H-GLY-NHME HCL
- Product Name
- H-GLY-NHME HCL
- CAS No.
- 49755-94-4
- Chemical Name
- H-GLY-NHME HCL
- Synonyms
- H-Gly-NHMe;Gly-NHMe·HCl;H-GLY-NHME HCL;GLYCINE-NHME HCL;H-Gly-nhme hydrochloride;H-GLY-NHME HCL USP/EP/BP;2-AMINO-N-METHYLACETAMIDE HYDR;2-AMino-N-Methyl-acetaMide HCl;N-Methylglycinamide hydrochloride;GLYCINE METHYLAMIDE HYDROCHLORIDE
- CBNumber
- CB5393000
- Molecular Formula
- C3H9ClN2O
- Formula Weight
- 124.57
- MOL File
- 49755-94-4.mol
H-GLY-NHME HCL Property
- Melting point:
- 154-156℃
- storage temp.
- Inert atmosphere,2-8°C
- form
- Powder
- color
- Off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 238839
- Product name
- Glycine-N-methylamide hydrochloride
- Packaging
- 250mg
- Price
- $179
- Updated
- 2021/12/16
- Product number
- A613080
- Product name
- 2-Amino-N-methylacetamideHydrochloride
- Packaging
- 5g
- Price
- $240
- Updated
- 2021/12/16
- Product number
- 278512
- Product name
- Glycine-N-methylamide hydrochloride
- Packaging
- 500mg
- Price
- $333
- Updated
- 2021/12/16
- Product number
- 052706
- Product name
- 2-Amino-N-methylacetamide hydrochloride
- Packaging
- 500mg
- Price
- $10
- Updated
- 2021/12/16
- Product number
- 052706
- Product name
- 2-Amino-N-methylacetamide hydrochloride
- Packaging
- 2.500g
- Price
- $20
- Updated
- 2021/12/16
H-GLY-NHME HCL Chemical Properties,Usage,Production
Uses
2-Amino-N-methylacetamide is an intermediate used to prepare macrocyclic hydroxamic acids that inhibit tumor necrosis factor α. It is also used to synthesize 2-[(arylalkyl)amino]alkanamide derivatives with anticonvulsant activities.
Synthesis
88815-85-4
49755-94-4
Tert-butyl N-[(methylcarbamoyl)methyl]carbamate (300 mg, 1.59 mmol, 1.00 eq.) was dissolved in dichloromethane (5 mL), hydrochloric acid (1.2 mL) was added, and the reaction was stirred for 4 hours at room temperature. After completion of the reaction, the mixture was concentrated under vacuum to give 2-amino-N-methylacetamide hydrochloride (185 mg), the product was a colorless oil. Mass spectrum (MS): m/z 89 (M + H)+. Nuclear magnetic resonance hydrogen spectrum (1H NMR, 300 MHz, CDCl3): δ 8.45 (br s, 1H), 8.19 (s, 3H), 3.50 (d, 2H), 2.65 (d, 3H).
References
[1] Journal of the American Chemical Society, 1992, vol. 114, # 12, p. 4834 - 4843
[2] Journal de Chimie Physique et de Physico-Chimie Biologique, 1988, vol. 85, # 5, p. 583 - 588
[3] Patent: WO2013/106535, 2013, A1. Location in patent: Paragraph 00571
H-GLY-NHME HCL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from H-GLY-NHME HCL manufacturers
- Product
- H-GLY-NHME HCL 49755-94-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09