Preparation
ChemicalBook > CAS DataBase List > 1-METHYL-5-NITRO-ISATIN

1-METHYL-5-NITRO-ISATIN

Preparation
Product Name
1-METHYL-5-NITRO-ISATIN
CAS No.
3484-32-0
Chemical Name
1-METHYL-5-NITRO-ISATIN
Synonyms
1-METHYL-5-NITRO-ISATIN;1-METHYL-5-NITROINDOLINE-2,3-DIONE;1H-Indole-2,3-dione, 1-methyl-5-nitro-
CBNumber
CB5431395
Molecular Formula
C9H6N2O4
Formula Weight
206.15
MOL File
3484-32-0.mol
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1-METHYL-5-NITRO-ISATIN Property

storage temp. 
Sealed in dry,Room Temperature
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Alichem
Product number
3484320
Product name
1-Methyl-5-nitroindoline-2,3-dione
Packaging
1g
Price
$386.9
Updated
2021/12/16
Chemenu
Product number
CM242343
Product name
1-Methyl-5-nitroindoline-2,3-dione
Purity
95%
Packaging
1g
Price
$422
Updated
2021/12/16
Crysdot
Product number
CD11138706
Product name
1-Methyl-5-nitroindoline-2,3-dione
Purity
95+%
Packaging
1g
Price
$447
Updated
2021/12/16
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1-METHYL-5-NITRO-ISATIN Chemical Properties,Usage,Production

Preparation

A mixture of nitroisatin 31 (10 g, 0.052 mol), MeI (16.21 ml, 0.260  mol) and K2CO3 (21.56 g, 1.56 mol) in anhydrous DMF was stirred  overnight at room temperature. Water was added to the reaction  mixture and acidified with dilute HCl till acidic to pH paper. A  yellow solid separated, 1-Methyl-5-nitroisatin was filtered and washed thoroughly  with water till neutral to pH paper and air dried to a constant weight (9.66 g).

Synthesis Reference(s)

Journal of Medicinal Chemistry, 39, p. 5072, 1996 DOI: 10.1021/jm960603e

1-METHYL-5-NITRO-ISATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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1-METHYL-5-NITRO-ISATIN Suppliers

China 19 France 1 United Kingdom 2 United States 3 Global 25
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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3484-32-0, 1-METHYL-5-NITRO-ISATINRelated Search:

5-Nitroisatin Isatin 2-(5-nitro-2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetonitrile 1-(2,4-DICHLOROBENZYL)-5-NITRO-1H-INDOLE-2,3-DIONE 4H-PYRROLO[3,2,1-IJ]QUINOLINE-1,2-DIONE, 5,6-DIHYDRO-8-NITRO- 1-ethyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione 1-(2-bromoethyl)-5-nitro-2,3-dihydro-1H-indole-2,3-dione 5-nitro-1-(prop-2-en-1-yl)-2,3-dihydro-1H-indole-2,3-dione 5-NITRO-1-(PHENYLMETHYL)-ISATIN 5-nitro-1-propyl-2,3-dihydro-1H-indole-2,3-dione 1-METHYL-5-NITRO-ISATIN 1-(2-hydroxyethyl)-5-nitro-2,3-dihydro-1H-indole-2,3-dione (5-nitro-2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetic acid 5-nitro-1-(prop-2-yn-1-yl)-2,3-dihydro-1H-indole-2,3-dione 1-(4-CHLOROBENZYL)-5-NITRO-1H-INDOLE-2,3-DIONE 1-ACETYL-7-METHYL-5-NITRO-1H-INDOLE-2,3-DIONE

  • 1-METHYL-5-NITRO-ISATIN
  • 1-METHYL-5-NITROINDOLINE-2,3-DIONE
  • 1H-Indole-2,3-dione, 1-methyl-5-nitro-
  • 3484-32-0
  • pharmacetical