LOSARTAN-D4
- Product Name
- LOSARTAN-D4
- CAS No.
- 1030937-27-9
- Chemical Name
- LOSARTAN-D4
- Synonyms
- MK-954-d4;Cozaar-d4;DuP-753 D4;LOSARTAN-D4;D4-Losartan;[2H4]-Losartan;Reaxys ID: 18951469;Losartan-d4 in methanol;2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5yl)[1,1'-biphenyl-d4]-4-yl]Methyl]-1H-iMidazole-5-Methanol;(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl
- CBNumber
- CB5465064
- Molecular Formula
- C22H19ClD4N6O
- Formula Weight
- 426.94
- MOL File
- Mol file
LOSARTAN-D4 Property
- Melting point:
- 184-190C
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- Chloroform (Slightly),Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H228Flammable solid
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
N-Bromosuccinimide Price
- Product number
- 22567
- Product name
- Losartan-d4
- Purity
- ≥99% deuterated forms (d1-d4)
- Packaging
- 500μg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 22567
- Product name
- Losartan-d4
- Purity
- ≥99% deuterated forms (d1-d4)
- Packaging
- 1mg
- Price
- $230
- Updated
- 2024/03/01
- Product number
- L470503
- Product name
- Losartan-d4
- Packaging
- 25mg
- Price
- $2025
- Updated
- 2021/12/16
- Product number
- 015677
- Product name
- Losartan-d4
- Packaging
- 1mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- BICR171
- Product name
- Losartan-D4
- Packaging
- 5mg
- Price
- $493
- Updated
- 2021/12/16
LOSARTAN-D4 Chemical Properties,Usage,Production
Description
Losartan-D4 is a deuterium-labeled version of Losartan, which is an angiotensin II receptor antagonist that competes with the binding of angiotensin II to AT1 receptors with an IC50 of 20 nM. Losartan is an antagonist of the angiotensin (AT) II receptor subtype AT1 with a K i value of 5-20 nM.
Chemical Properties
White Solid
Uses
A labelled version of Losartan, a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
Uses
As a labelled version of Losartan, Losartan-d4 can be used as a nonpeptide angiotensin II AT1-receptor antagonist and Antihypertensive.
Uses
Losartan-d4 can be intended for use as an internal standard for the quantification of Losartan by GC- or LC-mass spectrometry.
IC 50
AT1 Receptor
LOSARTAN-D4 Preparation Products And Raw materials
Raw materials
Preparation Products
LOSARTAN-D4 Suppliers
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