ChemicalBook > CAS DataBase List > 3,6-DIOXA-1,8-OCTANEDITHIOL

3,6-DIOXA-1,8-OCTANEDITHIOL

Product Name
3,6-DIOXA-1,8-OCTANEDITHIOL
CAS No.
14970-87-7
Chemical Name
3,6-DIOXA-1,8-OCTANEDITHIOL
Synonyms
1,8-DIMERCAPTO-3,6-DIOXAOCTANE;2,2’-(ethylenedioxy)diethanethiol;SH-PEG2-SH;Triglycoldimercaptan;3,6-dioxa-1,8-octandithiol;3,6-dioxy-1,8-octyldithiol;3,6-DIOXA-1,8-OCTANEDITHIO;3,6-DIOXA-1,8-OCTANEDITHIOL;3,6-Dioxa-1,8-OCLanedithiol;Triethyleneglycol dimrcaptan
CBNumber
CB5379455
Molecular Formula
C6H14O2S2
Formula Weight
182.3
MOL File
14970-87-7.mol
More
Less

3,6-DIOXA-1,8-OCTANEDITHIOL Property

Boiling point:
225 °C(lit.)
Density 
1.12 g/mL at 25 °C(lit.)
vapor pressure 
0.39Pa at 20℃
refractive index 
n20/D 1.509(lit.)
Flash point:
132 °C
solubility 
Slightly soluble in water
form 
clear liquid
pka
9.34±0.10(Predicted)
color 
Colorless to Light yellow to Light orange
Water Solubility 
11.4g/L at 19.8℃
BRN 
1901671
InChI
InChI=1S/C6H14O2S2/c9-5-3-7-1-2-8-4-6-10/h9-10H,1-6H2
InChIKey
HCZMHWVFVZAHCR-UHFFFAOYSA-N
SMILES
C(OCCS)COCCS
LogP
1.6 at 55℃
CAS DataBase Reference
14970-87-7(CAS DataBase Reference)
EPA Substance Registry System
Ethanethiol, 2,2'-[1,2-ethanediylbis(oxy)]bis- (14970-87-7)
More
Less

Safety

Hazard Codes 
T,N,Xn
Risk Statements 
22-23-36/37/38-51/53-20/22
Safety Statements 
26-45-61
RIDADR 
UN 2810 6.1/PG 3
WGK Germany 
2
HS Code 
29309090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H332Harmful if inhaled

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
465178
Product name
2,2′-(Ethylenedioxy)diethanethiol
Purity
95%
Packaging
100ml
Price
$46.4
Updated
2024/03/01
Sigma-Aldrich
Product number
465178
Product name
2,2′-(Ethylenedioxy)diethanethiol
Purity
95%
Packaging
500ml
Price
$137.6
Updated
2024/03/01
TCI Chemical
Product number
D2649
Product name
3,6-Dioxa-1,8-octanedithiol
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$23
Updated
2024/03/01
TCI Chemical
Product number
D2649
Product name
3,6-Dioxa-1,8-octanedithiol
Purity
>97.0%(GC)(T)
Packaging
100g
Price
$66
Updated
2024/03/01
TCI Chemical
Product number
D2649
Product name
3,6-Dioxa-1,8-octanedithiol
Purity
>97.0%(GC)(T)
Packaging
500g
Price
$198
Updated
2024/03/01
More
Less

3,6-DIOXA-1,8-OCTANEDITHIOL Chemical Properties,Usage,Production

Uses

3,6-dioxa-1,8-octanedithiol (DODT) was used for cleaving peptides in the study to develop synthetic peptide serology to treat chronic chagas disease. DODT may be used to develop non-malodorous scavenger in Fmoc-based peptide synthesis.

Definition

3,6-dioxa-1,8-octanedithiol is a dithiol monomer. This compound could be chosen as a model compound for the active sites of thioredoxins to study its reactions with cis-[Pt(NH3)2Cl4] and trans-[PtCl2(CN)4]2– (cisplatin prodrug and a model complex). The pKa values for the dithiol were characterized to be 8.7 ± 0.2 and 9.6 ± 0.2 at 25.0 °C and an ionic strength of 1.0 M. Triethylamine (TEA) and dilute H2O2 could catalyze the new Radical Ring-opening Redox Polymerization (R3P) of 3,6-dioxa-1,8-octanedithiol[1-2].

Synthesis Reference(s)

The Journal of Organic Chemistry, 33, p. 1275, 1968 DOI: 10.1021/jo01267a089
Triglycol dimercaptan

General Description

3,6-dioxa-1,8-octanedithiol is non volatile in nature.

References

[1] DONGYING MA. Formation of peptide disulfide bonds through a trans-dibromido-Pt(IV) complex oxidation reaction: Kinetic and mechanistic analyses[J]. Journal of Molecular Liquids, 2021. DOI:10.1016/j.molliq.2020.115195.
[2] ROSENTHAL-KIMEMILY Q PuskasJudit E. Green polymer chemistry: investigating the mechanism of radical ring-opening redox polymerization (R3P) of 3,6-dioxa-1,8-octanedithiol (DODT).[J]. Molecules, 2015. DOI:10.3390/molecules20046504.

3,6-DIOXA-1,8-OCTANEDITHIOL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3,6-DIOXA-1,8-OCTANEDITHIOL Suppliers

Americas 1 Chile 1 China 131 Europe 1 France 1 Germany 3 India 4 Japan 4 Slovakia 1 South Korea 1 Switzerland 1 United Kingdom 3 United States 8 Global 160
Jinan Winsor Pharmaceutical Co., Ltd
Tel
152-64160071 15318402391
Fax
QQ：1790106626
Email
1615850970@qq.com
Country
China
ProdList
489
Advantage
58
Shanghai Gugang New Materials Technology Co. Ltd.
Tel
021-51317962
Fax
021-51317962
Email
296935822@qq.com
Country
China
ProdList
974
Advantage
58
Forsman Scientific ( Beijing ) Co., Ltd.
Tel
13811783941 18611317957
Fax
+86-10-64646568
Email
linwp@forsman.com.cn
Country
China
ProdList
851
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3991
Advantage
60
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Tongling HengYou Biotechnology Co., Ltd.
Tel
021-50426030 13856289449
Fax
021-50426030
Email
2630597085@qq.com
Country
China
ProdList
1889
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Cangzhou Enke Pharma-tech Co., Ltd.
Tel
0317-5296180 15533709196
Fax
0317-5106596
Email
sale@enkepharma.com
Country
China
ProdList
1900
Advantage
55
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Taian Jiaye Biotechnology Co.Ltd
Tel
13127280945
Email
285424065@qq.com
Country
China
ProdList
9976
Advantage
55
Guangzhou Jhd Chemical Reagent Co., Ltd.
Tel
020-84383047
Fax
020-84380294
Email
sales@jhd.com.cn
Country
China
ProdList
9186
Advantage
65
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
9998
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19800
Advantage
60
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17987
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
15497
Advantage
58
Shanghai He Huan Chemical Co., Ltd.
Tel
021-60345187 13917602471
Fax
021-60345187
Email
lzz841106@aliyun.com
Country
China
ProdList
9897
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 18016230971
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
24969
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6038 18902104717
Email
sales@heowns.com
Country
China
ProdList
21074
Advantage
60
Jiaxing Nova Chemical Co., Ltd.
Tel
021-20921617 18957373295
Fax
021-20921617
Email
2240425080@qq.com
Country
China
ProdList
891
Advantage
58
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Beijing OKA biological technology co., LTD
Tel
010-010-010-62971590 18548936886
Fax
010-62340519
Email
jack@oka-vip.com
Country
China
ProdList
6897
Advantage
58
Hubei Chusheng Chemical Co., Ltd.
Tel
027-87891008 18971624303
Fax
027-87892127
Email
1569406342@qq.com
Country
China
ProdList
267
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
10057
Advantage
58
Beijing Minruida Technology Co., Ltd.
Tel
010-82387566 18001021521;
Fax
82387566-801
Email
sales@mreda.com.cn
Country
China
ProdList
10789
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57401
Advantage
58
Henan Alpha Chemical Co., Ltd.
Tel
0371-0371-55055611 18137792234
Fax
QQ：3002694073
Email
3002694073@qq.com
Country
China
ProdList
10565
Advantage
58
Shanghai Dingfen Chemical Technology Co., Ltd.
Tel
021-37590756
Fax
021-57450128
Email
373600283@qq.com
Country
China
ProdList
4995
Advantage
58
Hebei Chuanghai Biotechnology Co,.LTD
Tel
+86-13131129325
Fax
86-0311-66562153
Email
sales1@chuanghaibio.com
Country
China
ProdList
5893
Advantage
58
Shandong Believe Chemical PTE.LTD
Tel
+86-18553607090 +8618553607090
Email
1093908296@qq.com
Country
China
ProdList
1667
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34553
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52849
Advantage
58
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
chemwill_asia@126.com
Country
CHINA
ProdList
23912
Advantage
58
Hubei xin bonus chemical co. LTD
Tel
86-13657291602
Fax
027-59338440
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
22963
Advantage
58
More
Less

View Lastest Price from 3,6-DIOXA-1,8-OCTANEDITHIOL manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
3,6-DIOXA-1,8-OCTANEDITHIOL 14970-87-7
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-09
Hebei Longbang Technology Co., Ltd
Product
3,6-DIOXA-1,8-OCTANEDITHIO 14970-87-7
Price
US $6.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20TONS
Release date
2024-04-26
Hebei Jingbo New Material Technology Co., Ltd
Product
3,6-DIOXA-1,8-OCTANEDITHIOL 14970-87-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000
Release date
2023-12-25

14970-87-7, 3,6-DIOXA-1,8-OCTANEDITHIOLRelated Search:

1,3,5,7,9,11,14-HEPTA-ISOOCTYLTRICYCLO(7.) HEPTASILOXANE-ENDO-3,7,14-TRIOL, 95% 1,3-Dimercaptopropane Ethanethiol 1,8-Octanedithiol Glycol dimercaptoacetate 3,6-DIOXA-1,8-OCTANEDITHIOL 8 9-DICYANO-1 4-DIOXA-7 10-DITHIACYCLO-& 3,6-Dioxaoctane-1,8-diyl Bismethanethiosulfonate 1,4,10,13-tetraoxa-7,16-dithiacyclooctadecane GLYCERYL THIOGLYCOLATE

  • Triglycoldimercaptan
  • ETHYLENE GLYCOL BIS(2-MERCAPTOETHYL) ETHER
  • 1,8-DIMERCAPTO-3,6-DIOXAOCTANE
  • 1,2-BIS(2-MERCAPTOETHOXY)ETHANE
  • 3,6-DIOXA-1,8-OCTANEDITHIOL
  • Triethyleneglycol dimrcaptan
  • Ethanethiol, 2,2-1,2-ethanediylbis(oxy)bis-
  • 2,2′-[1,2-Ethandiylbis(oxy)]bis(ethanthiol)
  • 2,2'-[1,2-ethanediylbis(oxy)]bis-Ethanethiol Triglycol dimercaptan 2,2'-[1,2-ethanediylbis(oxy)]bis-ethanethio 2,2'-(ethylenedioxy)diethanethiol
  • Triethyleneglycol dimercaptan
  • 1,2-Bis(2-mercaptoethoxy)ethane, 3,6-Dioxa-1,8-octane-dithiol
  • 2,2'-(Ethylenebisoxy)bisethanethiol
  • 3,6-dioxa-1,8-octandithiol
  • 2,2'-Ethylenebis(oxy)bis(ethanethiol)
  • 3,6-Dioxa-1,8-octanebisthiol
  • 1,2-Bis(2-mercaptoethoxy)ethane 1,8-Dimercapto-3,6-dioxaoctane Ethylene Glycol Bis(2-mercaptoethyl) Ether
  • 3,6-Dioxa-1,8-OCLanedithiol
  • 2,2’-(ethylenedioxy)diethanethiol
  • 2,2’-[1,2-ethanediylbis(oxy)]bis-ethanethio
  • 2,2’-[1,2-ethanediylbis(oxy)]bis-Ethanethiol
  • 2,2'-(ethane-1,2-diylbis(oxy))diethanethiol
  • 2,2'-(Ethylenedioxy)diethanethiol 95%
  • 3,6-Dioxa-1,8-octanedithiol &gt
  • 2-[2-(2-sulfanylethoxy)ethoxy]ethanethiol
  • 2,2′-(Ethylenedioxy)diethanethiol (DMDO)
  • SH-PEG2-SH
  • 3,6-Dioxa-1,8-Octanedithiol CAS NO.14970-87-7
  • 3,6-dioxy-1,8-octyldithiol
  • 3,6-DIOXA-1,8-OCTANEDITHIO
  • 14970-87-7
  • HSCH2CH2OCH2CH2OCH2CH2SH
  • C2H14O2S2
  • peg