ChemicalBook > CAS DataBase List > SIB 1757

SIB 1757

Product Name
SIB 1757
CAS No.
31993-01-8
Chemical Name
SIB 1757
Synonyms
SIB 1758;SIB 1757;6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL;6-Methyl-2-(phenyldiazenyl)pyridin-3-ol;6-methyl-2-[(E)-phenyldiazenyl]pyridin-3;(E)-6-Methyl-2-(phenyldiazenyl)pyridin-3-ol;6-Methyl-2-[(E)-phenyldiazenyl]pyridin-3-ol;SIB-1757 6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL;3-Pyridinol, 6-methyl-2-(2-phenyldiazenyl)-;SIB-1757,mGluR,SIB1757,Metabotropic glutamate receptors,inhibit,Inhibitor,SIB 1757
CBNumber
CB5404317
Molecular Formula
C12H11N3O
Formula Weight
213.24
MOL File
31993-01-8.mol
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SIB 1757 Property

storage temp. 
Store at RT
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
crystalline
color 
red
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S9186
Product name
SIB 1757
Purity
≥99% (HPLC), crystalline
Packaging
10MG
Price
$130
Updated
2024/03/01
Sigma-Aldrich
Product number
S9186
Product name
SIB 1757
Purity
≥99% (HPLC), crystalline
Packaging
50MG
Price
$511
Updated
2022/05/15
TRC
Product number
S411005
Product name
SIB1757
Packaging
25mg
Price
$140
Updated
2021/12/16
Usbiological
Product number
256663
Product name
SIB 1757
Packaging
10mg
Price
$389
Updated
2021/12/16
ApexBio Technology
Product number
B6636
Product name
SIB1757
Packaging
50mg
Price
$629
Updated
2021/12/16
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SIB 1757 Chemical Properties,Usage,Production

Uses

SIB 1757 is an antagonist for mGluR-5.

Definition

ChEBI: 6-methyl-2-(phenylhydrazinylidene)-3-pyridinone is a member of phenylhydrazines.

Biological Activity

A highly selective antagonist for the mGlu 5 metabotropic glutamate receptor subtype; displays an IC 50 value of 0.4 μ M at hmGlu 5 compared with > 30 μ M at hmGlu 1b , hmGlu 2 , hmGlu 4 , hmGlu 6 , hmGlu 7 and hmGlu 8 .

SIB 1757 Preparation Products And Raw materials

Raw materials

Preparation Products

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SIB 1757 Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91

31993-01-8, SIB 1757Related Search:


  • SIB 1757
  • SIB-1757 6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL
  • 6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL
  • 6-Methyl-2-[(E)-phenyldiazenyl]pyridin-3-ol
  • (E)-6-Methyl-2-(phenyldiazenyl)pyridin-3-ol
  • 6-methyl-2-[(E)-phenyldiazenyl]pyridin-3
  • 3-Pyridinol, 6-methyl-2-(2-phenyldiazenyl)-
  • SIB-1757,mGluR,SIB1757,Metabotropic glutamate receptors,inhibit,Inhibitor,SIB 1757
  • SIB 1758
  • 6-Methyl-2-(phenyldiazenyl)pyridin-3-ol
  • 31993-01-8
  • C12H11N3O
  • Glutamate receptor