ChemicalBook > CAS DataBase List > 1-BENZOYL-3-PHENYL-2-THIOUREA

1-BENZOYL-3-PHENYL-2-THIOUREA

Product Name
1-BENZOYL-3-PHENYL-2-THIOUREA
CAS No.
4921-82-8
Chemical Name
1-BENZOYL-3-PHENYL-2-THIOUREA
Synonyms
usafk-1473;phenylbenzoylthiourea;1-Benzoyl-3-phenylthiourea;N-Phenyl-N'-benzoylthiourea;N-Benzoyl-N'-phenylthiourea;1-Benzoyl-3-phenyl(thiourea);1-BENZOYL-3-PHENYL-2-THIOUREA;1-benzoyl-3-phenyl-2-thio-ure;n-phenylthiocarbamoyl-benzamid;N-(Phenylthiocarbamoyl)benzamide
CBNumber
CB5380011
Molecular Formula
C14H12N2OS
Formula Weight
256.32
MOL File
4921-82-8.mol
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1-BENZOYL-3-PHENYL-2-THIOUREA Property

Melting point:
159 °C
Density 
1.290±0.06 g/cm3(Predicted)
storage temp. 
-20°
solubility 
Soluble in DMSO (greater than 50 mg/ml) or in Ethanol (up to 8 mg/ml).
form 
solid
pka
9.49±0.70(Predicted)
color 
Off-white
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
CAS DataBase Reference
4921-82-8(CAS DataBase Reference)
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Safety

HazardClass 
IRRITANT
HS Code 
2930909899
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S505528
Product name
1-BENZOYL-3-PHENYL-2-THIOUREA
Purity
Aldrich
Packaging
1g
Price
$179
Updated
2024/03/01
Matrix Scientific
Product number
056642
Product name
1-Benzoyl-3-phenyl-2-thiourea
Purity
98%
Packaging
25g
Price
$330
Updated
2021/12/16
Oakwood
Product number
018201
Product name
1-Benzoyl-3-phenyl-2-thiourea
Purity
98%
Packaging
25g
Price
$335
Updated
2021/12/16
Matrix Scientific
Product number
056642
Product name
1-Benzoyl-3-phenyl-2-thiourea
Purity
98%
Packaging
1mg
Price
$27
Updated
2021/12/16
Oakwood
Product number
018201
Product name
1-Benzoyl-3-phenyl-2-thiourea
Purity
98%
Packaging
1g
Price
$28
Updated
2021/12/16
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1-BENZOYL-3-PHENYL-2-THIOUREA Chemical Properties,Usage,Production

Description

TM-2-51 (4921-82-8) is a highly potent and isozyme selective activator of recombinant HDAC8. Increases the activity of HDAC8 by a factor of 12 at 10 μM. No activation of other HDACs is observed. TM-2-51 rescues the activity of catalytically compromised HDAC8 mutants?in vitro.2

References

1) Singh?et al. (2011), Histone deacetylase activators: N-acetylthioureas as highly potent and isozyme selective activators for human histone deacetylase-8 on a fluorescent substrate; Bioorg. Med. Chem. Lett.,?21?5920 2) Decross?et al. (2014), Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders; ACS Chem. Biol.,?9?2157 3) Singh?et al. (2015),?Mechanism of N-acylthiourea Mediated Activation of Human Histone Deacetylase 8 (HDAC8) at Molecular and Cellular Levels; J. Biol. Chem.,?290?6607

1-BENZOYL-3-PHENYL-2-THIOUREA Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BENZOYL-3-PHENYL-2-THIOUREA Suppliers

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Wuhan Chemwish Technology Co., Ltd
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86-027-67849912
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86-027-87531808
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sales@chemwish.com
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
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+86-21-54098501
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+86-21-54096319
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sales@sinch.com.cn
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Beijing FYF Chemicals Co., Ltd
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Sigma-Aldrich
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orderCN@merckgroup.com
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Wuhan Chemwish Technology Co., Ltd
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Amadis Chemical Company Limited
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Shenzhen Regent Biochemical Technology Co., Ltd.
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 13028896684
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Career Henan Chemica Co
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+86-0371-86658258 15093356674;
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0371-86658258
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laboratory@coreychem.com
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4921-82-8, 1-BENZOYL-3-PHENYL-2-THIOUREARelated Search:


  • N-[anilino(sulfanylidene)methyl]benzamide
  • 1-benzoyl-3-phenyl-2-thio-ure
  • n-phenylthiocarbamoyl-benzamid
  • phenylbenzoylthiourea
  • usafk-1473
  • 1-Benzoyl-3-phenyl(thiourea)
  • 1-Benzoyl-3-phenylthiourea
  • N-(Phenylthiocarbamoyl)benzamide
  • N-Benzoyl-N'-phenylthiourea
  • N-Phenyl-N'-benzoylthiourea
  • 1-BENZOYL-3-PHENYL-2-THIOUREA
  • N-[(PHENYLAMINO)THIOXOMETHYL]-BENZAMIDE
  • Benzamide, N-[(phenylamino)thioxomethyl]-
  • N-(Phenylcarbamothioyl)benzamide
  • 4921-82-8
  • C14H12N2OS