Megestrol

ChemicalBook > CAS DataBase List > Megestrol

Product Name: Megestrol
CAS No.: 3562-63-8
Chemical Name: Megestrol
Synonyms: C07120;Megestro;MEGESTROL;Megestrol USP/EP/BP;Megestrol in Methanol;megestrol solution,100ppm;Megestrol acetate EP Impurity B;Megestrol 100 μg/ml Acetonitrile;Metesterone acetate EP impurity B;4,6-PREGNADIEN-6-METHYL-17-OL-3,20-DIONE
CBNumber: CB5465978
Molecular Formula: C22H30O3
Formula Weight: 342.47
MOL File: 3562-63-8.mol

Less

Megestrol Property

Melting point:: 207-208 °C(Solv: ethyl ether (60-29-7); acetone (67-64-1))
Boiling point:: 500.4±50.0 °C(Predicted)
Density: 1.15±0.1 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 13.00±0.70(Predicted)
color: White to Off-White
CAS DataBase Reference: 3562-63-8(CAS DataBase Reference)

Less

Safety

Hazardous Substances Data: 3562-63-8(Hazardous Substances Data)

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

TRC

Product number: M208040
Product name: Megestrol
Packaging: 50mg
Price: $145
Updated: 2021/12/16

Usbiological

Product number: M2860-55B
Product name: Megestrol
Packaging: 500ul
Price: $306
Updated: 2021/12/16

TRC

Product number: M208040
Product name: Megestrol
Packaging: 500mg
Price: $1165
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0006501
Product name: MEGESTROL
Purity: 95.00%
Packaging: 500MG
Price: $1686.3
Updated: 2021/12/16

ChemScene

Product number: CS-0013903
Product name: Megestrol
Purity: 99.69%
Packaging: 100mg
Price: $200
Updated: 2021/12/16

Less

Megestrol Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Megestrol is an orally active progestogen. Megestrol is used in combinations as oral contraceptive and as antineoplastic agent.

Indications

As a representitive of the compounds of the class of progestins, this drug is used for various forms of cancer, in particular cancer of the breast, kidneys, and others.

Definition

ChEBI: A 3-oxo Delta4-steroid that is pregna-4,6-diene-3,20-dione substituted by a hydroxy group at position 17.

brand name

Megace (Bristol-Myers Squibb); Megace (Par);Citestrol;Co-ervonum;Combiquens;Femagest;Kombiquens;Megecat;Megeron;Megestat;Menoquens;Neo-delpregnin;Niaestine;Niagestine;Novaquin;Novokvens;Novolina;Novoquens;Oracolnal;Ovaban;Ovarid;Pallace;Serial 28;Volidan;Volplan.

World Health Organization (WHO)

Megestrol acetate, a synthetic progestogen, was introduced in the early 1960s as a component in oral contraceptive preparations. In 1967, as a result of new regulations required by the United States Food and Drug Administration, megestrol acetate was submitted to long-term toxicity studies and by the early 1970s it was shown to be associated with an increased incidence of mammary tumours in beagle bitches which led to its withdrawal by several regulatory authorities. Subsequently the validity of the beagle bitch model as a predictor of carcinogenicity of steroid contraceptives has been contested by many national regulatory authorities and megestrol remains available in some countries for contraceptive purposes. In other countries its use is restricted to anticancer treatment. (Reference: (WHODI) WHO Drug Information, 1-3, 5-7, 1984)

Synthesis

Megestrol, 17|á-hydroxy-6|á-methylpregna-4,6-dien-3,20-dione acetate (28.3.9), is a product of dehydrogenation medroxyprogesterone (28.3.7) with chloranil (tetrachloro-p-benzoquinone) in the presence of p-toluenesulfonic acid, which results in the formation of an additional double bond at position C6¨CC7, and subsequent acetylation of the product (28.3.8) leads to the desired megestrol (28.3.9) by acetic anhydride in the presence of p-toluenesulfonic acid.

Megestrol Preparation Products And Raw materials

Raw materials

Preparation Products

17-Hydroxy-6-methylpregn-4-ene-3,20-dione 17-acetate

Less

Megestrol Suppliers

Canada 2 China 132 Europe 2 India 5 South Korea 1 United Kingdom 1 United States 21 Global 164

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Hangzhou Zyter Biological & Chemical Technology Co., Ltd.

Tel: 18858184290; 18858184290
Fax: 0086-571-28313105
Email: sales@zyterpharm.com
Country: China
ProdList: 48
Advantage: 49

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 9387
Advantage: 52

VOT INTERNATIONAL BUSINESS CO.,LTD

Tel: 0536-2456718
Fax: 0536-8231856
Country: China
ProdList: 226
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9648
Advantage: 58

Wuhan Dahua Pharmaceutical Co., Ltd.

Tel: 027-59262863 13277907145 3091977954
Fax: 027-59420980
Country: China
ProdList: 4943
Advantage: 58

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-+86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 11578
Advantage: 59

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
Email: sales@altasci.com.cn
Country: China
ProdList: 4511
Advantage: 55

Wuhan Biocar Bio-Pharm Co., Ltd.

Tel: 86 15387057351
Fax: 86 027 87050469
Email: sales@biocar.cn
Country: China
ProdList: 114
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

Raw material medicin reagent co.,Ltd

Tel
Email: sales@njromanme.com
Country: China
ProdList: 4529
Advantage: 58

WG reagent

Tel: 13391486464
Fax: QQ:14748090
Email: samwjf@163.com
Country: China
ProdList: 3086
Advantage: 55

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29764
Advantage: 68

Shenzhen Simeiquan Biotechnology Co. Ltd

Tel: 18126413629 0755-23311925 2355327053
Fax: 0755-23311925
Email: abel@ycgmp.com
Country: China
ProdList: 5113
Advantage: 58

Shenzhen Sendi Biological Technology Co., Ltd.

Tel: 18124570582 TEL：0755-23574479 2355327139
Fax: 0755-23229476 QQ: 2355327139
Email: siliao02@yccreate.com
Country: China
ProdList: 6116
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 18016230971
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25004
Advantage: 58

PI & PI BIOTECH INC.

Tel: 020-81716320 17788709170
Fax: 020-81716319
Email: Sales@pipitech.com
Country: China
ProdList: 2649
Advantage: 58

Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.

Tel: 027-51831887 15337167856
Fax: 027-51837635 QQ1165326703
Email: hubeixinyuanshun@163.com
Country: China
ProdList: 10295
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-037163312495,13303845143 13303845143
Fax: QQ3001379618
Email: 3001379618@qq.com
Country: China
ProdList: 10378
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57423
Advantage: 58

Finetech Industry Limited

Tel: +86-27-87465837 +8618971612321
Fax: 86 27 87772287
Email: info@finetechnology-ind.com
Country: China
ProdList: 9639
Advantage: 58

Hebei Mojin Biotechnology Co., Ltd

Tel: +86 13288715578 +8613288715578
Email: sales@hbmojin.com
Country: China
ProdList: 12832
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

Wuhan Golt Biotech Co., Ltd.

Tel: +8615389281203
Email: maria@goltbiotech.com
Country: China
ProdList: 970
Advantage: 58

Hebei Qige Biological Technology Co. Ltd

Tel: +86 +8618733132031
Country: CHINA
ProdList: 1303
Advantage: 58

Hebei Chuanghai Biotechnology Co,.LTD

Tel: +86-13131129325
Fax: 86-0311-66562153
Email: sales1@chuanghaibio.com
Country: China
ProdList: 5889
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-029-89586680 +86-18192503167
Fax: +86-29-88380327
Email: 1026@dideu.com
Country: China
ProdList: 7724
Advantage: 58

Longyan Tianhua Biological Technology Co., Ltd

Tel: 0086 18039857276 18039857276
Country: CHINA
ProdList: 2783
Advantage: 58

Hebei Lihe Biotechnology Co.,ltd

Tel: 86-311-80292533 13315122300
Email: sales@lihebiotech.com
Country: CHINA
ProdList: 298
Advantage: 58

Guangzhou Dreampharm Biotechnology Co., Ltd.

Tel: 020-36607679 17825480238
Fax: QQ 3008233717
Email: 3008233746@qq.com
Country: China
ProdList: 9919
Advantage: 12

Hubei Qibu New Material Technology Co., Ltd.

Tel: 0715-8890696 18062324989
Email: 2284979616@qq.com
Country: China
ProdList: 520
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39894
Advantage: 58

Hebei shuoxi biotechnology co. LTD

Tel: +8613081092107
Fax: whatsapp:+8613081092107
Country: CHINA
ProdList: 964
Advantage: 58

Wuhan Xinru Chemical Co., Ltd.

Tel: 15927387915 15337108568
Email: 2769903731@qq.com
Country: China
ProdList: 3336
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-029-81138252 +86-18789408387
Fax: 029-88380327
Email: 1057@dideu.com
Country: China
ProdList: 3884
Advantage: 58

Xi'an Lyna Bio-Tech Co., Ltd.

Tel: 029-84161958 18629577295
Fax: 029-84161958
Email: magic@lynabio.com
Country: China
ProdList: 1062
Advantage: 55

ShangHai Anpel Co, Ltd.

Tel: 18501792038; 18501792038
Email: shanpel@anpel.com.cn
Country: China
ProdList: 9611
Advantage: 58

SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD

Tel: 0755-0755-0755-83725350 13380397412
Fax: 0755-28094224
Email: 3001280422@qq.com
Country: China
ProdList: 10005
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 13675144456
Fax: 025-85563444
Email: sean.lv@synzest.com
Country: China
ProdList: 11438
Advantage: 58

Wuhan Yanzhe Technology Co., Ltd

Tel: 15527250409
Fax: QQ：2692360204
Email: wenhaotian12@163.com
Country: China
ProdList: 4169
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Lingyuan Bebiansen Biological Technology Co., Ltd

Tel: 18642120371
Email: 2837458851@qq.com
Country: China
ProdList: 7995
Advantage: 58

Guangzhou Juntang Technology Co., Ltd

Tel: 020-36607679 13502246435
Email: sales@dmstandards.com
Country: China
ProdList: 10945
Advantage: 58

Shanghai kadel chemical technology co., LTD

Tel: 021-4007787-550 400-7787-550
Email: 2850202386@qq.com
Country: China
ProdList: 10593
Advantage: 58

Less

View Lastest Price from Megestrol manufacturers

Hebei Chuanghai Biotechnology Co,.LTD

Product: Megestrol 3562-63-8
Price: US $10.50/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 ton
Release date: 2024-08-21

Shaanxi Dideu Medichem Co. Ltd

Product: Megestrol 3562-63-8
Price: US $1.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-19

Shaanxi Dideu Medichem Co. Ltd

Product: Megestrol 3562-63-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-26

3562-63-8, MegestrolRelated Search:

CHLOROPHOSPHONAZO III MEGESTROL ACETATE,MEGESTROL 17-ACETATE,MEGESTROL ACETATE-D3,MEGESTROL 17-ACETATE VETRANAL, 100 MG,Megestrol Acetate, Micronized,Megestrol Acetate, Milled Powder Premarin 17-Hydroxy-6-methylpregn-4-ene-3,20-dione 17-acetate Megestrol acetate EP Impurity E (2β)-Methyl Megestrol Acetate 4,7-Dihydro Megestrol Acetate AQMUMBCTNJGBGC-FGPIKTEISA-N Hydroxyprogesterone acetate Medroxyprogesterone Acetate 17-hydroxy-6-methylenepregn-4-ene-3,20-dione 17-acetate Melengestrol acetate Progesterone melengestrol Megestrol Acetate 2-Methyl-1-megestrol Acetate (Megestrol Acetate Impurity) MEGESTROL ACETATE - REFERENCE SPECTRUM Megestrol

17-hydroxy-6-methylpregna-4,6-diene-3,20-dione

20-dione,17-hydroxy-6-methyl-pregna-6-diene-3

4,6-PREGNADIEN-6-METHYL-17-OL-3,20-DIONE

17-ALPHA-HYDROXY-6-METHYL-4,6-PREGNADIENE-3,20-DIONE

MEGESTROL

17-alpha-hydroxy-6-methylpregna-4,6-diene-3,20-dione

Megestrol (base and/or unspecified salts)

C07120

megestrol solution,100ppm

(8R,9S,10R,13S,14S,17R)-17-Acetyl-17-hydroxy-6,10,13-trimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

Megestrol acetate EP Impurity B

Megestrol Acetate Impurity 2(Megestrol Acetate EP Impurity B)(Megestrol)

Megestro

Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-

Megestrol Acetate Impurity 2（Megestrol Acetate EP Impurity B）

Metesterone acetate EP impurity B

Megestrol USP/EP/BP

Megestrol in Methanol

Megestrol 100 μg/ml Acetonitrile

17α-Hydroxy-6-Methyl-4,6-Pregnadiene-3,20-Dione

3562-63-8

Hormone Drugs

Intermediates & Fine Chemicals

Pharmaceuticals

Steroids

3562-63-8