Flibanserin Hydrochloride

Product Name: Flibanserin Hydrochloride
CAS No.: 147359-76-0
Chemical Name: Flibanserin Hydrochloride
Synonyms: Flibanserin HCl;Flibanserin iMpurity;Flibanserin Hydrochloride;Flibanserin Hydrochloride USP/EP/BP;Flibanserin hydrochloride (propan-2-ol) hydrate;2H-Benzimidazol-2-one,1,3-dihydro-1-[2-[4-[3-(trifluoromethy...;1-(2-(4-(3-(TFMl)Phnyl)Piprzin-1yl)-etyl)-1H-bnz(d)Imdl-2-(3H)-one HCl;1-(2-(4-(3-(Trifluoromethyl) Phenyl) Piperazin-1yl)-ethyl)-1H-benzo (d) Imidazol-2-(3H)-one HCl;1-(2-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one hydrochloride;2H-Benzimidazol-2-one,1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-,hydrochloride (1:1)
CBNumber: CB82724043
Molecular Formula: C20H22ClF3N4O
Formula Weight: 426.87
MOL File: 147359-76-0.mol

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Flibanserin Hydrochloride Property

Melting point:: >225°C (dec.)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Pale Yellow
InChI: InChI=1S/C20H21F3N4O.ClH/c21-20(22,23)15-4-3-5-16(14-15)26-11-8-25(9-12-26)10-13-27-18-7-2-1-6-17(18)24-19(27)28;/h1-7,14H,8-13H2,(H,24,28);1H
InChIKey: XGAGFLQFMFCIHZ-UHFFFAOYSA-N
SMILES: C(N1C(NC2C=CC=CC1=2)=O)CN1CCN(C2C=CC=C(C(F)(F)F)C=2)CC1.Cl

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: F401270
Product name: FlibanserinHydrochloride
Packaging: 10mg
Price: $135
Updated: 2021/12/16

TRC

Product number: F401270
Product name: FlibanserinHydrochloride
Packaging: 250mg
Price: $425
Updated: 2021/12/16

AK Scientific

Product number: 3584CR
Product name: Flibanserinhydrochloride
Packaging: 250mg
Price: $126
Updated: 2021/12/16

AK Scientific

Product number: 3584CR
Product name: Flibanserinhydrochloride
Packaging: 1g
Price: $141
Updated: 2021/12/16

AK Scientific

Product number: 3584CR
Product name: Flibanserinhydrochloride
Packaging: 5g
Price: $303
Updated: 2021/12/16

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Flibanserin Hydrochloride Chemical Properties,Usage,Production

Uses

Flibanserin is a 5-HT1A agonist and 5-HT2A antagonist that is developed for the treatment of hypoactive sexual desire disorder in women (1,2).

Synthesis

The one-pot reaction of benzaldehyde, N-phenylhydroxylamine and trimethylcyanosilane facilitated by iodobenzene acetate first builds the important backbone benzimidazolone structure of flubanserin, and then reacts with 1,2-dibromoethane to give intermediate 8, which is then hydrolyzed in concentrated hydrochloric acid to give intermediate 9, and then finally reacts with piperazine hydrochloride10 to give flubanserin in a total yield of 29%.11 The formation of salts of flubanserin with hydrochloric acid gives flubanserin hydrochloride. Flubanserin hydrochloride is formed by salting flubanserin with hydrochloric acid. This method is characterized by low cost and easy availability of raw materials, few by-products and high yield.

Flibanserin Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Flibanserin Hydrochloride Suppliers

China 81 India 3 United States 5 Global 89

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

ShangHai Caerulum Pharma Discovery Co., Ltd.

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Country: China
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Advantage: 58

Wuhan Dahua Pharmaceutical Co., Ltd.

Tel: 027-59262863 13277907145 3091977954
Fax: 027-59420980
Country: China
ProdList: 4942
Advantage: 58

Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd.

Tel: 027-59420981,18702770802
Fax: 027-83322098
Country: China
ProdList: 1975
Advantage: 50

Huangshi Healthday Pharmaceutical Technology Co.,Ltd.

Tel: 0714-0714-6352055 15897769779
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Email: sales@healthdaychem.com
Country: China
ProdList: 88
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

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Fax: QQ:3008007432
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Country: China
ProdList: 86249
Advantage: 60

Shanghai QianYan Bio-technology Co., Ltd

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Country: China
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Shenzhen Simeiquan Biotechnology Co. Ltd

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Country: China
ProdList: 5113
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
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Country: China
ProdList: 131957
Advantage: 58

Wuhan Magic Biological Technology Co., Ltd.

Tel: 18872289958、027-52304252、3400508168
Fax: 027-52304252
Email: 3400508168@qq.com
Country: China
ProdList: 1910
Advantage: 55

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View Lastest Price from Flibanserin Hydrochloride manufacturers

Firsky International Trade (Wuhan) Co., Ltd

Product: Flibanserin Hydrochloride 147359-76-0
Price: US $30.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2023-09-26

Baoji Guokang Healthchem co.,ltd

Product: Flibanserin Hydrochloride 147359-76-0
Price: US $1350.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 1000kg
Release date: 2021-06-04

WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD

Product: Flibanserin Hydrochloride 147359-76-0
Price: US $1.00/g
Min. Order: 10g
Purity: 98.5-99.9%HPLC,USP36
Supply Ability: 200kgs
Release date: 2020-10-14

147359-76-0, Flibanserin HydrochlorideRelated Search:

1,3-dihydro-4-methyl-2H-1,5-benzodiazepin-2-one Flibanserin-d4 Flibaserin Flibanserin 1-(prop-1-en-2-yl)-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1H-benzo[d]imidazol-2(3H)-one 3,3'-(ethane-1,2-diyl)bis(1-(2-chloroethyl)-1H-benzo[d]imidazol-2(3H)-one) 1-ACETYL-2-METHYLBENZIMIDAZOLE 1,3-bis(2-chloroethyl)benzimidazolin-2-one 1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE 4-methyl-1H-benzo[b][1,4]diazepin-2(3H)-one 1,2-bis(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethane 1-(3-Trifluoromethylphenyl)piperazine hydrochloride N-(3-Trifluoromethylphenyl)piperazine

Flibanserin Hydrochloride

Flibanserin HCl

Flibanserin iMpurity

2H-Benzimidazol-2-one,1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-,hydrochloride (1:1)

Flibanserin Hydrochloride USP/EP/BP

2H-Benzimidazol-2-one,1,3-dihydro-1-[2-[4-[3-(trifluoromethy...

1-(2-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one hydrochloride

1-(2-(4-(3-(Trifluoromethyl) Phenyl) Piperazin-1yl)-ethyl)-1H-benzo (d) Imidazol-2-(3H)-one HCl

1-(2-(4-(3-(TFMl)Phnyl)Piprzin-1yl)-etyl)-1H-bnz(d)Imdl-2-(3H)-one HCl

Flibanserin hydrochloride (propan-2-ol) hydrate

147359-76-0

C20H21F3N4OClH

C20H21F3N4OHCl