16,16-DIMETHYL PROSTAGLANDIN F2ALPHA

Product Name: 16,16-DIMETHYL PROSTAGLANDIN F2ALPHA
CAS No.: 39746-23-1
Chemical Name: 16,16-DIMETHYL PROSTAGLANDIN F2ALPHA
Synonyms: YMRWVEHSLXJOCD-SCOYTADVSA-N;16,16-dimethylprostaglandin F2A;16,16-dimethyl Prostaglandin F2α;16,16-DIMETHYL PROSTAGLANDIN F2ALPHA;9ALPHA,11ALPHA,15R-TRIHYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID;Prosta-5,13-dien-1-oicacid, 9,11,15-trihydroxy-16,16-dimethyl-, (5Z,9a,11a,13E,15R)- (9CI)
CBNumber: CB5361254
Molecular Formula: C22H38O5
Formula Weight: 382.53
MOL File: 39746-23-1.mol

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16,16-DIMETHYL PROSTAGLANDIN F2ALPHA Property

Flash point:: -13 °C
storage temp.: -20°C
solubility: 10 mM Na2CO3: >6.5 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: >100 mg/ml; PBS pH 7.2: >10 mg/ml
form: A crystalline solid

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Safety

Hazard Codes: F,Xi
Risk Statements: 11-36-66-67
Safety Statements: 16-26-29-33

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16750
Product name: 16,16-dimethyl Prostaglandin F2α
Purity: ≥98%
Packaging: 1mg
Price: $82
Updated: 2024/03/01

Cayman Chemical

Product number: 16750
Product name: 16,16-dimethyl Prostaglandin F2α
Purity: ≥98%
Packaging: 5mg
Price: $362
Updated: 2024/03/01

Cayman Chemical

Product number: 16750
Product name: 16,16-dimethyl Prostaglandin F2α
Purity: ≥98%
Packaging: 10mg
Price: $642
Updated: 2024/03/01

AK Scientific

Product number: 1253AH
Product name: 16,16-DimethylprostaglandinF2alpha
Packaging: 10mg
Price: $812
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0005982
Product name: 16,16-DIMETHYL PROSTAGLANDIN F2ALPHA
Purity: 95.00%
Packaging: 5MG
Price: $497.95
Updated: 2021/12/16

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16,16-DIMETHYL PROSTAGLANDIN F2ALPHA Chemical Properties,Usage,Production

Uses

16,16-Dimethylprostaglandin F2α (16,16-Dimethyl-PGF2α) is a potent analog of PGF2α (HY-12956), which exhibits similar binding potency as PGF2α does. 16,16-Dimethylprostaglandin F2α serves as a bronchoconstrictor[1][2].

in vivo

16,16-Dimethylprostaglandin F2α (0-0.5 μg, iv, single dose) inhibits histamine-induced intracheal insufflation pressure increase in guinea pigs model.

Animal Model:	guinea pigs model^[1]
Dosage:	0-0.5 μg
Administration:	iv, single dose
Result:	Inhibited histamine-induced increase in tracheal insufflation pressure.

References

[1] Strandberg K, et al., Bronchial effects of some prostaglandin E and F analogues. Acta Physiol Scand. 1977 Jun;100(2):172-81. DOI:10.1111/j.1748-1716.1977.tb05934.x
[2] Balapure AK, et al., Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe. Biochem Pharmacol. 1989 Jul 15;38(14):2375-81. DOI:10.1016/0006-2952(89)90478-4

16,16-DIMETHYL PROSTAGLANDIN F2ALPHA Preparation Products And Raw materials

Raw materials

Preparation Products

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16,16-DIMETHYL PROSTAGLANDIN F2ALPHA Suppliers

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39746-23-1, 16,16-DIMETHYL PROSTAGLANDIN F2ALPHARelated Search:

1,9ALPHA, 11ALPHA, 15S-TETRAHYDROXYPROSTA-5Z, 13E-DIENE 16,16-DIMETHYL PROSTAGLANDIN F2ALPHA 11-DEOXY PROSTAGLANDIN F2ALPHA Dinoprost tromethamine (+-)-PGF2-alpha

16,16-DIMETHYL PROSTAGLANDIN F2ALPHA

9ALPHA,11ALPHA,15R-TRIHYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID

16,16-dimethylprostaglandin F2A

16,16-dimethyl Prostaglandin F2α

YMRWVEHSLXJOCD-SCOYTADVSA-N

Prosta-5,13-dien-1-oicacid, 9,11,15-trihydroxy-16,16-dimethyl-, (5Z,9a,11a,13E,15R)- (9CI)

39746-23-1