4-AMINO-2,3-DIFLUORO-PHENOL
- Product Name
- 4-AMINO-2,3-DIFLUORO-PHENOL
- CAS No.
- 163733-99-1
- Chemical Name
- 4-AMINO-2,3-DIFLUORO-PHENOL
- Synonyms
- 4-AMINO-2,3-DIFLUORO-PHENOL;2,3-DIFLUORO-4-HYDROXYANILINE;Phenol, 4-amino-2,3-difluoro-;4-Amino-2,3-difluorophenol,98%;Phenol, 4-amino-2,3-difluoro- (9CI);4-AMINO-2,3-DIFLUORO-PHENOL ISO 9001：2015 REACH
- CBNumber
- CB5360439
- Molecular Formula
- C6H5F2NO
- Formula Weight
- 145.11
- MOL File
- 163733-99-1.mol
4-AMINO-2,3-DIFLUORO-PHENOL Property
- Melting point:
- ca 153℃
- Boiling point:
- 255.5±40.0 °C(Predicted)
- Density
- 1.472±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- form
- powder
- pka
- 7.99±0.23(Predicted)
- color
- Black
Safety
- Hazard Codes
- Xi
- RIDADR
- UN2928
- Hazard Note
- Irritant
- HazardClass
- 6.1, 8
- HS Code
- 2908990000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A576615
- Product name
- 4-Amino-2,3-difluorophenol
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 4656-3-Z6
- Product name
- 4-Amino-2,3-difluorophenol
- Packaging
- 100mg
- Price
- $132
- Updated
- 2021/12/16
- Product number
- 4656-3-Z6
- Product name
- 4-Amino-2,3-difluorophenol
- Packaging
- 1g
- Price
- $168
- Updated
- 2021/12/16
- Product number
- X0246
- Product name
- 4-Amino-2,3-difluoro-Phenol
- Packaging
- 5g
- Price
- $504
- Updated
- 2021/12/16
- Product number
- 4656-3-Z6
- Product name
- 4-Amino-2,3-difluorophenol
- Packaging
- 5G
- Price
- $600
- Updated
- 2021/12/16
4-AMINO-2,3-DIFLUORO-PHENOL Chemical Properties,Usage,Production
Chemical Properties
brown toblack powde
Uses
4-Amino-2,3-difluorophenol is one of the 4-aminophenol metabolites used to study dehalogenation.
Synthesis
868735-81-3
163733-99-1
Under hydrogen atmosphere (30 psi), 1-benzyloxy-2,3-difluoro-4-nitrobenzene (14 g, 52.8 mmol) was dissolved in methanol (200 mL), 10% Pd/C catalyst (1.4 g, 1.3 mmol) was added, and the reaction was stirred for 2 hours. After completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated in vacuum to afford 4-amino-2,3-difluorophenol (7 g, 92% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 9.05 (s, 1H), 6.45 (t, J = 8.8 Hz, 1H), 6.34 (t, J = 9.2 Hz, 1H), 4.67 (s, 2H); Mass Spectra (ESI) m/z: 146.1 [M + H]+.
References
[1] Patent: US2008/90856, 2008, A1. Location in patent: Page/Page column 41
[2] Patent: WO2010/51373, 2010, A1. Location in patent: Page/Page column 61
[3] Patent: WO2013/36232, 2013, A2. Location in patent: Paragraph 00279
[4] Patent: WO2013/180949, 2013, A1. Location in patent: Paragraph 0180
[5] Patent: WO2014/22116, 2014, A2. Location in patent: Paragraph 0177
4-AMINO-2,3-DIFLUORO-PHENOL Preparation Products And Raw materials
Raw materials
Preparation Products
4-AMINO-2,3-DIFLUORO-PHENOL Suppliers
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
View Lastest Price from 4-AMINO-2,3-DIFLUORO-PHENOL manufacturers
- Product
- 4-Amino-2,3-difluorophenol 163733-99-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- Min98% HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2020-01-29