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GALANTHAMINE HYDROBROMIDE

Product Name
GALANTHAMINE HYDROBROMIDE
CAS No.
69353-21-5
Chemical Name
GALANTHAMINE HYDROBROMIDE
Synonyms
NIVALIN;1990/4/4;nivaline;NIVALIN, HBR;zocin-6-olhbr;GALANTAMINE HBR;GALANTHAMINE HBR;jilkonhydrobromide;Galantamine N-D3 HBr;Galantamine O-D3 HBr
CBNumber
CB5439816
Molecular Formula
C17H22BrNO3
Formula Weight
368.27
MOL File
69353-21-5.mol
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GALANTHAMINE HYDROBROMIDE Property

storage temp. 
Sealed in dry,Room Temperature
form 
White solid
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
DF8075000
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
345670
Product name
Galanthamine, Hydrobromide
Purity
A competitive and reversible inhibitor of acetylcholinesterase.
Packaging
20mg
Price
$159
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
INB0000936
Product name
(-)-GALANTHAMINE HYDROBROMIDE
Purity
95.00%
Packaging
2MG
Price
$577.38
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000936
Product name
(-)-GALANTHAMINE HYDROBROMIDE
Purity
95.00%
Packaging
10MG
Price
$748.87
Updated
2021/12/16
Crysdot
Product number
CD31001044
Product name
Galantamine Hydrobromide
Purity
95+%
Packaging
250mg
Price
$170
Updated
2021/12/16
Crysdot
Product number
CD31001044
Product name
Galantamine Hydrobromide
Purity
95+%
Packaging
1g
Price
$426
Updated
2021/12/16
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GALANTHAMINE HYDROBROMIDE Chemical Properties,Usage,Production

General Description

A competitive and reversible inhibitor of acetylcholinesterase. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats. Reported to improve learning and short-term memory in animal models.

Biochem/physiol Actions

Primary TargetAcetylcholinesterase

Clinical Use

Galantamine, which was introduced in 2001, is an alkaloid found in plants of the family Amaryllidaceae, which includes the daffodil (Narcissus pseudonarcissus) and snowflake (Leucojum aestivum). It is a reversible inhibitor of AChE, but it does not appear to inhibit butyrylcholinesterase. Because it is a tertiary amine and can cross the blood-brain barrier, it is indicated for treatment of mild-to-moderate AD and dementia. It has been used outside the U.S. for more than 30 years as an anticurare agent in anesthesia. Galantamine differs from other cholinesterase inhibitors, because it allosterically binds to nicotinic receptors, giving it a dual cholinergic action.

Metabolism

It is metabolized (75%) by CYP2D6 and CYP3A4 to afford the normethyl, O-desmethyl, and O-desmethylnormethyl metabolites, along with some other minor metabolites. Unlike tacrine, galantamine is not associated with hepatotoxicity. Its elimination half-life is 5.7 hours.

GALANTHAMINE HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from GALANTHAMINE HYDROBROMIDE manufacturers

Wuhan Cell Pharmaceutical Co., Ltd
Product
Galantamine Hydrobromide 69353-21-5
Price
US $1.00-1900.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2023-04-11
Hong Kong Excellence Biotechnology Co., Ltd.
Product
Galantamine hydrobromide 69353-21-5
Price
US $100.00/kg
Min. Order
1kg
Purity
>99%
Supply Ability
20tons
Release date
2023-10-12
Shanghai Affida new material science and technology center
Product
Galantamine Hydrobromide 69353-21-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99
Supply Ability
50000KG/month
Release date
2024-04-12

69353-21-5, GALANTHAMINE HYDROBROMIDERelated Search:


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  • 5-Methoxy-9-methyl-2,3,3a,3a1,8,9,10,11-octahydro-4-oxa-9-azacycloocta[def]fluoren-2-ol hydrobromide
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  • 69353-21-5
  • 1953-4-4
  • C17H21NO3BrH
  • Alkaloids
  • Alkaloids (Others)
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors
  • Cholinesterase
  • A to C
  • BioChemical
  • Biochemicals and Reagents
  • Galantamine