the aqueous phase was collected and the temperature of the mixture was raised to 119°C. - After cooling GC analysis showed the presence of 6.4% unreacted menthol, 57.6% ML, 0.4% propylenol, 32.2% MLL and 1.9% MLLL. - The controlled hydrolysis step was performed with water (800 g) and heptane (500 mL) to dilute the esterification product, and 50% aqueous sodium hydroxide (204 g) was added dropwise over 70 min, keeping the temperature to no more than 30 °C and the pH to no more than 13.1. - The organic layer was separated and further diluted with water (1350 g) and 50% aqueous sodium hydroxide solution (150 g) was added dropwise over 1 hour. - After stirring for 1 h, GC analysis showed almost complete conversion of MLL to ML. - The organic layers were separated, washed and combined, the solvents were evaporated, and vacuum fractionation yielded three fractions: fraction 1 (203 g, 87.1% menthol, 3.5% ML, and 6.2% menthol), fraction 2 (96.8 g, 57.2% menthol and 41.6% ML), and fraction 3 (2356 g, 99.4% pure ML). - The overall yield of ML was 81% based on the initial menthol, and the yield of purified ML was 91% based on the reacted menthol. 4. Controlled hydrolysis (normal addition mode): - In a 500-mL flask, crude ML (88.7 g) was mixed with water (89 g) and heptane (20 g) at a constant temperature to the test temperature. - Under stirring, 50% aqueous sodium hydroxide (35.5 g) was added gradually over 0.6-3.6 h. The pH was recorded periodically. - After the addition was completed, stirring was done until the GC peak of the MLL dropped below 1%. 5. Reverse addition: - A 50% aqueous sodium hydroxide solution (35.5 g) was added to a 500-mL flask and thermostated to the test temperature. - The esterification mixture was gradually added to the aqueous alkali solution with stirring and the pH change was recorded. - This method is not effective at pH 14 or above.

References

[1] Patent: US7173146, 2007, B1. Location in patent: Page/Page column 5-8

Sodium (S)-lactate Preparation Products And Raw materials

Raw materials

L(+)-Lactic acid Sodium hydroxide Lactic acid

Preparation Products

Ferrous lactate

More

Less

Sodium (S)-lactate Suppliers

Belgium 2 China 350 Europe 3 Germany 5 India 5 Japan 2 Switzerland 1 United Kingdom 5 United States 19 USA 1 Global 393

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10648
Advantage: 60

Alfa Chemistry

Tel: 1-516-6625404
Fax: 1-516-927-0118
Email: support@alfa-chemistry.com
Country: United States
ProdList: 9171
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39035
Advantage: 58

Aceschem Inc.

Tel: +1-817863-6948 +1-（817）863-6948
Email: sales@aceschem.com
Country: United States
ProdList: 19632
Advantage: 58

United States Biological

Tel: --
Fax: --
Email: sales@advtechind.com
Country: United States
ProdList: 6075
Advantage: 58

AppliChem, LLC

Tel: --
Fax: --
Email: sales@applichem.com
Country: United States
ProdList: 169
Advantage: 50

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: United States
ProdList: 6814
Advantage: 81

HBCChem Inc.

Tel: --
Fax: --
Email: sales@hbcchem-inc.com
Country: United States
ProdList: 4569
Advantage: 30

Glentham Life Sciences Ltd

Tel: --
Fax: --
Email: info@glentham.com
Country: United States
ProdList: 2026
Advantage: 58

ECSA Chemicals

Tel: --
Fax: --
Email: marketing@ecsa.ch
Country: United States
ProdList: 1735
Advantage: 58

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

Cambridge Isotope Laboratories, Inc.

Tel: --
Fax: --
Email: cilsales@isotope.com
Country: United States
ProdList: 6598
Advantage: 79

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Spectrum Chemicals & Laboratory Products

Tel: --
Fax: --
Email: sales@spectrumchemical.com
Country: United States
ProdList: 6699
Advantage: 77

APAC Pharmaceutical, LLC

Tel: --
Fax: --
Email: sales@apacpharma.com
Country: United States
ProdList: 6322
Advantage: 38

Medical Isotopes

Tel: --
Fax: --
Email: stohler@medicalisotopes.com
Country: United States
ProdList: 6181
Advantage: 68

More

Less

View Lastest Price from Sodium (S)-lactate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Sodium (S)-lactate 867-56-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2025-03-13

HebeiShuoshengImportandExportco.,Ltd

Product: Sodium (S)-lactate 867-56-1
Price: US $6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000KG/Month
Release date: 2024-08-06

Hebei Chuanghai Biotechnology Co., Ltd

Product: Sodium (S)-lactate 867-56-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-04

867-56-1, Sodium (S)-lactateRelated Search:

Lactic acid Sodium benzoate Sodium chloride Sodium bicarbonate Sodium hydroxide Ethyl 2-(Chlorosulfonyl)acetate Sodium gluconate Sodium acetate Folic acid 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Ascoric Acid SODIUM-DL-LACTATE, 70 WT% AQUEOUS SOLUTION,Sodium DL-lactate, 60% w/w aq. soln.,SODIUM DL-LACTATE,SODIUM DL-LACTATE SOLUTION Sodium stearyl lactate Sodium danshensu SODIUM L-LACTATE,SODIUM L-LACTATE SOLUTION aluminium-sodium chlorohydroxy lactate SODIUM LACTATE METHYLSILANOL SODIUM STEAROYL LACTATE,sodium stearoyl lactate(SSL)

L-Lactic acid sodium salt, Extra Pure

2-hydroxy-,monosodiumsalt,(s)-propanoicaci

(S)-2-HYDROXYPROPIONIC ACID SODIUM SALT

SARCOLACTIC ACID SODIUM SALT

S-LACTIC ACID SODIUM SALT

SODIUM-L-2-HYDROXY-PROPIONATE

SODIUM L-LACTATE

SODIUM L-LACTATE SOLUTION

PURASAL(R)S

PURASAL(R)S/HQ 60

PURASAL(R)S/PF 60

PURASAL(R)S/SP 60

L(+) LACTIC ACID, SODIUM SALT

L-LACTIC ACID SODIUM SALT

L-LACTIC ACID NA-SALT

L-SODIUM LACTATE

2-HYDROXYPROPANOIC ACID MONOSODIUM SALT

L(+)LACTIC ACID SODIUM

L-LACTIC ACID SODIUM SALT, 40% SOLUTION IN WATER

SodiumL-lactate,98+%

L-Lactic acid, sodium salt, 60 wt% solution in water

Sodium Lactate-1-13C

L-Sodium

Lactic acid-Na-salt

Natrium-(S)-lactat

Sodium (S)-lactate

(S)-2-Hydroxypropionic acid sodium salt, L-Lactic acid sodium salt, Sarcolactic acid sodium salt

(2S)-2-Hydroxypropanoic acid sodium salt

(S)-2-Hydroxypropanoic acid sodium salt

SodiuM L-LaCLate

L-Lactic acid sodiuM salt, 99%, extra pure

(S)-2-Hydroxypropanoic acid monosodium salt

L-Lactic acid, sodiuM salt, 60 wt% solution in water 1LT

L-LACTIC ACID.NA-SALT CRYST.RESEARCH GRADE

Sodium L-lactate,(S)-2-Hydroxypropionic acid sodium salt, L-Lactic acid sodium salt, Sarcolactic acid sodium salt

Sodium lactate, solution 50%, extra pure, Ph Eur, USP, BP, E 325

Sodium Lactate (200 mg)

Sodium Lactate (200 mg)J0E2491.000mg/mg(dr)

Lactate(60%)

SodiuM&nbsp

SodiuM L-lactate solution,60% in water

Lactic acid-Na-salt cryst. research grade

Propanoic acid,2-hydroxy-, sodiuM salt (1:1), (2S)-

SodiuM L-lactate >=99.0% (NT)

Sodium (L) lactate 60% solution

Sodium (S)-2-hydroxypropanoate

Sodium (S)

Sodium L-Lactate Solution (about 50%)

Sodium L-Lactate Solution (about 70%)

Sodium (S)-lactate ISO 9001：2015 REACH

sodium laevo-lactate

Sulfolane 126-33-0

Sodium L-lactate solution (50mM, pH4.0)

Nicotinamide Impurity 6-d3 (Nedifloramide-d3)

high qualtiy Sodium (S)-Lactate

(L)-Sodium lactate, 10 mM in DMSO

Sodium <sc>L</sc>-lactate

Sodium L-lactate - 60% aqueous solution