SPINOSAD

Product Name: SPINOSAD
CAS No.: 168316-95-8
Chemical Name: SPINOSAD
Synonyms: SPINOS;Spinosads;oxysaccharin;Spinosad [iso];Spinosad (CRM);Spinosad Standard;Tracer naturalyte;SPINOSAD USP/EP/BP;C16972830 Spinosad;Spinosad in Acetone
CBNumber: CB5416798
Molecular Formula: C41H65NO10
Formula Weight: 731.96
MOL File: 168316-95-8.mol

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SPINOSAD Property

Melting point:: 110℃
storage temp.: 0-6°C
solubility: Ethanol: 1 mg/ml
form: Solid
color: White to off-white
EPA Substance Registry System: Spinosad (168316-95-8)

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Safety

Hazard Codes: N
Risk Statements: 50/53
Safety Statements: 61
RIDADR: UN3077 9/PG 3
WGK Germany: 3
Toxicity: LD50 in rats, mallard ducks, quail (mg/kg): >3600, >2000, >2000 orally (Crouse)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CRM51599
Product name: Spinosad
Purity: certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Packaging: 50 mg
Price: $372
Updated: 2025/07/31

Sigma-Aldrich

Product number: 33706
Product name: Spinosad
Packaging: 50mg
Price: $307
Updated: 2025/07/31

Cayman Chemical

Product number: 25649
Product name: Spinosad
Purity: ≥95%
Packaging: 5mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 25649
Product name: Spinosad
Purity: ≥95%
Packaging: 10mg
Price: $84
Updated: 2024/03/01

Cayman Chemical

Product number: 25649
Product name: Spinosad
Purity: ≥95%
Packaging: 25mg
Price: $172
Updated: 2024/03/01

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SPINOSAD Chemical Properties,Usage,Production

Description

Spinosad is a naturally-occurring insecticide found in the the soil bacterium S. spinosa. It is a mixture of the macrocyclic lactones spinosyn A and spinosyn D , which act as agonists of insect nicotinic acetylcholinesterase receptors (nAChRs). Oral administration of spinosad induces toxicity in fruit flies including C. capitata, B. curcurbitae, and B. dorsalis (LC₅₀s = 2.8-4.2, 4.3-5.5, and 3.1-3.3 μg/ml, respectively) but has low toxicity in vertebrates. It also inhibits canine P-glycoprotein (P-gp; IC₅₀ = 0.2 μg/ml). Formulations containing spinosad have been used in the agricultural and veterinary control of insects.

Uses

Insecticide.

Definition

Isolated from Saccharopolyspora spinosa (Actinomycetes).

Hazard

A poison by inhalation. Moderately toxic by ingestion.

in vivo

Spinosad is a natural mixture of the pediculicidal tetracyclic macrolides spinosyn A and spinosyn D. Spinosad 0.9% mainly interferes with nicotinic acetylcholine receptors in insects, thereby producing neuronal excitation that results in paralysis of lice from neuromuscular fatigue after extended periods of hyperexcitation. Spinosad 0.9% kills both permethrin-susceptible and permethrin-resistant populations of lice. It is also ovicidal, killing both eggs (nits) and lice^[5].
Spinosad causes in vivo oxidative effects in the brain of Oreochromis niloticus. Spinosad causes elevations in the contents of tGSH, GSH, GSSG, Hsp70, and reductions in the ratio of GSH/GSSG and GPx activity and an induction in the GR (glutathione reducta) activity. Spinosad has oxidative effects in the brain tissue by altering the parameters in GSH-related antioxidant system and Hsp70^[6].

References

[1] WESLEY J. MAGUIRE*. Comprehensive Determination of Unregulated Pesticide Residues in Oregon Cannabis Flower by Liquid Chromatography Paired with Triple Quadrupole Mass Spectrometry and Gas Chromatography Paired with Triple Quadrupole Mass Spectrometry[J]. Journal of Agricultural and Food Chemistry, 2019, 67 46: 12670-12674. DOI: 10.1021/acs.jafc.9b01559
[2] D. T. VO. Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals[J]. Journal of veterinary pharmacology and therapeutics, 2010, 33 4: 315-322. DOI: 10.1111/j.1365-2885.2010.01160.x
[3] JOHN D STARK Neil M Roger Vargas. Toxicity of spinosad in protein bait to three economically important tephritid fruit fly species (Diptera: Tephritidae) and their parasitoids (Hymenoptera: Braconidae).[J]. Journal of Economic Entomology, 2004, 97 3: 911-915. DOI: 10.1603/0022-0493(2004)097[0911:tosipb]2.0.co;2
[4] T S AMARAL. Short-term effects of a spinosyn’s family insecticide on energy metabolism and liver morphology in frugivorous bats Artibeus lituratus (Olfers, 1818).[J]. Brazilian Journal of Biology, 2012, 72 2: 299-304. DOI: 10.1590/s1519-69842012000200010
[5] SCHRICKX J A. Spinosad is a potent inhibitor of canine P-glycoprotein[J]. Veterinary journal, 2014, 200 1: Pages 195-196. DOI: 10.1016/j.tvjl.2014.01.012

SPINOSAD Preparation Products And Raw materials

Raw materials

Preparation Products

SPINOSAD Spinosad D

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SPINOSAD Suppliers

China 141 France 2 Germany 2 India 3 Japan 2 Switzerland 2 United Kingdom 4 United States 10 USA 1 Global 167

Hubei widely chemical technology Co., Ltd.

Tel: 027-83991130 18627774460
Fax: 027-83991130
Email: 1718093273@QQ.COM
Country: China
ProdList: 1676
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 7247
Advantage: 62

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Wuhan DKY Technology Co.,Ltd.

Tel: 027-27-81302488 15972195220
Fax: 027-81302088
Email: info@dkybpc.com
Country: China
ProdList: 1758
Advantage: 58

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View Lastest Price from SPINOSAD manufacturers

Wuhan Fortuna Chemical Co.,Ltd

Product: Spinosad 168316-95-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 90%-95%TC
Supply Ability: 20TONS
Release date: 2025-07-30

Hebei Chuanghai Biotechnology Co., Ltd

Product: Spinosad 168316-95-8
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-06

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: SPINOSAD 168316-95-8
Price: US $45.00/kg
Min. Order: 1kg
Purity: 95%
Supply Ability: 20ton
Release date: 2024-04-29

168316-95-8, SPINOSADRelated Search:

Monensin SPINOSAD 100MG [R] SPINOSAD SOLUTION 100UG/ML IN ACETONITRILE 1ML SPINOSAD SOLUTION 100UG/ML IN TOLUENE 1ML SPINOSAD

Mixture of Spinosyn A and Spinosyn D

Spinosad [iso]

Tracer naturalyte

SPINOS

Spinosad Standard

Spinosad @100 μg/mL in Acetonitrile

Spinosad@1000 μg/mL in Acetonitrile

Spinosad (Mixture of Spinosyn A and Spinosyn D)

Spinosad(MixofIsomers)Solution,10mg/L,10ml

SpinosadSolution,1000mg/L,1ml

48%SC Spinosad Insecticide 168316-95-8 Vegetable Garden Insecticides

168316-95-8 arochemical Biological Pesticides Spinosad Insecticide 48%SC

Spinosad Solution in Methanol, 100μg/mL

SPINOSAD USP/EP/BP

oxysaccharin

Spinosads

Spinosad in Acetone

C16972830 Spinosad

L16972830ALSpinosad 10μg/mLin Acetonitrile

Spinosad 10.0 μg/ml Acetonitrile

Reaction mass of Spinosyn A: (2R,3aS,5aR,5bS,9S,13S,14R,16aS,16bR)-2-(6-deoxy-2,3,4-tri-O-methyl-α-L-mannopyranosyloxy)-13-(4-dimethylamino-2,3,4,6-tetradeoxy-β-D-erythropyranosyloxy)-9-ethyl-2,3a,5a,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-14-methyl-1H-8-oxacyclododeaca[b]as-indacene-7,15-dione and Spinosyn D: (2R,3aS,5aR,5bS,9S,13S,14R,16aS,16bR)-2-(6-deoxy-2,3,4-tri-O-methyl-α-L-mannopyranosyloxy)-13-(4-dimethylamino-2.3.4.6-tetradeoxy-β-D-erythropyranosyloxy)-9-ethy-2,3

Spinosad as a mixture of 50-95 % spinosyn A and 5-50 % spinosyn D.

spinosad 2.5% SC10% SC 92.5% TC

Spinosad, 10 mM in DMSO

Spinosad - mixture of A + D

Spinosad (CRM)

Spinosad 10 μg/mL in Acetonitrile

Oregon Pesticide Mixture 1 600 μg/mL in Acetonitrile

168316-95-8

31929-60-7

C83H132N2O20

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