ChemicalBook > CAS DataBase List > 4'-CHLOROPIVALOANILIDE

4'-CHLOROPIVALOANILIDE

Product Name
4'-CHLOROPIVALOANILIDE
CAS No.
65854-91-3
Chemical Name
4'-CHLOROPIVALOANILIDE
Synonyms
4-Chloropivalamide;4-Chloropivalanilide;4'-CHLOROPIVALOANILIDE;N-Pivaloyl-p-chlorophenyl;4'-Chloropivaloanilide>4-CHLORO-N-PIVALOYLANILINE;N-PIVALOYL-P-CHLOROANILINE;N-(4-chlorophenyl)pivalaMide;N-(4-CHLOROPHENYL)PIVALOYLAMIDE;4''-CHLOROPIVALOANILIDE,98.0%+(GC)
CBNumber
CB5365717
Molecular Formula
C11H14ClNO
Formula Weight
211.69
MOL File
65854-91-3.mol
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4'-CHLOROPIVALOANILIDE Property

Melting point:
152 °C
Boiling point:
352.1±25.0 °C(Predicted)
Density 
1.150±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
14.25±0.70(Predicted)
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Safety

HS Code 
2921420090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S902640
Product name
4'-CHLORO-2,2-DIMETHYLPROPIONANILIDE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$30.7
Updated
2025/07/31
Sigma-Aldrich
Product number
S902640
Product name
4'-CHLORO-2,2-DIMETHYLPROPIONANILIDE
Purity
Aldrich
Packaging
50mg
Price
$29.8
Updated
2024/03/01
TCI Chemical
Product number
C2099
Product name
4'-Chloropivaloanilide
Purity
>98.0%(GC)
Packaging
25g
Price
$31
Updated
2025/07/31
TCI Chemical
Product number
C2099
Product name
4'-Chloropivaloanilide
Purity
>98.0%(GC)
Packaging
250g
Price
$312
Updated
2025/07/31
AK Scientific
Product number
J56537
Product name
4'-Chloropivaloanilide
Packaging
5g
Price
$49
Updated
2021/12/16
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4'-CHLOROPIVALOANILIDE Chemical Properties,Usage,Production

Synthesis

3282-30-2

106-47-8

65854-91-3

The general procedure for synthesizing N-pivaloyl-p-chloroaniline from pivaloyl chloride and 4-chloroaniline was as follows: referring to Example 2, 4-chloroaniline (113 kg, 886 mol), deionized water (565 L), and sodium bicarbonate (89.3 kg, 1.2 eq.) were added to ethyl acetate (1695 L). Pivaloyl chloride (112 kg, 1.05 eq.) was slowly added dropwise at 15°C or lower. After the dropwise addition was completed, the reaction solution was stirred at about 25°C for 2 hours. Upon completion of the reaction, the organic and aqueous layers were separated. The organic layer was washed twice with deionized water (848 L x 2) and then concentrated under reduced pressure to about 600 L. To the concentrate was added ethylcyclohexane (848 L) and again concentrated under reduced pressure to about 600 L. The residue was cooled to about 5 °C and stirred for 1 h to promote crystallization. The precipitated crystals were collected by filtration and dried under reduced pressure to afford N-pivaloyl-p-chloroaniline (187 kg, 99.7% yield).

References

[1] Patent: WO2005/121133, 2005, A1. Location in patent: Page/Page column 30-31
[2] Patent: US2009/247766, 2009, A1. Location in patent: Page/Page column 27
[3] Patent: WO2015/118515, 2015, A1. Location in patent: Page/Page column 9
[4] Journal of Organic Chemistry, 1998, vol. 63, # 23, p. 8536 - 8543
[5] Patent: CN105801442, 2016, A. Location in patent: Paragraph 0006; 0018; 0022; 0026; 0030

4'-CHLOROPIVALOANILIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4'-CHLOROPIVALOANILIDE manufacturers

Career Henan Chemical Co
Product
4'-CHLOROPIVALOANILIDE 65854-91-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-11

65854-91-3, 4'-CHLOROPIVALOANILIDERelated Search:


  • N-PIVALOYL-P-CHLOROANILINE
  • N-(4-CHLOROPHENYL)-2,2-DIMETHYLPROPIONAMIDE
  • N-(4-CHLOROPHENYL)PIVALOYLAMIDE
  • 4-Chloropivalanilide
  • 4''-CHLOROPIVALOANILIDE,98.0%+(GC)
  • N-Pivaloyl-p-chlorophenyl
  • 4-CHLORO-N-PIVALOYLANILINE
  • 4'-CHLOROPIVALOANILIDE
  • N-(4-Chlorophenyl)-2,2-dimethylpropanamide
  • 4-Chloro-N-pivaloylaniline N-(4-Chlorophenyl)pivaloylamide N-(4-Chlorophenyl)-2,2-dimethylpropionamide
  • N-(4-chlorophenyl)pivalaMide
  • 4'-CHLORO-2,2-DIMETHYLPROPIONANILIDE
  • 4-Chloropivalamide
  • 4'-Chloropivaloanilide&gt
  • Propanamide, N-(4-chlorophenyl)-2,2-dimethyl-
  • 4'-CHLORO-2,2-DIMETHYLPROPIONANILIDE
  • 4′-Chloropivaloanilide, CAS 65854-91-3
  • 65854-91-3