ChemicalBook > CAS DataBase List > 4-HYDROXYPHTHALIC ANHYDRIDE
4-HYDROXYPHTHALIC ANHYDRIDE
- Product Name
- 4-HYDROXYPHTHALIC ANHYDRIDE
- CAS No.
- 27550-59-0
- Chemical Name
- 4-HYDROXYPHTHALIC ANHYDRIDE
- Synonyms
- 5-hydroxyisobenzofuran-1,3-dione;4-Hydroxy-phthalicanhydrid;Hydroxyisobenzofuran4-HYDROXYPHTHALIC ANHYDRIDE;5-hydroxy-2-benzofuran-1,3-dione;1,3-Isobenzofurandione,5-hydroxy-;5-Hydroxy-1,3-isobenzofurandione, 98+%;5-hydroxy-1,3-dihydro-2-benzofuran-1,3-dione
- CBNumber
- CB5411627
- Molecular Formula
- C8H4O4
- Formula Weight
- 164.12
- MOL File
- 27550-59-0.mol
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4-HYDROXYPHTHALIC ANHYDRIDE Property
- Melting point:
- 171-173 °C(Solv: acetic acid (64-19-7))
- Boiling point:
- 407.8±28.0 °C(Predicted)
- Density
- 1.624±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 6.52±0.20(Predicted)
- Appearance
- Off-white to light brown Solid
- InChI
- InChI=1S/C8H4O4/c9-4-1-2-5-6(3-4)8(11)12-7(5)10/h1-3,9H
- InChIKey
- PXHIYFMTRHEUHZ-UHFFFAOYSA-N
- SMILES
- C1(=O)C2=C(C=C(O)C=C2)C(=O)O1
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
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N-Bromosuccinimide Price
TRC
- Product number
- H950550
- Product name
- 5-Hydroxyisobenzofuran-1,3-dione
- Packaging
- 100mg
- Price
- $155
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-W022391
- Product name
- 5-Hydroxyisobenzofuran-1,3-dione
- Packaging
- 100mg
- Price
- $46
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-W022391
- Product name
- 5-Hydroxyisobenzofuran-1,3-dione
- Packaging
- 250mg
- Price
- $60
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-W022391
- Product name
- 5-Hydroxyisobenzofuran-1,3-dione
- Packaging
- 5g
- Price
- $440
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM1040106
- Product name
- 4-HYDROXYPHTHALIC ANHYDRIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.79
- Updated
- 2021/12/16
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4-HYDROXYPHTHALIC ANHYDRIDE Chemical Properties,Usage,Production
Uses
4-Hydroxyphthalic anhydride is a derivative of 3-hydroxyphthalic anhydride and can be used to modify proteins for in vitro biologics studies.
Synthesis
610-35-5
27550-59-0
The sublimation reaction was carried out at 220 °C and under vacuum conditions (~10 mbar) using 4-hydroxyphthalic acid (1 g, 5.49 mmol) as the raw material. Upon completion of the reaction, the resulting white solid 5-hydroxyisobenzofuran-1,3-dione (675 mg, 4.11 mmol, 74.9% yield, MS/ESI+ 164.9 [MH]+) was collected. The product is to be stored under vacuum and used directly in subsequent reaction steps.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 20, p. 4427 - 4431
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 1, p. 342 - 353
[3] Patent: CN104910113, 2017, B. Location in patent: Page/Page column 0041; 0044-0046
[4] European Journal of Medicinal Chemistry, 1987, vol. 22, p. 229 - 238
[5] Patent: US2013/102576, 2013, A1. Location in patent: Paragraph 0607
4-HYDROXYPHTHALIC ANHYDRIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-HYDROXYPHTHALIC ANHYDRIDE manufacturers
Henan Aochuang Chemical Co.,Ltd.
- Product
- 4-HYDROXYPHTHALIC ANHYDRIDE 27550-59-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-29
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- 4-HYDROXYPHTHALIC ANHYDRIDE 27550-59-0
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2025-03-11
Career Henan Chemical Co
- Product
- 4-HYDROXYPHTHALIC ANHYDRIDE 27550-59-0
- Price
- US $8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100MT
- Release date
- 2018-12-15
27550-59-0, 4-HYDROXYPHTHALIC ANHYDRIDERelated Search:
3-HYDROXYPHTHALIC ANHYDRIDE,3-HYDROXYPHTHALIC ANHYDRIDE 97+%
HQDA
AKOS 220-69
AKOS 243-36
5-Methoxy-isobenzofuran-1,3-dione
AKOS 220-67
AKOS 200-04
AKOS 227-92
4,4'-(3,4-DICARBOXYPHENOXY)DIPHENYLSULFIDE DIANHYDRIDE
AKOS 215-94
4,4'-(4,4'-ISOPROPYLIDENEDIPHENOXY)BIS(PHTHALIC ANHYDRIDE)
4-HYDROXYPHTHALIC ANHYDRIDE
AKOS 212-66
4,4'-Oxydiphthalic anhydride