2,6-Dichlorobenzoxazole
- Product Name
- 2,6-Dichlorobenzoxazole
- CAS No.
- 3621-82-7
- Chemical Name
- 2,6-Dichlorobenzoxazole
- Synonyms
- DCBO;N-Butyldiolamine;dichlorobenzoxazole;2,6-chlorobenzoxazole;6-Dichlorobenzoxazole;2,6-Dichlorbenzoxazol;2,6-DICHLOROBENZOXAZOLE;2,6-Dichlorobenzoxazolel;2,6-Dichlorobenzoxazole>2,6-dichlorobenzo[d]oxazole
- CBNumber
- CB5452404
- Molecular Formula
- C7H3Cl2NO
- Formula Weight
- 188.01
- MOL File
- 3621-82-7.mol
2,6-Dichlorobenzoxazole Property
- Melting point:
- 49-51°C
- Boiling point:
- 110°C/13mmHg(lit.)
- Density
- 1.522±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -0.96±0.30(Predicted)
- form
- fused solid
- color
- White
- InChI
- InChI=1S/C7H3Cl2NO/c8-4-1-2-5-6(3-4)11-7(9)10-5/h1-3H
- InChIKey
- LVVQTPZQNHQLOM-UHFFFAOYSA-N
- SMILES
- O1C2=CC(Cl)=CC=C2N=C1Cl
- CAS DataBase Reference
- 3621-82-7(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- D3459
- Product name
- 2,6-Dichlorobenzoxazole
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $22
- Updated
- 2021/12/16
- Product number
- D3459
- Product name
- 2,6-Dichlorobenzoxazole
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $63
- Updated
- 2021/12/16
- Product number
- D432090
- Product name
- 2,6-Dichlorobenzoxazole
- Packaging
- 5g
- Price
- $140
- Updated
- 2021/12/16
- Product number
- 44414
- Product name
- 2,6-Dichlorobenzoxazole,≥98%(GC)
- Purity
- ≥98%(GC)
- Packaging
- 5G
- Price
- $25.7
- Updated
- 2021/12/16
- Product number
- 4H56-5-K5
- Product name
- 2,6-Dichloro-1,3-benzoxazole
- Purity
- 98.0%
- Packaging
- 25g
- Price
- $53
- Updated
- 2021/12/16
2,6-Dichlorobenzoxazole Chemical Properties,Usage,Production
Chemical Properties
This product is solid, insoluble in water, soluble in chlorobenzene.
Uses
2,6-Dichlorobenzoxazole is used in the synthesis of 2-(3-(2,6-dichloro-4-(3,3-dichloroallyloxy)phenoxy)propoxy)-5-(trifluoromethyl)benzo[d]oxazole, an insecticide against Spodoptera exigua.
Synthesis
22876-20-6
3621-82-7
General procedure for the synthesis of 2,6-dichlorobenzoxazole from 6-chlorobenzo[d]oxazole-2(3H)-thione: In a 500-mL four-neck reaction flask, 50 g (0.27 mol) of 6-chlorobenzo[d]oxazole-2(3H)-thione, 300 mL of toluene, and 40 g (0.135 mol) of tris(trichloromethyl)carbonate were added. The reaction mixture was slowly warmed to 50°C and the temperature was continued at a rate of 0.5°C/min, holding the temperature for 10 minutes after each 10°C increase. When the temperature reached 105°C, the reaction was maintained for 1 hour. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure (the initial vacuum was maintained at -0.07 MPa, and when the temperature was raised to 100°C-110°C, the vacuum was increased to -0.095 MPa to completely evaporate the solvent). After evaporation, the residue was removed while hot and cooled and crystallized to give 50.82 g of 2,6-dichlorobenzoxazole with a product purity of 98.1% and a molar yield of 98.4%.
References
[1] Patent: CN102432559, 2016, B. Location in patent: Paragraph 0020; 0037; 0038
[2] Patent: WO2018/37223, 2018, A1. Location in patent: Page/Page column 197; 198
[3] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 7, p. 1975 - 1980
[4] Journal of Organic Chemistry, 2009, vol. 74, # 8, p. 3229 - 3231
[5] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 9, p. 3044 - 3049
2,6-Dichlorobenzoxazole Preparation Products And Raw materials
Raw materials
Preparation Products
2,6-Dichlorobenzoxazole Suppliers
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- Fax
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- chemcontrol@nextra.sk
- Country
- Slovakia
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View Lastest Price from 2,6-Dichlorobenzoxazole manufacturers
- Product
- 2,6-Dichlorobenzoxazole 3621-82-7
- Price
- US $8.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-28
- Product
- 2,6-Dichlorobenzoxazole 3621-82-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-22
- Product
- 2,6-Dichlorobenzoxazole 3621-82-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20t
- Release date
- 2024-07-15