6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE

Product Name: 6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE
CAS No.: 22190-35-8
Chemical Name: 6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE
Synonyms: TIMTEC-BB SBB013968;UKRORGSYN-BB BBV-052938;6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE;quinoline, 6-bromo-1,2,3,4-tetrahydro-;6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE，97% min;6-broMo-1,2,3,4-tetrahydroquinoline hydrocholide;6-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HCL 6-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE
CBNumber: CB5391516
Molecular Formula: C9H10BrN
Formula Weight: 212.09
MOL File: 22190-35-8.mol

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6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE Property

Boiling point:: 303.1±31.0 °C(Predicted)
Density: 1.428±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 4.26±0.20(Predicted)
form: low melting solid
color: Light yellow to brown
InChI: InChI=1S/C9H10BrN/c10-8-3-4-9-7(6-8)2-1-5-11-9/h3-4,6,11H,1-2,5H2
InChIKey: WEHMHBSITKCQBY-UHFFFAOYSA-N
SMILES: N1C2=C(C=C(Br)C=C2)CCC1

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Safety

HazardClass: IRRITANT
HS Code: 2933499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B415483
Product name: 6-Bromo-1,2,3,4-tetrahydroquinoline
Packaging: 50mg
Price: $60
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H31-9-03
Product name: 6-Bromo-1,2,3,4-tetrahydroquinoline
Purity: 95%
Packaging: 100mg
Price: $40
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB42083
Product name: 6-Bromo-1,2,3,4-tetrahydroquinoline
Packaging: 2g
Price: $216
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H31-9-03
Product name: 6-Bromo-1,2,3,4-tetrahydroquinoline
Purity: 95%
Packaging: 1g
Price: $255
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H31-9-03
Product name: 6-Bromo-1,2,3,4-tetrahydroquinoline
Purity: 95%
Packaging: 250mg
Price: $85
Updated: 2021/12/16

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6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE Chemical Properties,Usage,Production

Synthesis

635-46-1

22190-35-8

General steps: 1. Bromination reaction: To a stirred acetonitrile solution of 1,2,3,4-tetrahydroquinoline (20.0 g, 150 mmol, 1.0 eq.) was added N-bromosuccinimide (25.5 g, 143 mmol, 0.95 eq.) in 4 portions at 0°C, each 20 minutes apart. The reaction mixture was continued to be stirred for 3 h at 0 °C. 2. Reaction monitoring: the progress of the reaction was monitored by thin layer chromatography (TLC), the unfolding agent was 10% ethyl acetate-hexane and the product Rf value was 0.55. 3. Post-treatment: After completion of the reaction, the organic layer was diluted with the addition of ether and washed sequentially with saturated sodium bicarbonate solution, water and brine. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. 4. Purification: The crude product was purified by column chromatography on silica gel (100-200 mesh) with hexane solution of 5% ethyl acetate as eluent to give 6-bromo-1,2,3,4-tetrahydroquinoline (20.0 g, 64% yield) as a yellow oil. 5. Characterization of the product: Liquid chromatography-mass spectrometry (LCMS) analysis showed a purity of 92.25% (ES+): m/z 212.0 (M+H+); retention time (tr) = 2.06 min.

References

[1] Tetrahedron, 2005, vol. 61, # 16, p. 4035 - 4041
[2] Patent: WO2012/94462, 2012, A2. Location in patent: Page/Page column 60
[3] Patent: US2008/221160, 2008, A1. Location in patent: Page/Page column 11; 12
[4] Patent: EP2172453, 2010, A1. Location in patent: Page/Page column 11
[5] Patent: WO2013/166015, 2013, A1. Location in patent: Paragraph 0093 - 0095

6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE Suppliers

China 141 Finland 1 India 3 Russia 1 Ukraine 1 United Kingdom 3 United States 9 Global 159

A.J Chemicals

Tel: --
Fax: --
Email: sales@ajchem.in
Country: India
ProdList: 6100
Advantage: 58

SL Drugs and Pharmaceuticals Pvt. Ltd.

Tel: --
Fax: --
Email: enquiry@sldrugs.com
Country: India
ProdList: 2683
Advantage: 50

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View Lastest Price from 6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE manufacturers

Career Henan Chemical Co

Product: 6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE 22190-35-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-03

22190-35-8, 6-BROMO-1,2,3,4-TETRAHYDROQUINOLINERelated Search:

6-bromo-2,3,4,9-tetrahydro-1H-carbazole 6-bromo-1,2,3,4-tetrahydroisoquinoline 6-BROMO-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE 6-Bromo-2,3-Dihydroquinolin-4(1H)-One 6-BROMO-3,4-DIHYDRO-1H-QUINOLIN-2-ONE 6-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE-2-CARBOXYLIC ACID METHYL ESTER 6-BROMO-3,4-DIHYDRO-4,4-DIMETHYLQUINOLIN-2(1H)-ONE 6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE 9-BROMO-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE 1-acetyl-6-bromo-1,2,3,4-tetrahydroquinoline 6-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE-3-CARBOXYLIC ACID AURORA KA-4644 ASISCHEM N57875 AURORA KA-4057 AURORA KA-4056 4(1H)-Quinolinone, 6-bromo-2,3-dihydro-1-(1-oxopropyl)-, 4-oxime ASISCHEM N57876 1(2H)-Quinolinecarboxamide, 6-bromo-3,4-dihydro-4-(hydroxyimino)-N-met hyl-

6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE

TIMTEC-BB SBB013968

UKRORGSYN-BB BBV-052938

quinoline, 6-bromo-1,2,3,4-tetrahydro-

6-broMo-1,2,3,4-tetrahydroquinoline hydrocholide

6-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HCL 6-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE

6-BROMO-1,2,3,4-TETRAHYDROQUINOLINE，97% min

22190-35-8