4-HYDROXY-6-IODOQUINOLINE
- Product Name
- 4-HYDROXY-6-IODOQUINOLINE
- CAS No.
- 342617-07-6
- Chemical Name
- 4-HYDROXY-6-IODOQUINOLINE
- Synonyms
- BUTTPARK 100\01-54;6-Iodo-4-quinolinol;6-IODOQUINOLIN-4-OL;4-Quinolinol, 6-iodo-;6-iodo-1H-quinolin-4-one;6-IODOQUINOLIN-4(1H)-ONE;4-HYDROXY-6-IODOQUINOLINE;4-Hyrdroxy-6-iodoquinoline
- CBNumber
- CB5447961
- Molecular Formula
- C9H6INO
- Formula Weight
- 271.05
- MOL File
- 342617-07-6.mol
4-HYDROXY-6-IODOQUINOLINE Property
- Boiling point:
- 394℃
- Density
- 1.974
- Flash point:
- 192℃
- storage temp.
- 2-8°C(protect from light)
- pka
- 3.85±0.40(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- I737140
- Product name
- 6-Iodoquinolin-4-ol
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 279808
- Product name
- 4-Hyrdroxy-6-iodoquinoline
- Packaging
- 1g
- Price
- $432
- Updated
- 2021/12/16
- Product number
- 126409
- Product name
- 4-Hydroxy-6-iodoquinoline
- Purity
- >95%
- Packaging
- 25g
- Price
- $845
- Updated
- 2021/12/16
- Product number
- HCH0055254
- Product name
- 4-HYDROXY-6-IODOQUINOLINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $852.55
- Updated
- 2021/12/16
- Product number
- HCH0055254
- Product name
- 4-HYDROXY-6-IODOQUINOLINE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1227.82
- Updated
- 2021/12/16
4-HYDROXY-6-IODOQUINOLINE Chemical Properties,Usage,Production
Synthesis
909344-69-0
342617-07-6
The reaction was carried out by batchwise addition of 5-{[(4-iodophenyl)amino]methylene}-2,2-dimethyl-1,3-dioxane-4,6-dione (120 g) in diphenyl ether (1.3 L, 8.0 mol) at 240 °C for 1.5 hours. After completion of the reaction, the mixture was cooled to room temperature and poured into 1.5 L of hexane. The resulting suspension was filtered and the filter cake was broken and washed with hexane (2 x 500 mL). The solid was dried under vacuum to afford 6-iodo-4-hydroxyquinoline as a brown solid (80 g, 82% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ11.89 (d, J=4.0 Hz, 1H), 8.36 (d, J=2.3 Hz, 1H), 7.89-7.98 (m, 2H), 7.37 (d, J=8.6 Hz, 1H), 6.07 (dd, J=7.5,1.1 Hz, 1H); mass spectra (m /z) 272.0 (M+H+).
References
[1] Patent: US2012/41024, 2012, A1. Location in patent: Page/Page column 8; 10; 16
[2] Patent: EP2566477, 2015, B1. Location in patent: Paragraph 0157; 0159
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 10, p. 4867 - 4880
4-HYDROXY-6-IODOQUINOLINE Preparation Products And Raw materials
Raw materials
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View Lastest Price from 4-HYDROXY-6-IODOQUINOLINE manufacturers
- Product
- 4-HYDROXY-6-IODOQUINOLINE 342617-07-6
- Price
- US $1.00/KG
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-10