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2-Diethylaminoethylchloride hydrochloride

Product Name
2-Diethylaminoethylchloride hydrochloride
CAS No.
869-24-9
Chemical Name
2-Diethylaminoethylchloride hydrochloride
Synonyms
DEC;2-Chlorotriethylamine hydrochloride;DEAC HCL;CCMO-39-002;oro-N,N-diethyL;CED 50% Solution;DEAC 65% Solution;TRISMETHOXYBENZENE;3,5-DIMETHOXYANISOLE;2-Diethylaminoethylc
CBNumber
CB3371006
Molecular Formula
C6H15Cl2N
Formula Weight
172.1
MOL File
869-24-9.mol
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2-Diethylaminoethylchloride hydrochloride Property

Melting point:
50-53 °C(lit.)
Boiling point:
255 °C(lit.)
Density 
1.1919 (rough estimate)
vapor pressure 
0Pa at 25℃
refractive index 
1.6000 (estimate)
Flash point:
186 °F
storage temp. 
Poison room
solubility 
methanol: 0.1 g/mL, clear, colorless
form 
Crystalline Powder
color 
White to slightly beige
PH
5 (100g/l, H2O, 20℃)
Water Solubility 
2000 g/L (20 ºC)
Sensitive 
Moisture Sensitive
BRN 
3591991
Stability:
Hygroscopic, Moisture Sensitive
InChIKey
RAGSWDIQBBZLLL-UHFFFAOYSA-N
CAS DataBase Reference
869-24-9(CAS DataBase Reference)
EPA Substance Registry System
Diethyl-(2-chloroethyl)amine hydrochloride (869-24-9)
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Safety

Hazard Codes 
Xn,T,Xi,T+
Risk Statements 
22-36/37/38-26-24/25-23/24/25
Safety Statements 
26-36-45-36/37/39-28A
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
DC2810000
Hazard Note 
Irritant/Very Toxic
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29211980
Hazardous Substances Data
869-24-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H314Causes severe skin burns and eye damage

H341Suspected of causing genetic defects

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D87201
Product name
2-Chloro-N,N-diethylethylamine hydrochloride
Purity
99%
Packaging
1kg
Price
$114
Updated
2024/03/01
Sigma-Aldrich
Product number
1027380
Product name
Amiodarone Related Compound H
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
20mg
Price
$1370
Updated
2022/05/15
Alfa Aesar
Product number
A15107
Product name
2-(Diethylamino)ethyl chloride hydrochloride, 98+%
Packaging
2500g
Price
$234
Updated
2023/06/20
Sigma-Aldrich
Product number
D87201
Product name
2-Chloro-N,N-diethylethylamine hydrochloride
Purity
99%
Packaging
100g
Price
$46.8
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR1646
Product name
Amiodarone Related Compound H
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
200mg
Price
$271
Updated
2022/05/15
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2-Diethylaminoethylchloride hydrochloride Chemical Properties,Usage,Production

Chemical Properties

2-Diethylaminoethylchloride hydrochloride is colourless to beige crystals

Uses

2-Chloro-N,N-diethylethylamine hydrochloride (65% in water) (DEC 65) is used as intermediate for the syntheses of pharmaceuticals (e.g. amiodarone, butetamate citrate, flurazepam and naftidrofuryl). Product Data Sheet

Uses

2-Chloro-N,N-diethylethylamine hydrochloride can be used as an alkylating reagent for the synthesis of:

  • Substituted oxindole derivatives to be used as growth hormone secretagogs.
  • 1-Substituted-5,6-dinitrobenzimidazoles with antimicrobial and antiprotozoal activities.
  • Thiophene containing triarylmethane (TRAM) derivatives to be used as antitubercular agents.
  • Tris(2-(diethylamino)ethyl)amine to be used as a catalyst in combination with CuBr (Et6TREN/CuBr) for atom transfer radical polymerization of n-butyl acrylate.

It can also be used for the derivatization of chitosan to incorporate aminofunctionality onto it at C-6 position.

Uses

2-Diethylaminoethylchloride hydrochloride is used as intermediate for the syntheses of pharmaceuticals (e.g. amiodarone, butetamate citrate, flurazepam and naftidrofuryl). Product Data Sheet

Purification Methods

Crystallise the salt from absolute MeOH (to remove highly coloured impurities). [Beilstein 4 III 240.]

2-Diethylaminoethylchloride hydrochloride Preparation Products And Raw materials

Raw materials

Diethylaminoethanol

Preparation Products

N-(3-Trifluoromethylphenyl)piperazine 1-(2-Methoxyphenyl)piperazine
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2-Diethylaminoethylchloride hydrochloride Suppliers

Global 0

869-24-9, 2-Diethylaminoethylchloride hydrochlorideRelated Search:

4-AMINOAZOBENZENE HYDROCHLORIDE D-Glucosamine hydrochloride Topotecan hydrochloride Ethylenediamine dihydrochloride AMINOGUANIDINE HYDROCHLORIDE N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE 2-(HEXAMETHYLENEIMINO)ETHYL CHLORIDE HYDROCHLORIDE 1-(2-CHLOROETHYL)PYRROLIDINE HYDROCHLORIDE QUINACRINE MUSTARD DIHYDROCHLORIDE TRIS-(2-CHLOROETHYL)-AMINE 1-(2-Chloroethyl)piperidine hydrochloride 2-Diethylaminoethylchloride hydrochloride Difluorochloromethane 1-Chloro-1,1-difluoroethane BETA-DIETHYLAMINOETHYLCHLORIDE HYDROCHLORIDE,DIETHYLAMINOETHYLCHLORIDE HYDROCHLORIDE TRIS(2-CHLOROETHYL)AMINE HYDROCHLORIDE 2-Diisopropylaminoethyl chloride hydrochloride 2-Diethylaminoethanethiol

  • 3,5-DIMETHOXYANISOLE
  • (2-chloroethyl)diethylaminemonohydrochloride
  • 1-chloro-2-(diethylamine)ethanehydrochloride
  • 2-chloroethyl-n,n-diethylaminehydrochloride
  • TRISMETHOXYBENZENE
  • 2-chloro-n,n-diethyl-ethanaminhydrochloride
  • 2-Chlorotriethylaminehydrochl
  • 2-chloro-triethylaminhydrochloride
  • B-(DIETHYLAMINO)ETHYLCHLORIDE HYDROCHLORIDE
  • Ethanamine, 2-chloro-N,N-diethyl-, hydrochloride
  • beta-chloroethyldiethylaminehydrochloride
  • bis(ethyl)-2-chloroethylaminehydrochloride
  • diethyl-beta-chloroethylaminehydrochloride
  • DEC
  • 2-DIETHYLAMINOETHYL CHLORIDE HYDROCHLORIDE (DEAC HCL)
  • DEAC HCL
  • 2-(Diethylamino)ethyl chloride hydrochloride, 98+%
  • N,N-Diethyl-2-chloroethanamine hydrochloride
  • 2-DIETHYLAMINOETHYL CHLORIDE HYDROCHLORIDE extrapure
  • N,N-Diethyl-β-chloroethylamine hydrochloride
  • 2-(Diethylamino)ethyl chloride hydrochloride, 2-Chlorotriethylamine hydrochloride
  • Diethylaminoethylchloride HCI
  • 2-(DITHEYLAMINO)-ETHYL CHLORIDE HCL
  • N-(2-CHLOROETHYL)-N,N-DIETHYLAMINE HYDROCHLORIDE
  • 2-Chloro-N,N-diethylethaneamine hydrochloride
  • 2-Chlorotriethylamine hydrochloride
  • 2-Diethylaminoethylchloride hydrochloride
  • n-(2-chloroethyl)diethylammonium chloride
  • 2-Chloro-N,N-diethylethylamine hydrochloride 98%
  • 2-Chloro-N,N-diethylethylamine hydrochloride (65% in water)
  • 2-Chloroethyldiethylamine·hydrochloric acid
  • 2-Diethylaminoethylchloride hydrochlo
  • Hydrochloride 2-(Diethylamino)ethyl chloride
  • hydrochloride N,N-Diethylaminoethylchloride
  • 2-Diethylaminoethylc
  • 2-(Diethylamino)ethyl chloride hydrochloride, 1-Chloro-2-(diethylamino)ethane hydrochloride
  • n,n-diethyl-2-chloroethylaminehydrochloride
  • n,n-diethyl-beta-chloroethylaminehydrochloride
  • n-2-chloroethyl-n,n-diethylammoniumhydrochloride
  • 2-chloroethyldiethylammonium chloride
  • 2-Diethylaminoethyl chloride HCL (DEAC, HCl)
  • N-(2-Chloroethyl)diethylamine hydrochloride~N-(2-Chloroethyl)diethylammonium chloride
  • CED 50% Solution
  • DEAC 65% Solution
  • N-(2-Chloroethyl)diethylamineHCl
  • 2-DIETHYL AMINE ETHYL CHLORIDE HYDROCHLORIDE
  • 1-CHLORO-2-DIETHYLAMINOETHANE HYDROCHLORIDE
  • 2-Diethylaminoethylchloride hydrochloride, 99.50%
  • 2-DiethylaMinoethylchloride hydrochloride, 99.5%
  • 2-DiethylaMinoethylchloride hydrochloride, 99.5% 250GR
  • 1-DiethylaMino-2-chloroethane Hydrochloride
  • 2-(DiethylaMino)-1-chloroethane Hydrochloride
  • Diethyl(2-chloroethyl)aMine Hydrochloride
  • 2-Chloro-N,N-diethylethylamine Hydrochloride N-(2-Chloroethyl)diethylamine Hydrochloride 2-Chlorotriethylamine Hydrochloride
  • N-(2-CHLOROETHYL)-N,N-DIETHYLAMMONIUM CH
  • Amiodarone Related Compound H (20 mg) (2-chloro-N,N-diethylethanamine hydrochloride)
  • AMiodarone Related CoMpound H
  • EthanaMine,2-chloro-N,N-diethyl-, hydrochloride (1:1)