3,6-DIOXA-1,8-OCTANEDITHIOL
- Product Name
- 3,6-DIOXA-1,8-OCTANEDITHIOL
- CAS No.
- 14970-87-7
- Chemical Name
- 3,6-DIOXA-1,8-OCTANEDITHIOL
- Synonyms
- 1,8-DIMERCAPTO-3,6-DIOXAOCTANE;2,2’-(ethylenedioxy)diethanethiol;SH-PEG2-SH;Triglycoldimercaptan;3,6-dioxa-1,8-octandithiol;3,6-dioxy-1,8-octyldithiol;3,6-DIOXA-1,8-OCTANEDITHIO;3,6-DIOXA-1,8-OCTANEDITHIOL;3,6-Dioxa-1,8-OCLanedithiol;Triethyleneglycol dimrcaptan
- CBNumber
- CB5379455
- Molecular Formula
- C6H14O2S2
- Formula Weight
- 182.3
- MOL File
- 14970-87-7.mol
3,6-DIOXA-1,8-OCTANEDITHIOL Property
- Boiling point:
- 225 °C(lit.)
- Density
- 1.12 g/mL at 25 °C(lit.)
- vapor pressure
- 0.39Pa at 20℃
- refractive index
- n20/D 1.509(lit.)
- Flash point:
- 132 °C
- solubility
- Slightly soluble in water
- form
- clear liquid
- pka
- 9.34±0.10(Predicted)
- color
- Colorless to Light yellow to Light orange
- Water Solubility
- 11.4g/L at 19.8℃
- BRN
- 1901671
- InChI
- InChI=1S/C6H14O2S2/c9-5-3-7-1-2-8-4-6-10/h9-10H,1-6H2
- InChIKey
- HCZMHWVFVZAHCR-UHFFFAOYSA-N
- SMILES
- C(OCCS)COCCS
- LogP
- 1.6 at 55℃
- CAS DataBase Reference
- 14970-87-7(CAS DataBase Reference)
- EPA Substance Registry System
- Ethanethiol, 2,2'-[1,2-ethanediylbis(oxy)]bis- (14970-87-7)
Safety
- Hazard Codes
- T,N,Xn
- Risk Statements
- 22-23-36/37/38-51/53-20/22
- Safety Statements
- 26-45-61
- RIDADR
- UN 2810 6.1/PG 3
- WGK Germany
- 2
- HS Code
- 29309090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H332Harmful if inhaled
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 465178
- Product name
- 2,2′-(Ethylenedioxy)diethanethiol
- Purity
- 95%
- Packaging
- 100ml
- Price
- $46.4
- Updated
- 2024/03/01
- Product number
- 465178
- Product name
- 2,2′-(Ethylenedioxy)diethanethiol
- Purity
- 95%
- Packaging
- 500ml
- Price
- $137.6
- Updated
- 2024/03/01
- Product number
- D2649
- Product name
- 3,6-Dioxa-1,8-octanedithiol
- Purity
- >97.0%(GC)(T)
- Packaging
- 25g
- Price
- $23
- Updated
- 2024/03/01
- Product number
- D2649
- Product name
- 3,6-Dioxa-1,8-octanedithiol
- Purity
- >97.0%(GC)(T)
- Packaging
- 100g
- Price
- $66
- Updated
- 2024/03/01
- Product number
- D2649
- Product name
- 3,6-Dioxa-1,8-octanedithiol
- Purity
- >97.0%(GC)(T)
- Packaging
- 500g
- Price
- $198
- Updated
- 2024/03/01
3,6-DIOXA-1,8-OCTANEDITHIOL Chemical Properties,Usage,Production
Uses
3,6-dioxa-1,8-octanedithiol (DODT) was used for cleaving peptides in the study to develop synthetic peptide serology to treat chronic chagas disease. DODT may be used to develop non-malodorous scavenger in Fmoc-based peptide synthesis.
Definition
3,6-dioxa-1,8-octanedithiol is a dithiol monomer. This compound could be chosen as a model compound for the active sites of thioredoxins to study its reactions with cis-[Pt(NH3)2Cl4] and trans-[PtCl2(CN)4]2– (cisplatin prodrug and a model complex). The pKa values for the dithiol were characterized to be 8.7 ± 0.2 and 9.6 ± 0.2 at 25.0 °C and an ionic strength of 1.0 M. Triethylamine (TEA) and dilute H2O2 could catalyze the new Radical Ring-opening Redox Polymerization (R3P) of 3,6-dioxa-1,8-octanedithiol[1-2].
Synthesis Reference(s)
The Journal of Organic Chemistry, 33, p. 1275, 1968 DOI: 10.1021/jo01267a089
Triglycol dimercaptan
General Description
3,6-dioxa-1,8-octanedithiol is non volatile in nature.
References
[1] DONGYING MA. Formation of peptide disulfide bonds through a trans-dibromido-Pt(IV) complex oxidation reaction: Kinetic and mechanistic analyses[J]. Journal of Molecular Liquids, 2021. DOI:10.1016/j.molliq.2020.115195.
[2] ROSENTHAL-KIMEMILY Q PuskasJudit E. Green polymer chemistry: investigating the mechanism of radical ring-opening redox polymerization (R3P) of 3,6-dioxa-1,8-octanedithiol (DODT).[J]. Molecules, 2015. DOI:10.3390/molecules20046504.
3,6-DIOXA-1,8-OCTANEDITHIOL Preparation Products And Raw materials
Raw materials
Preparation Products
3,6-DIOXA-1,8-OCTANEDITHIOL Suppliers
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View Lastest Price from 3,6-DIOXA-1,8-OCTANEDITHIOL manufacturers
- Product
- 3,6-DIOXA-1,8-OCTANEDITHIOL 14970-87-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000
- Release date
- 2023-12-25
- Product
- 3,6-DIOXA-1,8-OCTANEDITHIOL 14970-87-7
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-09
- Product
- 2,2 -(Ethylenedioxy)diethanethiol 14970-87-7
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-21