Preparation
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5-Nitroisatin

Preparation
Product Name
5-Nitroisatin
CAS No.
611-09-6
Chemical Name
5-Nitroisatin
Synonyms
NSC 525798;Nitroisatin;AKOS B022561;5-Nitrosotin;5-nitro-isati;5-NITROISATIN;Isatin, 5-nitro-;5-Nitroisatin>AKOS BBS-00006405;5-Nitroisatin,97%
CBNumber
CB3396128
Molecular Formula
C8H4N2O4
Formula Weight
192.13
MOL File
611-09-6.mol
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5-Nitroisatin Property

Melting point:
251 °C (dec.) (lit.)
Boiling point:
328.09°C (rough estimate)
Density 
1.5513 (rough estimate)
refractive index 
1.4900 (estimate)
storage temp. 
Sealed in dry,Room Temperature
pka
8.06±0.20(Predicted)
form 
Crystalline Powder
color 
Orange-yellow to orange
BRN 
180223
InChIKey
UNMYHYODJHKLOC-UHFFFAOYSA-N
CAS DataBase Reference
611-09-6(CAS DataBase Reference)
NIST Chemistry Reference
1H-indole-2,3-dione, 5-nitro-(611-09-6)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-40-68-22
Safety Statements 
7-22-36/37/39-45-36/37
RIDADR 
2811
WGK Germany 
3
RTECS 
NL7970000
HazardClass 
IRRITANT
HS Code 
29337900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H351Suspected of causing cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N17807
Product name
5-Nitroisatin
Purity
97%
Packaging
5g
Price
$86.2
Updated
2024/03/01
Sigma-Aldrich
Product number
N17807
Product name
5-Nitroisatin
Purity
97%
Packaging
25g
Price
$306
Updated
2023/06/20
TCI Chemical
Product number
N0572
Product name
5-Nitroisatin
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
N0572
Product name
5-Nitroisatin
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$144
Updated
2024/03/01
Alfa Aesar
Product number
B24962
Product name
5-Nitroisatin, 98%
Packaging
5g
Price
$36.65
Updated
2024/03/01
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5-Nitroisatin Chemical Properties,Usage,Production

Preparation

Isatin 30 (14.7 g, 0.1 mol) was added to conc. H2SO4 (121 ml)  cooled to 0 ºC in an ice-salt bath. Fuming HNO3 (4.2 ml) was  added to this, drop by drop, in such a way that temperature should  not rise above 5 ºC. The reaction mixture was allowed to stand for  about 30 minutes and then poured over crushed ice (500 g). A yellow precipitate separated  immediately. The 5-Nitroisatin was filtered and washed with water and air dried to a constant  weight (15 g).  Yield : 85%

Chemical Properties

orange-yellow to orange crystalline powder

Uses

Reactant for preparation of:

  • Potential antibacterial and antifungal agents
  • spiro[indole-thiazolidinones] as a medicinally important scaffold
  • Potential antimycobacterial agents
  • Anticonvulsant agents
  • Inhibitors of human transglutaminase 2
  • Anthelmintic agents
  • Anti-human immunodeficiency virus (HIV) agents
  • Antimicrobial agents
  • Potential antitubercular agents
  • Inhibitors of acetylcholinesterase

Definition

ChEBI: 5-Nitroisatin is a member of indoles. It has a role as an anticoronaviral agent.

5-Nitroisatin Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Nitroisatin Suppliers

Nanjing LuoDa Chemical Co., Ltd
Tel
025-66016961 13382082786
Fax
025-52204547
Country
China
ProdList
291
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
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View Lastest Price from 5-Nitroisatin manufacturers

Wuhan KEMI-WORKS Chemical Co., Ltd.
Product
5-Nitroisatin 611-09-6
Price
US $0.00/kg
Min. Order
1kg
Purity
98.0% min
Supply Ability
10tons
Release date
2024-08-06
Hebei Chuanghai Biotechnology Co,.LTD
Product
5-Nitroisatin 611-09-6
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-21
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-nitro-1H-indole-2,3-dione 611-09-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26

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