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N-(3-Trifluoromethylphenyl)piperazine

Product Name
N-(3-Trifluoromethylphenyl)piperazine
CAS No.
15532-75-9
Chemical Name
N-(3-Trifluoromethylphenyl)piperazine
Synonyms
TFTP;AKOS BBS-00003586;RARECHEM AH CK 0203;LABOTEST-BB LT00044462;1-(3-Methoxyphenyl)pipera;Flibanserin Impurity 2 Monomer;1-(3-TRIFLUOROMETHYL)-PIPERAZINE;3-(1-piperazino)benzotrifluoride;1-(3-Trifloromethyphenyl)piperazin;N-(3-TRIFLUOROMETHYLPHENYL)PIPERAZINE
CBNumber
CB0286059
Molecular Formula
C11H13F3N2
Formula Weight
230.23
MOL File
15532-75-9.mol
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N-(3-Trifluoromethylphenyl)piperazine Property

Boiling point:
100-102°C 0,1mm
Density 
1.226 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.521(lit.)
Flash point:
>230 °F
storage temp. 
-20°C
pka
8.88±0.10(Predicted)
Sensitive 
Air Sensitive
BRN 
614217
CAS DataBase Reference
15532-75-9(CAS DataBase Reference)
NIST Chemistry Reference
Piperazine, 1-[3-(trifluoromethyl)phenyl]-(15532-75-9)
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Safety

Hazard Codes 
Xi,C
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
2735
WGK Germany 
3
RTECS 
TM2820000
Hazard Note 
Corrosive
HazardClass 
8
PackingGroup 
II
HS Code 
29335995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P311Call a POISON CENTER or doctor/physician.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T-920
Product name
3-Trifluoromethylphenylpiperazine (TFMPP)-D4 hydrochloride solution
Purity
100?μg/mLinmethanol(asfreebase),ampuleof1?mL,certifiedreferencemateri
Packaging
1mL
Price
$202
Updated
2024/03/01
SynQuest Laboratories
Product number
3H32-3-41
Product name
1-[(3-Trifluoromethyl)phenyl]piperazine
Purity
99%
Packaging
5G
Price
$15
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-3-41
Product name
1-[(3-Trifluoromethyl)phenyl]piperazine
Purity
99%
Packaging
25g
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-3-41
Product name
1-[(3-Trifluoromethyl)phenyl]piperazine
Purity
99%
Packaging
100g
Price
$145
Updated
2021/12/16
Atlantic Research Chemicals
Product number
XS03856
Product name
1-[3-(Trifluoromethyl)phenyl]piperazine
Purity
95%
Packaging
10gm:
Price
$38.88
Updated
2021/12/16
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N-(3-Trifluoromethylphenyl)piperazine Chemical Properties,Usage,Production

Chemical Properties

clear colourless to yellow slightly viscous liquid

Uses

1-[3-(Trifluoromethyl)phenyl]piperazine is used in preparation of (Piperazinylethyl)cyclohexanamide derivatives and used as treatment or prevention of D3 and/or 5HT-2 receptor diseases.

Definition

ChEBI: A N-arylpiperazine that is piperazine substituted by a 3-(trifluoromethyl)phenyl group at position 1. A serotonergic agonist used as a recreational drug.

Synthesis Reference(s)

Tetrahedron Letters, 37, p. 319, 1996 DOI: 10.1016/0040-4039(95)02162-0

N-(3-Trifluoromethylphenyl)piperazine Preparation Products And Raw materials

Raw materials

Diethylene glycol monomethyl ether Silica gel Hexane Benzyltriethylammonium chloride 2-Diethylaminoethylchloride hydrochloride Diethyl ether Ethyl acetate Bis(2-chloroethyl)amine hydrochloride Methanol Sodium hydroxide 3-Aminobenzotrifluoride Sodium carbonate

Preparation Products

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N-(3-Trifluoromethylphenyl)piperazine Suppliers

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15532-75-9, N-(3-Trifluoromethylphenyl)piperazineRelated Search:

Lithium trifluoromethanesulfonate Benzotrifluoride Trifluoromethanesulfonic acid Diphenyl ether Dichloromethylphenylsilane Methyltriphenylphosphonium bromide 1-Methylpiperazine (Trifluoromethyl)trimethylsilane 1,2-Dimethylhydrazine Dihydrochloride Piperazine 4-Aminobenzotrifluoride 1-BENZHYDRYLPIPERAZINE PHENYL VALERATE PHENYL RESIN 1-(4-CHLORO-3-TRIFLUOROMETHYLPHENYL)PIPERAZINE 1-(3-Trifluoromethylphenyl)piperazine hydrochloride N-(3-Trifluoromethylphenyl)piperazine 1-(4-TRIFLUOROMETHYLPHENYL)PIPERAZINE

  • LABOTEST-BB LT00044462
  • 3-(PIPERAZIN-1-YL)TRIFLUOROMETHYLBENZENE
  • 3-(TRIFLUOROMETHYL)-N-PHENYLPIPERAZINE
  • AKOS BBS-00003586
  • 1-(ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLYL)PIPERAZINE
  • 1-[3-(TRIFLUOROMETHYL)PHENYL]PIPERAZINE
  • 1-(3-TRIFLUOROMETHYL)-PIPERAZINE
  • RARECHEM AH CK 0203
  • N-(ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLYL)PIPERAZINE
  • N-(A,A,A-TRIFLUORO-M-TOLYL)PIPERAZINE
  • N-(3-TRIFLUOROMETHYLPHENYL)PIPERAZINE
  • 1-(α,α,α-Trifluoro-m-tolyl)piperazine
  • 3-(1-Piperazino)benzotrifluoride~N-(alpha,alpha,alpha-Trifluoro-m-tolyl)piperazine
  • N-(alpha,alpha,alpha-trifluoro-3-tolyl)piperazine
  • 3-(1-piperazino)benzotrifluoride
  • n-(à,à,à-trifluoro-m-tolyl)piperazine
  • 1-[3-(Trifluoromethyl)phenyl]piperazine 97%
  • 1-[3-(Trifluoromethyl)phenyl]piperazine97%
  • N-(alpha,alpha,alpha-Trifluoro-m-tolyl)piperazine 1-(3-Trifluoromethyl)phenylpiperazine N-(3-Trifluoromethylphenyl)piperazine
  • 1-(3-Trifloromethyphenyl)piperazin
  • 1-(3-TRIFLUOROMETHYL)PHENYLPIPERAZINE 98+%
  • 1-(A,A,A-TRI-FLUORO-M-TOLYL)-PIPERAZINE
  • Piperazine, 1-[3-(trifluoromethyl)phenyl]-
  • 1-[m-(Trifluoromethyl)phenyl]piperazine
  • TFTP
  • N-(alpha,alpha,alpha-Trifluoro-m-tolyl)piperazine,98%
  • 1-[3-(Trifluoromethyl)phenyl]piperazine ,99%
  • 3-(TRIFLUOROMETHYL)-N-PHENYLPIPERAZINE F
  • 3-TRIFLUOROMETHYLPHENYLPIPERAZINE Hydrochloride D4
  • Flibanserin Impurity 2 Monomer
  • 1-(3-Methoxyphenyl)pipera
  • 15532-75-9
  • AMINE
  • TP - TZ
  • Analytical Chromatography Product Catalog
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  • Piperidines, Piperidones, Piperazines