1-BENZOYL-3-PHENYL-2-THIOUREA

Product Name: 1-BENZOYL-3-PHENYL-2-THIOUREA
CAS No.: 4921-82-8
Chemical Name: 1-BENZOYL-3-PHENYL-2-THIOUREA
Synonyms: usafk-1473;phenylbenzoylthiourea;1-Benzoyl-3-phenylthiourea;N-Phenyl-N'-benzoylthiourea;N-Benzoyl-N'-phenylthiourea;1-Benzoyl-3-phenyl(thiourea);1-BENZOYL-3-PHENYL-2-THIOUREA;1-benzoyl-3-phenyl-2-thio-ure;n-phenylthiocarbamoyl-benzamid;N-(Phenylthiocarbamoyl)benzamide
CBNumber: CB5380011
Molecular Formula: C14H12N2OS
Formula Weight: 256.32
MOL File: 4921-82-8.mol

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1-BENZOYL-3-PHENYL-2-THIOUREA Property

Melting point:: 159 °C
Density: 1.290±0.06 g/cm3(Predicted)
storage temp.: -20°
solubility: Soluble in DMSO (greater than 50 mg/ml) or in Ethanol (up to 8 mg/ml).
form: solid
pka: 9.49±0.70(Predicted)
color: Off-white
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
CAS DataBase Reference: 4921-82-8(CAS DataBase Reference)

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Safety

HazardClass: IRRITANT
HS Code: 2930909899

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S505528
Product name: 1-BENZOYL-3-PHENYL-2-THIOUREA
Purity: Aldrich
Packaging: 1g
Price: $179
Updated: 2024/03/01

Matrix Scientific

Product number: 056642
Product name: 1-Benzoyl-3-phenyl-2-thiourea
Purity: 98%
Packaging: 25g
Price: $330
Updated: 2021/12/16

Oakwood

Product number: 018201
Product name: 1-Benzoyl-3-phenyl-2-thiourea
Purity: 98%
Packaging: 25g
Price: $335
Updated: 2021/12/16

Matrix Scientific

Product number: 056642
Product name: 1-Benzoyl-3-phenyl-2-thiourea
Purity: 98%
Packaging: 1mg
Price: $27
Updated: 2021/12/16

Oakwood

Product number: 018201
Product name: 1-Benzoyl-3-phenyl-2-thiourea
Purity: 98%
Packaging: 1g
Price: $28
Updated: 2021/12/16

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1-BENZOYL-3-PHENYL-2-THIOUREA Chemical Properties,Usage,Production

Description

TM-2-51 (4921-82-8) is a highly potent and isozyme selective activator of recombinant HDAC8. Increases the activity of HDAC8 by a factor of 12 at 10 μM. No activation of other HDACs is observed. TM-2-51 rescues the activity of catalytically compromised HDAC8 mutants?in vitro.2

References

1) Singh?et al. (2011), Histone deacetylase activators: N-acetylthioureas as highly potent and isozyme selective activators for human histone deacetylase-8 on a fluorescent substrate; Bioorg. Med. Chem. Lett.,?21?5920 2) Decross?et al. (2014), Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders; ACS Chem. Biol.,?9?2157 3) Singh?et al. (2015),?Mechanism of N-acylthiourea Mediated Activation of Human Histone Deacetylase 8 (HDAC8) at Molecular and Cellular Levels; J. Biol. Chem.,?290?6607

1-BENZOYL-3-PHENYL-2-THIOUREA Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BENZOYL-3-PHENYL-2-THIOUREA Suppliers

China 27 France 1 Germany 2 United Kingdom 6 United States 12 Global 48

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View Lastest Price from 1-BENZOYL-3-PHENYL-2-THIOUREA manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 1-BENZOYL-3-PHENYL-2-THIOUREA 4921-82-8
Price: US $1.00-2.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20000KG
Release date: 2024-08-09

4921-82-8, 1-BENZOYL-3-PHENYL-2-THIOUREARelated Search:

N-BENZOYL-N'-(4-[(E)-2-PHENYLDIAZENYL]PHENYL)THIOUREA 1-BENZOYL-3-PHENYL-2-THIOUREA SALOR-INT L308269-1EA AURORA 3570 N-BENZOYL-N'-(4-NITROPHENYL)THIOUREA AURORA 48 5-(([(4-CHLOROANILINO)CARBOTHIOYL]AMINO)CARBONYL)-2,1,3-BENZOXADIAZOL-1-IUM-1-OLATE AURORA 2108 AURORA 7338 5-([(ANILINOCARBOTHIOYL)AMINO]CARBONYL)-2,1,3-BENZOXADIAZOL-1-IUM-1-OLATE 5-[(([3-(TRIFLUOROMETHYL)ANILINO]CARBOTHIOYL)AMINO)CARBONYL]-2,1,3-BENZOXADIAZOL-1-IUM-1-OLATE AURORA 1039 AURORA 1125 AURORA 7340 N-BENZOYL-N'-[3-(TRIFLUOROMETHYL)PHENYL]THIOUREA AURORA 466 AURORA 3820 AURORA 1098

N-[anilino(sulfanylidene)methyl]benzamide

1-benzoyl-3-phenyl-2-thio-ure

n-phenylthiocarbamoyl-benzamid

phenylbenzoylthiourea

usafk-1473

1-Benzoyl-3-phenyl(thiourea)

1-Benzoyl-3-phenylthiourea

N-(Phenylthiocarbamoyl)benzamide

N-Benzoyl-N'-phenylthiourea

N-Phenyl-N'-benzoylthiourea

1-BENZOYL-3-PHENYL-2-THIOUREA

N-[(PHENYLAMINO)THIOXOMETHYL]-BENZAMIDE

Benzamide, N-[(phenylamino)thioxomethyl]-

N-(Phenylcarbamothioyl)benzamide

4921-82-8

C14H12N2OS