4-(1-Naphthalenyl)-2-thiazolamine Property

Melting point:

155-158°C

Boiling point:

428.4±14.0 °C(Predicted)

Density 

1.301±0.06 g/cm3(Predicted)

pka

4.58±0.10(Predicted)

form 

powder to crystal

color 

Light yellow to Yellow to Orange

λmax

223nm(Buffer)(lit.)

BRN 

164858

CAS DataBase Reference

56503-96-9(CAS DataBase Reference)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

RTECS 

XJ1990000

HS Code 

2934.10.2000

HazardClass 

IRRITANT

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

4-(1-Naphthalenyl)-2-thiazolamine Chemical Properties,Usage,Production

Uses

2-Amino-4-(1-naphthyl)thiazole is a reagent used in the synthesis of 2-substituted ethenesulfonic acid ester derivatives as PTP1B inhibitors. Also used as a reagent in the preparation of pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors for the treatment of inflammation and various cancers.