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5-Heptylresorcinol

Product Name
5-Heptylresorcinol
CAS No.
500-67-4
Chemical Name
5-Heptylresorcinol
Synonyms
SPHEROPHORAL;5-Heptylbenzene-1,3-diol;spherophorol;5-Heptyl-1,3-benzenediol;5-HEPTYLRESORCINOL;7-methylheptanoicacid;5-HEPTYLRESORCINOL 95%;3,5-Dihydroxyheptylbenzene;1,3-Benzenediol, 5-heptyl-
CBNumber
CB5456174
Molecular Formula
C13H20O2
Formula Weight
208.3
MOL File
500-67-4.mol
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5-Heptylresorcinol Property

Melting point:
55-57°C
Boiling point:
342.3±12.0 °C(Predicted)
Density 
1.033±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator, under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.57±0.10(Predicted)
color 
White to Off-White
InChI
InChI=1S/C13H20O2/c1-2-3-4-5-6-7-11-8-12(14)10-13(15)9-11/h8-10,14-15H,2-7H2,1H3
InChIKey
QENPJKGENOZEEJ-UHFFFAOYSA-N
SMILES
C1(O)=CC(CCCCCCC)=CC(O)=C1
NIST Chemistry Reference
5-Heptylresorcinol(500-67-4)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
H267500
Product name
5-Heptylresorcinol
Packaging
10mg
Price
$100
Updated
2021/12/16
TRC
Product number
H267500
Product name
5-Heptylresorcinol
Packaging
1g
Price
$2665
Updated
2021/12/16
Chemenu
Product number
CM328669
Product name
5-heptylbenzene-1,3-diol
Purity
95%+
Packaging
1000g
Price
$17280
Updated
2021/12/16
AHH
Product number
MT-14529
Product name
5-Heptylresorcinol
Purity
95%
Packaging
5g
Price
$735
Updated
2021/12/16
Chemenu
Product number
CM328669
Product name
5-heptylbenzene-1,3-diol
Purity
95%+
Packaging
10g
Price
$1012
Updated
2021/12/16
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5-Heptylresorcinol Chemical Properties,Usage,Production

Uses

5-Heptylresorcinol and other alkylhydroxybenzenes have been used to study the protective effect in Saccharomyces cerevisiae against oxidative and radiation-caused damage.

Definition

5-Heptylresorcinol is one of the main volatile compounds present in F. japonicum stem oils (6.5%) which presented apparent antioxidant and antibacterial capacities[1]. It is a cannabinoid compound related to the structure of cannabinoids, which has been shown to have cannabinoid effects in animals and humans.

Biological Activity

5-Heptylresorcinol binds to CB1 receptor with high strength and selectivity, and has been shown to induce low metabolism in mice by selectively binding CB1 at large doses

Synthesis

To a solution of 1-heptyl-3,5-dimethoxy-Benzene (388 mg, 1.41 mmol) in dry CH2Cl2 (47 mL) at -78 °C under an argon atmosphere was added boron tribromide (3.4 mL, 1 M solution in CH2Cl2). Following this addition, the reaction temperature was gradually raised over a period of 3 h to 0 °C, and the stirring continued at that temperature until the reaction was completed (28 h). Unreacted boron tribromide was destroyed by adding methanol at -78 °C. The resulting mixture was warmed at room temperature and stirred for 40 min, and the volatiles were removed in vacuo. The residue was diluted with EtOAc and washed with saturated NaHCO3 solution, water, and brine. The organic layer was dried over Na2SO4, filtered, and concentrated under reduced pressure. Purification by flash column chromatography (45% diethyl etherpetroleum ether) afforded 340 mg (97% yield) of the compound as a slightly brown viscous oil: 5-Heptylresorcinol (. The synthesis was carried out as described for 5-Heptylresorcinol by using 15 (1.18 g, 5 mmol) and boron tribromide (11 mL, 11 mmol, 1 M solution in CH2Cl2) in anhydrous CH2Cl2 (40 mL): yield 91% (0.95 g); slightly brown solid; mp 53-54 °C (lit.63 mp 55-56 °C); spectral and analytical data were reported previously.

References

[1] Wei Q R, et al. Composition and Antioxidative and Antibacterial Activities of the Essential Oil from Farfugium japonicum. Molecules, 2023; 28: 2774.

5-Heptylresorcinol Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Heptylresorcinol Suppliers

Xiamen Work-For-World Medcine Co., Ltd
Tel
15921822462; 15921822462
Email
keqingyong@wfwmed.com
Country
China
ProdList
122
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58
Taizhou Blazer Biomedical Technology Co., Ltd.
Tel
0523-86112008 13915404123
Fax
0523-86112008
Email
sales@blazerbio.com
Country
China
ProdList
299
Advantage
58
Nataorganic material (suzhou) Co., Ltd.
Tel
13555462360
Email
luojx@natachem.com
Country
China
ProdList
235
Advantage
58
Shanghai Arbor Chemical Co., Ltd.
Tel
021-60451682 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
856
Advantage
55
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16684
Advantage
50
BEIJING EAGLE SKY PHARMATECH CO., LTD
Tel
010-88755821 13911359480
Email
sophia_818@126.com
Country
China
ProdList
305
Advantage
55
DebyeTec.com Inc.
Tel
18086626237 18086626237
Fax
qq:2693528373
Email
sales@debyesci.com
Country
China
ProdList
2645
Advantage
56
INTERCHEMIE NANJING PHARMATECH CO., LTD
Tel
13656237714 13656237714
Fax
0512-65852853
Email
xiaokunfu@kyyykj.com
Country
China
ProdList
295
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
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View Lastest Price from 5-Heptylresorcinol manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
5-Heptylresorcinol 500-67-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-15
Shandong Deshang Chemical Co., Ltd.
Product
5-Heptylresorcinol 500-67-4
Price
US $5.90-3.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 tons
Release date
2024-06-26
Hebei Yanxi Chemical Co., Ltd.
Product
5-heptylbenzene-1,3-diol 500-67-4
Price
US $40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-09-21

500-67-4, 5-HeptylresorcinolRelated Search:


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  • 5-Heptyl-1,3-benzenediol
  • 5-HEPTYLRESORCINOL
  • 5-Heptylbenzene-1,3-diol
  • 5-HEPTYLRESORCINOL 95%
  • spherophorol
  • 3,5-Dihydroxyheptylbenzene
  • 7-methylheptanoicacid
  • 500-67-4
  • HO2C6H3CH26CH3