ChemicalBook > CAS DataBase List > 1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE

1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE

Product Name
1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE
CAS No.
52099-72-6
Chemical Name
1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE
Synonyms
IFLAB-BB F0451-0304;TIMTEC-BB SBB006406;ISOPROPENYL-BENZIMID;Flibanserin Impurity 10;Domperidone Impurity 22;Domperidone Impurity 33;N-Isopropenyl-2-benzimidazolone;1-Isopropenyl-2-benzimidazolone;ISOPROPENYL-BENZIMIDAZOLIDINONE-2;2-BENZIMIDAZOLINONE,1-ISOPROPENYL
CBNumber
CB5432958
Molecular Formula
C10H10N2O
Formula Weight
174.2
MOL File
52099-72-6.mol
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1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE Property

Melting point:
120-124 °C
Boiling point:
305.17°C (rough estimate)
Density 
1.1455 (rough estimate)
refractive index 
1.6300 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
11.72±0.30(Predicted)
form 
Crystalline Powder
color 
White to slightly cream
BRN 
140587
InChI
InChI=1S/C10H10N2O/c1-7(2)12-9-6-4-3-5-8(9)11-10(12)13/h3-6H,1H2,2H3,(H,11,13)
InChIKey
XFASJWLBXHWUMW-UHFFFAOYSA-N
SMILES
C1(=O)N(C(C)=C)C2=CC=CC=C2N1
CAS DataBase Reference
52099-72-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,T
Risk Statements 
22-25
Safety Statements 
22-24/25-45
RIDADR 
UN 2810 6.1/PG 3
WGK Germany 
3
HazardClass 
6.1
HS Code 
29339980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
679402
Product name
1-Isopropenyl-2-benzimidazolidinone
Purity
97%
Packaging
5g
Price
$84.48
Updated
2025/07/31
Sigma-Aldrich
Product number
679402
Product name
1-Isopropenyl-2-benzimidazolidinone
Purity
97%
Packaging
1g
Price
$41.1
Updated
2023/06/20
TCI Chemical
Product number
I1127
Product name
1-Isopropenyl-2-benzimidazolidinone
Purity
min. 98.0 %
Packaging
5G
Price
$73
Updated
2025/07/31
TCI Chemical
Product number
I1127
Product name
1-Isopropenyl-2-benzimidazolidinone
Purity
min. 98.0 %
Packaging
25G
Price
$218
Updated
2025/07/31
AK Scientific
Product number
7318AB
Product name
1-Isopropenyl-2-benzimidazolidinone
Packaging
10g
Price
$158
Updated
2021/12/16
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1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Solid

Synthesis

141-97-9

95-54-5

52099-72-6

General procedure for the synthesis of 1,3-dihydro-1-(1-methylethynyl)-2H-benzimidazol-2-one from ethyl acetoacetate and o-phenylenediamine: 50 grams of o-phenylenediamine, 90 grams of ethyl acetoacetate, and 5 grams of sodium hydroxide were dissolved in 300 ml of o-xylene. The reaction was refluxed at 130°C for about 7 hours, during which time the water generated was removed by means of a water separator. Upon completion of the reaction, the reaction mixture was cooled to 80 °C and washed twice with 100 ml of water to remove water-soluble impurities. Subsequently, the mixture was cooled to 0 °C to allow the target product to precipitate as a white solid. The solid product was collected by filtration and dried to give 65 g of 1,3-dihydro-1-(1-methylethynyl)-2H-benzimidazol-2-one (DOM-2) in 94% yield.

References

[1] Patent: CN108129396, 2018, A. Location in patent: Paragraph 0022; 0023; 0033; 0034
[2] Bulletin des Societes Chimiques Belges, 1987, vol. 96, # 10, p. 787 - 792
[3] Patent: CN102816121, 2016, B. Location in patent: Paragraph 0022-0024
[4] Journal of Chemical Research - Part S, 1996, # 2, p. 92 - 93
[5] Russian Journal of Physical Chemistry A, 2015, vol. 89, # 5, p. 807 - 811

1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE Suppliers

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View Lastest Price from 1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE manufacturers

Career Henan Chemical Co
Product
1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE 52099-72-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-07-01

52099-72-6, 1-ISOPROPENYL-2-BENZIMIDAZOLIDINONERelated Search:

1,3-dihydro-4-methyl-2H-1,5-benzodiazepin-2-one Flibanserin-d4 Flibanserin 1-ACETYL-2-METHYLBENZIMIDAZOLE 1-(3-Trifluoromethylphenyl)piperazine hydrochloride 1-(prop-1-en-2-yl)-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1H-benzo[d]imidazol-2(3H)-one 3,3'-(ethane-1,2-diyl)bis(1-(2-chloroethyl)-1H-benzo[d]imidazol-2(3H)-one) 1,2-bis(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethane Flibanserin Hydrochloride 4-methyl-1H-benzo[b][1,4]diazepin-2(3H)-one 1,3-bis(2-chloroethyl)benzimidazolin-2-one DROPERIDOL 1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE 1,3-DIHYDRO-1-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-2H-BENZIMIDAZOLE-2-ONE 1-[1-(CYCLOOCTYLMETHYL)-1,2,3,6-TETRAHYDRO-5-(HYDROXYMETHYL)-4-PYRIDINYL]-3-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE HYDROCHLORIDE 2H-BENZIMIDAZOL-2-ONE, 1,3-DIHYDRO-1-(2-HYDROXYETHYL)-3-(1-METHYLETHENYL)- 4-(3-ISOPROPENYL-2-OXO-2,3-DIHYDRO-1H-1,3-BENZIMIDAZOL-1-YL)BUTANOIC ACID 1-(1-BENZYL-1,2,3,6-TETRAHYDRO-PYRIDIN-4-YL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE

  • 3-Isopropenyl-1H-benzimidazole-2(3H)-one
  • 1-(prop-1-en-2-yl)-1H-benzo(d)imidazol-2(3H)-one
  • 1-Isopropyl-2-benzimidazolidinone,99%
  • N-Isopropenyl-2-benzimidazolone
  • 1-Isopropyl-2-benzimidazolidinone, 99%
  • 2H-BenziMidazol-2-one, 1,3-dihydro-1-(1-Methylethenyl)-
  • 1-(2-Propenyl)-1,3-dihydro-benziMidazol-2H-one
  • 1-lsopropenyl-2-benziMidazolidinone
  • -(2-PROPENYL)-2-BENZIMIDAZOLIDINONE
  • 1,3-dihydro-1 - (1-methylethynyl) - 2h-benzimidazole-2-one
  • 1-(2-PROPENYL)-2-BENZIMIDAZOLIDINONE
  • 1,3-DIHYDRO-1-(1-METHYLETHENYL)-2H-BENZIMIDAZOLE-2-ONE
  • 1-ISOPROPENYL-1,3-DIHYDRO-2H-1,3-BENZIMIDAZOL-2-ONE
  • 1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE
  • ISOPROPENYL-BENZIMIDAZOLIDINONE-2
  • IFLAB-BB F0451-0304
  • TIMTEC-BB SBB006406
  • 1-(methylvinyl)-1H-benzimidazol-2(3H)-one
  • 1-Isopropenyl-1H-benzimidazol-2(3H)-one
  • 1,3-dihydro-1-(1-methylvinyl)-2H-benzimidazol-2-one
  • 1,3-Dihydro-1-(1-Methylethenyl)-2H-Benzimidazol-2-One
  • 1,3-Dihydro-1-(1-methylvinyl)-2H-benzimidazol-2-on
  • 1,3-DIHYDRO-1-(1-METHYLETHENYL)-2H-BENZIMIDAZOLE-2-ONE 99%
  • 2-BENZIMIDAZOLINONE,1-ISOPROPENYL
  • 2H-Benzimidazol-2-one,1,3-dihydro-1-(1-methylethenyl)-(9CI)
  • 1-Isopropenyl-2-benzimidazolidinone, 98+%
  • 1,3-Dihydro-1-(1-methylethenyl)-2H-benzimidazole-2-one, 1-(2-Propenyl)-2-benzimidazolidinone
  • 1-(prop-1-en-2-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
  • Flibanserin Impurity 10
  • 1,3- dihydro-1-(1-methylacetylene)-2H-benzimidazole-2-ketone
  • ISOPROPENYL-BENZIMID
  • 1-(2-Propen-2-yl)-2-benzimidazolidinone
  • 1-Isopropenyl-2-benzimidazolone
  • Domperidone Impurity 22
  • 1-(porp-1-en-2-yl)-1H-benzo{d}-imidazol-2-(3H)-one
  • Domperidone Impurity 33
  • 52099-72-6
  • 52099-72-9
  • 72798-66-8
  • Aromatics
  • Aromatics Compounds
  • Imidaxoles
  • BENZIMIDAZOLE