1-BENZOYL-3-PHENYL-2-THIOUREA
- Product Name
- 1-BENZOYL-3-PHENYL-2-THIOUREA
- CAS No.
- 4921-82-8
- Chemical Name
- 1-BENZOYL-3-PHENYL-2-THIOUREA
- Synonyms
- usafk-1473;phenylbenzoylthiourea;1-Benzoyl-3-phenylthiourea;N-Phenyl-N'-benzoylthiourea;N-Benzoyl-N'-phenylthiourea;1-Benzoyl-3-phenyl(thiourea);1-BENZOYL-3-PHENYL-2-THIOUREA;1-benzoyl-3-phenyl-2-thio-ure;n-phenylthiocarbamoyl-benzamid;N-(Phenylthiocarbamoyl)benzamide
- CBNumber
- CB5380011
- Molecular Formula
- C14H12N2OS
- Formula Weight
- 256.32
- MOL File
- 4921-82-8.mol
1-BENZOYL-3-PHENYL-2-THIOUREA Property
- Melting point:
- 159 °C
- Density
- 1.290±0.06 g/cm3(Predicted)
- storage temp.
- -20°
- solubility
- Soluble in DMSO (greater than 50 mg/ml) or in Ethanol (up to 8 mg/ml).
- form
- solid
- pka
- 9.49±0.70(Predicted)
- color
- Off-white
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
- CAS DataBase Reference
- 4921-82-8(CAS DataBase Reference)
Safety
- HazardClass
- IRRITANT
- HS Code
- 2930909899
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- S505528
- Product name
- 1-BENZOYL-3-PHENYL-2-THIOUREA
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $179
- Updated
- 2024/03/01
- Product number
- 056642
- Product name
- 1-Benzoyl-3-phenyl-2-thiourea
- Purity
- 98%
- Packaging
- 25g
- Price
- $330
- Updated
- 2021/12/16
- Product number
- 018201
- Product name
- 1-Benzoyl-3-phenyl-2-thiourea
- Purity
- 98%
- Packaging
- 25g
- Price
- $335
- Updated
- 2021/12/16
- Product number
- 056642
- Product name
- 1-Benzoyl-3-phenyl-2-thiourea
- Purity
- 98%
- Packaging
- 1mg
- Price
- $27
- Updated
- 2021/12/16
- Product number
- 018201
- Product name
- 1-Benzoyl-3-phenyl-2-thiourea
- Purity
- 98%
- Packaging
- 1g
- Price
- $28
- Updated
- 2021/12/16
1-BENZOYL-3-PHENYL-2-THIOUREA Chemical Properties,Usage,Production
Description
TM-2-51 (4921-82-8) is a highly potent and isozyme selective activator of recombinant HDAC8. Increases the activity of HDAC8 by a factor of 12 at 10 μM. No activation of other HDACs is observed. TM-2-51 rescues the activity of catalytically compromised HDAC8 mutants?in vitro.2
References
1) Singh?et al. (2011), Histone deacetylase activators: N-acetylthioureas as highly potent and isozyme selective activators for human histone deacetylase-8 on a fluorescent substrate; Bioorg. Med. Chem. Lett.,?21?5920 2) Decross?et al. (2014), Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders; ACS Chem. Biol.,?9?2157 3) Singh?et al. (2015),?Mechanism of N-acylthiourea Mediated Activation of Human Histone Deacetylase 8 (HDAC8) at Molecular and Cellular Levels; J. Biol. Chem.,?290?6607
1-BENZOYL-3-PHENYL-2-THIOUREA Preparation Products And Raw materials
Raw materials
Preparation Products
1-BENZOYL-3-PHENYL-2-THIOUREA Suppliers
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View Lastest Price from 1-BENZOYL-3-PHENYL-2-THIOUREA manufacturers
- Product
- 1-BENZOYL-3-PHENYL-2-THIOUREA 4921-82-8
- Price
- US $1.00-2.10/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20000KG
- Release date
- 2024-08-09