5-METHYL-DL-TRYPTOPHAN
- Product Name
- 5-METHYL-DL-TRYPTOPHAN
- CAS No.
- 951-55-3
- Chemical Name
- 5-METHYL-DL-TRYPTOPHAN
- Synonyms
- H-Trp(5-Me)-OH;H-5-ME-DL-TRP-OH;H-DL-Trp(5-Me)-OH;TIMTEC-BB SBB003368;5-METHYL-DL-TRYPTOPH;DL-5-METHYLTRYPTOPHAN;5-METHYL-DL-TRYPTOPHAN;5-Methyl-DL-tryptophan>5-Methyl-DL-tryptophan,98%;5-METHYL-DL-TRYPTOPHAN USP/EP/BP
- CBNumber
- CB5417694
- Molecular Formula
- C12H14N2O2
- Formula Weight
- 218.25
- MOL File
- 951-55-3.mol
5-METHYL-DL-TRYPTOPHAN Property
- Melting point:
- ~275 °C (dec.)
- Boiling point:
- 358.94°C (rough estimate)
- alpha
- [α]D20 -1~+1゜ (c=1, dil. HCl)
- Density
- 1.1402 (rough estimate)
- refractive index
- 1.6660 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- form
- Powder
- pka
- 2.26±0.10(Predicted)
- color
- Off-white
- BRN
- 20225
- CAS DataBase Reference
- 951-55-3(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- M0534
- Product name
- 5-Methyl-DL-tryptophan
- Purity
- tryptophan analog
- Packaging
- 250mg
- Price
- $257
- Updated
- 2024/03/01
- Product number
- M0534
- Product name
- 5-Methyl-DL-tryptophan
- Purity
- tryptophan analog
- Packaging
- 1g
- Price
- $510
- Updated
- 2024/03/01
- Product number
- M0452
- Product name
- 5-Methyl-DL-tryptophan
- Purity
- >98.0%(T)(HPLC)
- Packaging
- 100mg
- Price
- $69
- Updated
- 2024/03/01
- Product number
- M0452
- Product name
- 5-Methyl-DL-tryptophan
- Purity
- >98.0%(T)(HPLC)
- Packaging
- 1g
- Price
- $563
- Updated
- 2024/03/01
- Product number
- 284106
- Product name
- 5-Methyl-DL-tryptophan
- Packaging
- 250mg
- Price
- $375
- Updated
- 2021/12/16
5-METHYL-DL-TRYPTOPHAN Chemical Properties,Usage,Production
Chemical Properties
off-white powder
Definition
ChEBI: 5-methyltryptophan is a tryptophan derivative that is tryptophan substituted by a methyl group at position 5 of the indole ring. It is a non-proteinogenic alpha-amino acid and a tryptophan derivative.
Biological Activity
5-Methyl-DL-tryptophan inhibits the synthesis of anthranilate compounds th at are the first steps in the biosynthesis of tryptophan in Neurospora crassa. 5-Methyl-DL-tryptophan is a corepressor of the E. coli trp repressor.', '5-Methyl-DL-tryptophan may be used to select genetic mutants of PS strain of Methanococcus voltae (archaebacteria). 5-Methyl-tryptophan is a repressor trp operon expression. 5-Methyl-tryptophan is a substrate for tryptophanase. 5-Methyl-tryptophan inhibits the induction of anthranilate synthase activity by elicitors in oats.
Purification Methods
Crystallise dl-5-methyltryptophan from aqueous EtOH after dissolving it in aqueous NaOH, precipitating with AcOH, filtering the solid off and drying for 24hours at 50o. [Jackman & Archer J Am Chem Soc 68 2105 1946, Beilstein 22 IV 6815.] The picrate crystallises from MeOH with m 202o(dec). The N-phenylcarbamoyl derivative crystallises from aqueous MeOH with m 202o. [Gordon & Jackson J Biol Chem 110 151, 154 1935.]
5-METHYL-DL-TRYPTOPHAN Preparation Products And Raw materials
Raw materials
Preparation Products
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