4-HYDROXYPHTHALIC ANHYDRIDE

Product Name: 4-HYDROXYPHTHALIC ANHYDRIDE
CAS No.: 27550-59-0
Chemical Name: 4-HYDROXYPHTHALIC ANHYDRIDE
Synonyms: 5-hydroxyisobenzofuran-1,3-dione;4-Hydroxy-phthalicanhydrid;Hydroxyisobenzofuran4-HYDROXYPHTHALIC ANHYDRIDE;5-hydroxy-2-benzofuran-1,3-dione;1,3-Isobenzofurandione,5-hydroxy-;5-Hydroxy-1,3-isobenzofurandione, 98+%;5-hydroxy-1,3-dihydro-2-benzofuran-1,3-dione
CBNumber: CB5411627
Molecular Formula: C8H4O4
Formula Weight: 164.12
MOL File: 27550-59-0.mol

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4-HYDROXYPHTHALIC ANHYDRIDE Property

Melting point:: 171-173 °C(Solv: acetic acid (64-19-7))
Boiling point:: 407.8±28.0 °C(Predicted)
Density: 1.624±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 6.52±0.20(Predicted)
Appearance: Off-white to light brown Solid
InChI: InChI=1S/C8H4O4/c9-4-1-2-5-6(3-4)8(11)12-7(5)10/h1-3,9H
InChIKey: PXHIYFMTRHEUHZ-UHFFFAOYSA-N
SMILES: C1(=O)C2=C(C=C(O)C=C2)C(=O)O1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC

Product number: H950550
Product name: 5-Hydroxyisobenzofuran-1,3-dione
Packaging: 100mg
Price: $155
Updated: 2021/12/16

ChemScene

Product number: CS-W022391
Product name: 5-Hydroxyisobenzofuran-1,3-dione
Packaging: 100mg
Price: $46
Updated: 2021/12/16

ChemScene

Product number: CS-W022391
Product name: 5-Hydroxyisobenzofuran-1,3-dione
Packaging: 250mg
Price: $60
Updated: 2021/12/16

ChemScene

Product number: CS-W022391
Product name: 5-Hydroxyisobenzofuran-1,3-dione
Packaging: 1g
Price: $147
Updated: 2021/12/16

ChemScene

Product number: CS-W022391
Product name: 5-Hydroxyisobenzofuran-1,3-dione
Packaging: 5g
Price: $440
Updated: 2021/12/16

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4-HYDROXYPHTHALIC ANHYDRIDE Chemical Properties,Usage,Production

Uses

4-Hydroxyphthalic anhydride is a derivative of 3-hydroxyphthalic anhydride and can be used to modify proteins for in vitro biologics studies.

Synthesis

610-35-5

27550-59-0

The sublimation reaction was carried out at 220 °C and under vacuum conditions (~10 mbar) using 4-hydroxyphthalic acid (1 g, 5.49 mmol) as the raw material. Upon completion of the reaction, the resulting white solid 5-hydroxyisobenzofuran-1,3-dione (675 mg, 4.11 mmol, 74.9% yield, MS/ESI+ 164.9 [MH]+) was collected. The product is to be stored under vacuum and used directly in subsequent reaction steps.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 20, p. 4427 - 4431
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 1, p. 342 - 353
[3] Patent: CN104910113, 2017, B. Location in patent: Page/Page column 0041; 0044-0046
[4] European Journal of Medicinal Chemistry, 1987, vol. 22, p. 229 - 238
[5] Patent: US2013/102576, 2013, A1. Location in patent: Paragraph 0607

4-HYDROXYPHTHALIC ANHYDRIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-HYDROXYPHTHALIC ANHYDRIDE Suppliers

China 91 Germany 2 India 1 United Kingdom 1 United States 6 Global 101

Shanghai Boyners Pharm-Tech Co., Ltd.

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View Lastest Price from 4-HYDROXYPHTHALIC ANHYDRIDE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 4-HYDROXYPHTHALIC ANHYDRIDE 27550-59-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-29

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-HYDROXYPHTHALIC ANHYDRIDE 27550-59-0
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2025-03-11

Career Henan Chemical Co

Product: 4-HYDROXYPHTHALIC ANHYDRIDE 27550-59-0
Price: US $8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100MT
Release date: 2018-12-15

27550-59-0, 4-HYDROXYPHTHALIC ANHYDRIDERelated Search:

3-HYDROXYPHTHALIC ANHYDRIDE,3-HYDROXYPHTHALIC ANHYDRIDE 97+% HQDA AKOS 220-69 AKOS 243-36 5-Methoxy-isobenzofuran-1,3-dione AKOS 220-67 AKOS 200-04 AKOS 227-92 4,4'-(3,4-DICARBOXYPHENOXY)DIPHENYLSULFIDE DIANHYDRIDE AKOS 215-94 4,4'-(4,4'-ISOPROPYLIDENEDIPHENOXY)BIS(PHTHALIC ANHYDRIDE) 4-HYDROXYPHTHALIC ANHYDRIDE AKOS 212-66 4,4'-Oxydiphthalic anhydride

4-HYDROXYPHTHALIC ANHYDRIDE

5-hydroxy-2-benzofuran-1,3-dione

5-hydroxyisobenzofuran-1,3-dione

5-hydroxy-1,3-dihydro-2-benzofuran-1,3-dione

4-Hydroxy-phthalicanhydrid

1,3-Isobenzofurandione,5-hydroxy-

5-Hydroxy-1,3-isobenzofurandione, 98+%

Hydroxyisobenzofuran&#8203

27550-59-0

C8H4O4