ChemicalBook > CAS DataBase List > 3,5-Dibromo-2-hydroxypyrazine

3,5-Dibromo-2-hydroxypyrazine

Product Name: 3,5-Dibromo-2-hydroxypyrazine
CAS No.: 21943-15-7
Chemical Name: 3,5-Dibromo-2-hydroxypyrazine
Synonyms: 3,5-bromopyrazin-2-ol;3,5-DIBROMO-PYRAZIN-2-OL;3,5-dibromo-2(1H)-Pyrazinone;3,5-dibromo-1H-pyrazin-2-one;3,5-DIBROMO-2-HYDROXYPYRAZINE;2-Hydroxy-3,5-dibromopyrazine;2(1H)-Pyrazinone, 3,5-dibromo-;3,5-DibroMo-2-hydroxypyrazine, 95+%;3,5-Dibromo-2-hydroxypyrazine ISO 9001：2015 REACH
CBNumber: CB5460276
Molecular Formula: C4H2Br2N2O
Formula Weight: 253.88
MOL File: 21943-15-7.mol

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3,5-Dibromo-2-hydroxypyrazine Property

Melting point:: 174-178°C
Density: 2.53±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 8.35±0.60(Predicted)
Appearance: Light yellow to yellow Solid
InChI: InChI=1S/C4H2Br2N2O/c5-2-1-7-4(9)3(6)8-2/h1H,(H,7,9)
InChIKey: NHVGHXUOFWEOSN-UHFFFAOYSA-N
SMILES: C1(=O)NC=C(Br)N=C1Br

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
Safety Statements: 26-39
WGK Germany: 1
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D425525
Product name: 3,5-Dibromo-2-pyrazinone
Packaging: 25g
Price: $825
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD139570
Product name: 3,5-Dibromopyrazin-2-ol
Packaging: 50g
Price: $891
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0029430
Product name: 3,5-DIBROMO-2-HYDROXYPYRAZINE
Purity: 95.00%
Packaging: 5G
Price: $1302.84
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD139570
Product name: 3,5-Dibromopyrazin-2-ol
Packaging: 25g
Price: $524
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0029430
Product name: 3,5-DIBROMO-2-HYDROXYPYRAZINE
Purity: 95.00%
Packaging: 1G
Price: $743.82
Updated: 2021/12/16

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3,5-Dibromo-2-hydroxypyrazine Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

3,5-Dibromo-pyrazinol ,is a pyrazine derivative that can be used as a potential building block in chemical synthesis. It can also be used in SRN1 mechanism in heteroaromatic nucleophilic substitution.

Synthesis

24241-18-7

21943-15-7

Preparation of compound 36a: 3,5-dibromopyrazin-2-ol To a stirred solution of 3,5-dibromopyrazin-2-amine (30 g, 0.12 mol) in acetic acid (300 mL) was added sulfuric acid (50 mL) dropwise at 15-25 °C. Subsequently, a solution of sodium nitrite (16.6 g, 0.24 mol) in water (100 mL) was added dropwise to the resulting solution over a period of 1.5 hours at 10-15°C. After the dropwise addition was completed, the reaction mixture was continued to be stirred at 10-15 °C for 1 hour. The reaction mixture was poured into water (3L) and extracted with ethyl acetate (1L x 3). The organic layers were combined, washed sequentially with saturated sodium bicarbonate solution (1L×3) and brine (1L), dried with anhydrous sodium sulfate, and concentrated under reduced pressure to afford 3,5-dibromo-2-hydroxypyrazine (36a) as a yellow solid (24 g, 79.4% yield). 1H NMR (400 MHz, CDCl3): δ 7.44 (s, 1H).

References

[1] Patent: WO2010/16005, 2010, A1. Location in patent: Page/Page column 144

3,5-Dibromo-2-hydroxypyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3,5-Dibromo-2-hydroxypyrazine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3,5-Dibromo-2-hydroxypyrazine 21943-15-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 800 tons
Release date: 2020-04-28

Career Henan Chemical Co

Product: 3,5-Dibromo-2-hydroxypyrazine 21943-15-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-01

21943-15-7, 3,5-Dibromo-2-hydroxypyrazineRelated Search:

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3,5-DibroMo-2-hydroxypyrazine, 95+%

3,5-dibromo-1H-pyrazin-2-one

3,5-DIBROMO-2-HYDROXYPYRAZINE

3,5-DIBROMO-PYRAZIN-2-OL

3,5-bromopyrazin-2-ol

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3,5-Dibromo-2-hydroxypyrazine ISO 9001：2015 REACH

21943-15-7

C4H2Br2N2O