4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE

Product Name: 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE
CAS No.: 26956-43-4
Chemical Name: 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE
Synonyms: 108561;Furo[3,2-c]pyridin-4-ol;5H-Furo[3,2-c]pyridin-4-one;FURO[3,2-C]PYRIDIN-4(5H)-ONE;4H,5H-furo[3,2-c]pyridin-4-one;4,5-Dihyro-4-Oxofuro[3,2]Pyridine;4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE;4-OXO-4,5-DIHYDROFURO[3,2-C]PYRIDINE;Furo[3,2-c]pyridin-4(5H)-one (8CI, 9CI, ACI);4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE ISO 9001：2015 REACH
CBNumber: CB5428634
Molecular Formula: C7H5NO2
Formula Weight: 135.12
MOL File: 26956-43-4.mol

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4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE Property

Melting point:: 202-204 °C
Boiling point:: 372.8±42.0 °C(Predicted)
Density: 1.288±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 12.11±0.20(Predicted)
Appearance: Light yellow to yellow Solid
InChI: InChI=1S/C7H5NO2/c9-7-5-2-4-10-6(5)1-3-8-7/h1-4H,(H,8,9)
InChIKey: FYNCIYHECMWXPK-UHFFFAOYSA-N
SMILES: C1(=O)NC=CC2OC=CC1=2

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: 2811
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CVT00122
Product name: Furo[3,2-c]pyridin-4-ol
Packaging: 1g
Price: $958
Updated: 2023/06/20

TRC

Product number: F864853
Product name: Furo[3,2-c]pyridin-4(5H)-one
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 070257
Product name: Furo[3,2-c]pyridin-4(5H)-one
Purity: 95%
Packaging: 1g
Price: $63
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H48-1-E2
Product name: Furo[3,2-c]pyridin-4(5H)-one
Packaging: 1g
Price: $72
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD139854
Product name: 4,5-dihydro-4-oxofuro[3,2-c]pyridine
Packaging: 500mg
Price: $160
Updated: 2021/12/16

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4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE Chemical Properties,Usage,Production

Synthesis

119924-26-4

26956-43-4

The general procedure for the synthesis of 4,5-dihydro-4-oxofuro[3,2]pyridine from (E)-3-(furan-2-yl)acryloyl azide was as follows: (E)-3-(furan-2-yl)acryloyl azide (150 g, 920 mmol) was added to toluene (800 mL) preheated to 100 °C and the reaction mixture was stirred for 30 min. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in o-dichlorobenzene (800 mL) and iodine (1 g) was added as a catalyst. The reaction mixture was stirred at 180 °C for 2 h, followed by evaporation under reduced pressure to remove the solvent. The residue was dissolved in methanol, the precipitate was collected by filtration and the filtrate was concentrated under reduced pressure. Finally, the residue was washed with diisopropyl ether to afford the target product 4,5-dihydro-4-oxofuro[3,2]pyridine (100 g, 80% yield). The product was characterized by 1H-NMR (DMSO-d6): δ 6.85 (1H, dd, J = 7.1, 1.0 Hz), 6.92 (1H, dd, J = 1.9, 1.0 Hz), 7.29 (1H, d, J = 7.1 Hz), 7.86 (1H, d, J = 1.9 Hz), 11.42 (1H, brs).

References

[1] Patent: EP2100895, 2009, A1. Location in patent: Page/Page column 44
[2] Patent: WO2013/163244, 2013, A1. Location in patent: Paragraph 00273
[3] Patent: WO2016/37578, 2016, A1. Location in patent: Page/Page column 146
[4] Patent: WO2004/100947, 2004, A2. Location in patent: Page 20-21; 16
[5] Patent: WO2005/67900, 2005, A2. Location in patent: Page/Page column 39-40

4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE Suppliers

China 89 Germany 3 India 1 The Netherlands 1 United Kingdom 4 United States 12 Global 110

Shanghai TBBMed Co.,Ltd

Tel: 021-50498136 13564881053
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Email: products@tbbmed.com
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Shaoyuan Technology (Shanghai) Co., Ltd.

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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Capot Chemical Co., Ltd

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Shangchem Co., Ltd.

Tel: +86-21-68182121
Fax: +86-21-68182121
Country: China
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Shanghai Hanhong Scientific Co.,Ltd.

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China DongFan Chemical Co.,LTD

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Shanghai Ennopharm Co., Ltd.

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Syntechem Co.,Ltd

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China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
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View Lastest Price from 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE 26956-43-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-12

Career Henan Chemical Co

Product: 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE 26956-43-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-07-11

26956-43-4, 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINERelated Search:

Furo[3,4-c]pyridin-1(3h)-one furo[3,2-b]pyridine 4-(2-Nitrophenyl)-2-methyl-5,7-dihydro-5-oxofuro[3,4-b]pyridine-3-carboxylic acid methyl ester 4-(2,3-Dichlorophenyl)-2-methyl-5,7-dihydro-5-oxofuro[3,4-b]pyridine-3-carboxylic acid 2-[2-(Trifluoromethyl)phenyl]-4-methyl-5,7-dihydro-5-oxofuro[3,4-b]pyridine-3-carboxylic acid methyl ester 5-AMINO-6-METHYLFURO[3,2-C]PYRIDIN-4(5H)-ONE 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE SALOR-INT L299502-1EA SALOR-INT L299510-1EA SALOR-INT L299529-1EA

FURO[3,2-C]PYRIDIN-4(5H)-ONE

4-OXO-4,5-DIHYDROFURO[3,2-C]PYRIDINE

4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE

4,5-Dihyro-4-Oxofuro[3,2]Pyridine

4H,5H-furo[3,2-c]pyridin-4-one

5H-Furo[3,2-c]pyridin-4-one

Furo[3,2-c]pyridin-4-ol

108561

4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE ISO 9001：2015 REACH

Furo[3,2-c]pyridin-4(5H)-one (8CI, 9CI, ACI)

26956-43-4

Fused Ring Systems