ChemicalBook > CAS DataBase List > H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH

H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH

Product Name
H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
CAS No.
123562-20-9
Chemical Name
H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
Synonyms
ET-2 (HUMAN);ENDOTHELIN 2;ENDOTHELIN 2 HUMAN;Human endothelin-2;ENDOTHELIN-II, HUMAN;Endothelin-2 (49-69);ET-2 (HUMAN, PIG, DOG);EDOTHELIN 2 HUMAN 50 UG;Endothelin 2 (huMan)(9CI);Endothelin-2 (49-69), human
CBNumber
CB5442638
Molecular Formula
C115H160N26O32S4
Formula Weight
2546.92
MOL File
123562-20-9.mol
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H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Property

Density 
1.286±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
storage temp. 
−20°C
solubility 
Soluble to 1 mg/ml in DMSO
form 
powder
color 
white
Water Solubility 
Soluble in water (1 mg/ml)
Sequence
Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
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Safety

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
28-36/37-45
RIDADR 
UN 2811 6.1/PG 1
WGK Germany 
3
F 
3-10
HazardClass 
6.1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H300Fatal if swallowed

H310Fatal in contact with skin

H330Fatal if inhaled

Precautionary statements

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P320Specific treatment is urgent (see … on this label).

P330Rinse mouth.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E9012
Product name
Endothelin-2, human
Purity
≥97%(HPLC),powder
Packaging
50μg
Price
$388.55
Updated
2025/07/31
Sigma-Aldrich
Product number
E9012
Product name
Endothelin-2, human
Purity
≥97%(HPLC),powder
Packaging
0.1mg
Price
$685.9
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
PEP0001286
Product name
ENDOTHELIN 2, HUMAN
Purity
95.00%
Packaging
0.5MG
Price
$952.88
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0001286
Product name
ENDOTHELIN 2, HUMAN
Purity
95.00%
Packaging
1MG
Price
$1341.3
Updated
2021/12/16
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H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Chemical Properties,Usage,Production

Uses

Endothelin-2 (49-69), human (Endothelin-2 (human, canine)) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.

in vivo

Two distinct phases of pressor effects are typically seen in response to Endothelin-2: the early phase immediately follows the depressor response and dominates during the next 3-10 min, whereas the late pressor effect develops 10-20 min after the injection and lasts >1 hr[1].

storage

-20°C (desiccate)

References

[1] Grimshaw MJ, et al. Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors. Eur J Immunol. 2002 Sep;32(9):2393-400. DOI:10.1002/1521-4141(200209)32:93.0.CO;2-4

H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Suppliers

China 86 France 1 Germany 4 Japan 3 Switzerland 2 United Kingdom 2 United States 17 USA 1 Global 116
3B Pharmachem (Wuhan) International Co.,Ltd.
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Creative Peptides
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View Lastest Price from H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH manufacturers

Career Henan Chemical Co
Product
H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH 123562-20-9
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-13
Career Henan Chemical Co
Product
H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH 123562-20-9
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-13

123562-20-9, H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OHRelated Search:

Endothelin-1 (human, porcine) NITRIC OXIDE H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH BIG ET-1 (1-38) (HUMAN) IRL-1038 ENDOTHELIN (16-21) Serotonin hydrochloride HISTONE L(+)-Arginine Follicle stimulating hormone Histamine Luteinizing Hormone Prostaglandin E2 RENNIN Bilirubin Bacterial endotoxin Endothelin antagonist H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH

  • ET-2 (HUMAN)
  • ET-2 (HUMAN, PIG, DOG)
  • H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
  • H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH (DISULFIDE BRIDGE: 1-15 AND 3-11)
  • ENDOTHELIN-II, HUMAN
  • ENDOTHELIN 2
  • ENDOTHELIN 2 HUMAN
  • ENDOTHELIN-2 (HUMAN, CANINE)
  • ENDOTHELIN-2 (HUMAN, PIG, DOG)
  • CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP
  • CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP HUMAN
  • CSCSSWLDKECVYFCHLDIIW (DISULFIDE BRIDGE: 1-15 AND 3-11)
  • EDOTHELIN 2 HUMAN 50 UG
  • CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR- PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP(DISULFIDE BRIDGE:CYS1-CYS15, CYS3-CYS11)
  • CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP: CSCSSWLDKECVYFCHLDIIW DISULFIDE BRIDGES CYS1-CYS15, CYS3-CYS11
  • Endothelin-2 (huMan, canine) ET-2 (huMan, canine), VIC (huMan, canine)
  • Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridges Cys1-Cys15 and Cys3-Cys11)
  • ET-2 (huMan, canine), VIC (huMan, canine)
  • M.W. 2546.92 C115H160N26O32S4
  • Endothelin 2, huManEndotheli
  • Endothelin 2 (Canis familiaris)
  • Human endothelin-2
  • Endothelin 2 (huMan)(9CI)
  • Endothelin 2, human, ≥97.0% (HPLC)
  • Endothelin 1 (swine), 6-L-tryptophan-7-L-leucine-
  • H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH USP/EP/BP
  • Endothelin-2 (49-69), human
  • Endothelin-2 (49-69)
  • peptide,21-amino,inhibit,Human endothelin 2,vasoactive,acid,ET-RB,Endothelin 2 (49 69), human,Endothelin2 (4969), human,Human endothelin2,ET-RA,Inhibitor,transmembrane
  • Endothelin-2 (human, canine) acetate
  • Endothelin-2 (human, canine) trifluoroacetate
  • 123562-20-9
  • C115H160N26O32S4
  • Endothelins
  • Peptides
  • Amino Acids and Peptides
  • Biochemicals and Reagents
  • BioChemical
  • Agonist
  • Cardiovescular
  • Peptide
  • AgonistsApplication Index
  • Chymase and Related Products
  • Cell Signaling Enzymes
  • Endothelins
  • Peptides for Cell Biology
  • Endothelin receptor