GALANTHAMINE HYDROBROMIDE
- Product Name
- GALANTHAMINE HYDROBROMIDE
- CAS No.
- 69353-21-5
- Chemical Name
- GALANTHAMINE HYDROBROMIDE
- Synonyms
- NIVALIN;1990/4/4;nivaline;NIVALIN, HBR;zocin-6-olhbr;GALANTAMINE HBR;GALANTHAMINE HBR;jilkonhydrobromide;Galantamine N-D3 HBr;Galantamine O-D3 HBr
- CBNumber
- CB5439816
- Molecular Formula
- C17H22BrNO3
- Formula Weight
- 368.27
- MOL File
- 69353-21-5.mol
GALANTHAMINE HYDROBROMIDE Property
- storage temp.
- Sealed in dry,Room Temperature
- form
- White solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 345670
- Product name
- Galanthamine, Hydrobromide
- Purity
- A competitive and reversible inhibitor of acetylcholinesterase.
- Packaging
- 20mg
- Price
- $159
- Updated
- 2024/03/01
- Product number
- INB0000936
- Product name
- (-)-GALANTHAMINE HYDROBROMIDE
- Purity
- 95.00%
- Packaging
- 2MG
- Price
- $577.38
- Updated
- 2021/12/16
- Product number
- INB0000936
- Product name
- (-)-GALANTHAMINE HYDROBROMIDE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $748.87
- Updated
- 2021/12/16
- Product number
- CD31001044
- Product name
- Galantamine Hydrobromide
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $170
- Updated
- 2021/12/16
- Product number
- CD31001044
- Product name
- Galantamine Hydrobromide
- Purity
- 95+%
- Packaging
- 1g
- Price
- $426
- Updated
- 2021/12/16
GALANTHAMINE HYDROBROMIDE Chemical Properties,Usage,Production
General Description
A competitive and reversible inhibitor of acetylcholinesterase. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats. Reported to improve learning and short-term memory in animal models.
Biochem/physiol Actions
Primary TargetAcetylcholinesterase
Clinical Use
Galantamine, which was introduced in 2001, is an alkaloid found in plants of the family Amaryllidaceae, which includes the daffodil (Narcissus pseudonarcissus) and snowflake (Leucojum aestivum). It is a reversible inhibitor of AChE, but it does not appear to inhibit butyrylcholinesterase. Because it is a tertiary amine and can cross the blood-brain barrier, it is indicated for treatment of mild-to-moderate AD and dementia. It has been used outside the U.S. for more than 30 years as an anticurare agent in anesthesia. Galantamine differs from other cholinesterase inhibitors, because it allosterically binds to nicotinic receptors, giving it a dual cholinergic action.
Metabolism
It is metabolized (75%) by CYP2D6 and CYP3A4 to afford the normethyl, O-desmethyl, and O-desmethylnormethyl metabolites, along with some other minor metabolites. Unlike tacrine, galantamine is not associated with hepatotoxicity. Its elimination half-life is 5.7 hours.
GALANTHAMINE HYDROBROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
GALANTHAMINE HYDROBROMIDE Suppliers
View Lastest Price from GALANTHAMINE HYDROBROMIDE manufacturers
- Product
- Galantamine Hydrobromide 69353-21-5
- Price
- US $1.00-1900.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2023-04-11
- Product
- Galantamine hydrobromide 69353-21-5
- Price
- US $100.00/kg
- Min. Order
- 1kg
- Purity
- >99%
- Supply Ability
- 20tons
- Release date
- 2023-10-12
- Product
- Galantamine Hydrobromide 69353-21-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 50000KG/month
- Release date
- 2024-04-12