Preparation
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5-Nitroisatin

Preparation
Product Name
5-Nitroisatin
CAS No.
611-09-6
Chemical Name
5-Nitroisatin
Synonyms
NSC 525798;Nitroisatin;AKOS B022561;5-Nitrosotin;5-nitro-isati;5-NITROISATIN;Isatin, 5-nitro-;5-Nitroisatin>AKOS BBS-00006405;5-Nitroisatin,97%
CBNumber
CB3396128
Molecular Formula
C8H4N2O4
Formula Weight
192.13
MOL File
611-09-6.mol
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5-Nitroisatin Property

Melting point:
251 °C (dec.) (lit.)
Boiling point:
328.09°C (rough estimate)
Density 
1.5513 (rough estimate)
refractive index 
1.4900 (estimate)
storage temp. 
Sealed in dry,Room Temperature
pka
8.06±0.20(Predicted)
form 
Crystalline Powder
color 
Orange-yellow to orange
BRN 
180223
InChIKey
UNMYHYODJHKLOC-UHFFFAOYSA-N
CAS DataBase Reference
611-09-6(CAS DataBase Reference)
NIST Chemistry Reference
1H-indole-2,3-dione, 5-nitro-(611-09-6)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-40-68-22
Safety Statements 
7-22-36/37/39-45-36/37
RIDADR 
2811
WGK Germany 
3
RTECS 
NL7970000
HazardClass 
IRRITANT
HS Code 
29337900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H351Suspected of causing cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N17807
Product name
5-Nitroisatin
Purity
97%
Packaging
5g
Price
$86.2
Updated
2024/03/01
Sigma-Aldrich
Product number
N17807
Product name
5-Nitroisatin
Purity
97%
Packaging
25g
Price
$306
Updated
2023/06/20
TCI Chemical
Product number
N0572
Product name
5-Nitroisatin
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
N0572
Product name
5-Nitroisatin
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$144
Updated
2024/03/01
Alfa Aesar
Product number
B24962
Product name
5-Nitroisatin, 98%
Packaging
5g
Price
$36.65
Updated
2024/03/01
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5-Nitroisatin Chemical Properties,Usage,Production

Preparation

Isatin 30 (14.7 g, 0.1 mol) was added to conc. H2SO4 (121 ml)  cooled to 0 ºC in an ice-salt bath. Fuming HNO3 (4.2 ml) was  added to this, drop by drop, in such a way that temperature should  not rise above 5 ºC. The reaction mixture was allowed to stand for  about 30 minutes and then poured over crushed ice (500 g). A yellow precipitate separated  immediately. The 5-Nitroisatin was filtered and washed with water and air dried to a constant  weight (15 g).  Yield : 85%

Chemical Properties

orange-yellow to orange crystalline powder

Uses

Reactant for preparation of:

  • Potential antibacterial and antifungal agents
  • spiro[indole-thiazolidinones] as a medicinally important scaffold
  • Potential antimycobacterial agents
  • Anticonvulsant agents
  • Inhibitors of human transglutaminase 2
  • Anthelmintic agents
  • Anti-human immunodeficiency virus (HIV) agents
  • Antimicrobial agents
  • Potential antitubercular agents
  • Inhibitors of acetylcholinesterase

Definition

ChEBI: 5-Nitroisatin is a member of indoles. It has a role as an anticoronaviral agent.

5-Nitroisatin Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Nitroisatin Suppliers

TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
ecochem international chemical broker
Tel
--
Fax
--
Email
export@ecochem.dk
Country
Europe
ProdList
6371
Advantage
66
kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47
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View Lastest Price from 5-Nitroisatin manufacturers

Wuhan KEMI-WORKS Chemical Co., Ltd.
Product
5-Nitroisatin 611-09-6
Price
US $0.00/kg
Min. Order
1kg
Purity
98.0% min
Supply Ability
10tons
Release date
2024-08-06
Hebei Chuanghai Biotechnology Co,.LTD
Product
5-Nitroisatin 611-09-6
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-21
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-nitro-1H-indole-2,3-dione 611-09-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26

611-09-6, 5-NitroisatinRelated Search:


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