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ANTI-BCL-X

Product Name
ANTI-BCL-X
Chemical Name
ANTI-BCL-X
Synonyms
BCLX;BCL2L;BCL2L1;PPP1R52;BCL-XL/S;ANTI-BCL-X;Anti-bclxS;Anti-BCL2L1;BCL2 like 1;ANTI-HUMAN BCL-X
CBNumber
CB5439184
Formula Weight
0
MOL File
Mol file
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ANTI-BCL-X Property

storage temp. 
−20°C
form 
buffered aqueous solution
biological source
rabbit
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Safety

WGK Germany 
2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
WH0000598M1
Product name
Monoclonal Anti-BCL2L1 antibody produced in mouse
Purity
clone 3E2-2A5, purified immunoglobulin, buffered aqueous solution
Packaging
100 μg
Price
$541
Updated
2025/07/31
Sigma-Aldrich
Product number
SAB4502623
Product name
Anti-BCL-XL antibody produced in rabbit
Purity
affinity isolated antibody
Packaging
100μG
Price
$522
Updated
2025/07/31
Sigma-Aldrich
Product number
HPA035734
Product name
Anti-BCL2L1 antibody produced in rabbit
Purity
Prestige Antibodies<SUP>&#174;</SUP> Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
Packaging
100 μL
Price
$530
Updated
2025/07/31
Sigma-Aldrich
Product number
AV30475
Product name
Anti-BCL2L1 antibody produced in rabbit
Purity
IgG fraction of antiserum
Packaging
100 μL
Price
$457
Updated
2025/07/31
Sigma-Aldrich
Product number
AV02008
Product name
Anti-BCL2L1 antibody produced in rabbit
Purity
affinity isolated antibody
Packaging
100μL
Price
$493
Updated
2025/07/31
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ANTI-BCL-X Chemical Properties,Usage,Production

Uses

Useful for the study of apoptosis, screening inhibitors, and selectivity profiling.

Biological Activity

BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators th at are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.

ANTI-BCL-X Preparation Products And Raw materials

Raw materials

Preparation Products

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ANTI-BCL-X Suppliers

SIGMA-RBI
Tel
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Fax
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Country
Switzerland
ProdList
6896
Advantage
91

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